| 1. |
- Hallengren, Bengt, et al.
(författare)
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Normal visual fields as assessed by computerized static threshold perimetry in patients with untreated primary hypothyroidism
- 1989
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Ingår i: Acta Endocrinologica. - 0001-5598. ; 121:4, s. 495-500
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Tidskriftsartikel (refereegranskat)abstract
- In this prospective study, 25 consecutive patients with untreated primary hypothyroidism were tested with a highly sensitive perimetric technique, since a high prevalence of visual field defects has been described in this condition. All patients had clinical hypothyroidism, a serum TSH value greater than 20 mU/l (reference range 0.4-4.0) and decreased/low normal serum total T4 concentration. Visual fields were tested with fully automated threshold-measuring computerized perimetry of the central 30 degrees field. Interpretation of fields included computer-assisted analysis provided by a perimetric statistical programme package. In 23 patients, conventional inspection and computer-assisted analysis showed no visual field defects. Two patients were excluded from the latter analysis: one patient who did not respond adequately at computerized perimetry and in whom manual field tests were entirely normal: one patient who had low sensitivity values in the uppermost parts of both visual fields owing to markedly swollen upper eye lids. In conclusion, although pituitary hyperplasia has been well documented in primary hypothyroidism, the present prospective study clearly indicates that visual field defects are not a common finding in patients with this disease.
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| 2. |
- Thörne, Johan, et al.
(författare)
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Effect of ticlopidine and prostaglandin E on endotoxin-induced pulmonary platelet sequestration in vivo
- 1986
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Ingår i: Circulatory Shock. - 0092-6213. ; 20:1, s. 61-69
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Tidskriftsartikel (refereegranskat)abstract
- Prostaglandin E1 has earlier been shown to decrease pulmonary platelet trapping (PPT) following shock. This experiment was performed to evaluate a new method to study PPT in vivo, and to study the effect of prostaglandin E1 and a new antiplatelet drug (ticlopidine) on PPT in rabbits after i.v. administration of endotoxin. Following platelet labeling with In-111, the rabbits were placed under a scintillation camera for continuous measuring of the activity distribution for 40 minutes. The first five minutes represented reference values, whereafter endotoxin E. coli was injected i.v. The following 2-4 minutes showed a sudden increase of radioactivity over the lungs and a simultaneous decrease over the heart, indicating PPT in the nontreated animals, followed by a slow decrease to almost preshock values during the following 30 minutes. Animals receiving prostaglandin E1 showed a significantly lower activity peak in the lungs after the administration of endotoxin, while the corresponding peak in ticlopidine-treated animals did not differ from that seen in the nontreated animals. In all groups, endotoxin caused a decrease in platelet count, but it was significantly lower in the PGE1-treated animals. The results have shown that this diagnostic model for PPT is reliable and may be used for evaluation of the effect on platelet aggregation in vivo of different drugs
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| 3. |
- Wollmer, Per, et al.
(författare)
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Relation between lung function, exercise capacity, and exposure to asbestos cement
- 1987
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Ingår i: British Journal of Industrial Medicine. - 0007-1072. ; 44:8, s. 542-549
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Tidskriftsartikel (refereegranskat)abstract
- A group of 137 male workers with known exposure (mean 20 fibre years per millilitre) to asbestos cement who had symptoms or signs of pulmonary disease was studied together with a reference group of 49 healthy industrial workers with no exposure to asbestos. Lung function measurements were made at rest and during exercise. Evidence of lung fibrosis was found as well as of obstructive airways disease in the exposed group compared with the reference group. Asbestos cement exposure was related to variables reflecting lung fibrosis but not to variables reflecting airflow obstruction. Smoking was related to variables reflecting obstructive lung disease. Exercise capacity was reduced in the exposed workers and was related to smoking and to lung function variables, reflecting obstructive airways disease. There was no significant correlation between exercise capacity and exposure to asbestos cement.
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| 4. |
- Bauer, M, et al.
(författare)
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Ankle fractures
- 1987
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Ingår i: Foot and Ankle. - 0198-0211. ; 8:1, s. 23-25
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Tidskriftsartikel (refereegranskat)abstract
- The results of three separate studies on ankle fractures are presented. Clinical information is provided concerning the epidemiology and a comparison of closed versus open treatment, and a discussion is presented concerning what results can be expected 30 years after closed treatment for an ankle fracture.
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| 5. |
- Bauer, M, et al.
(författare)
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Supination-eversion fractures of the ankle joint: changes in incidence over 30 years
- 1987
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Ingår i: Foot and Ankle. - 0198-0211. ; 8:1, s. 26-28
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Tidskriftsartikel (refereegranskat)abstract
- The sex- and age-specific incidence has been calculated for ankle fractures from the first part of the 1950s and compared with the 1980s, a 30-year interval. The fractures were also classified according to Lauge-Hansen. Altogether 1784 fractures were found. During that time interval ankle fractures had become more common, particularly those with extensive skeletal involvement, such as the stage IV supination-eversion fractures, which today have an incidence pattern more typical of a fragility fracture in elderly women.
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| 6. |
- Bengner, Urban, et al.
(författare)
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Changes in incidence and prevalence of vertebral fractures during 30 years
- 1988
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Ingår i: Calcified Tissue International. - 1432-0827. ; 42:5, s. 293-296
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Tidskriftsartikel (refereegranskat)abstract
- The age and sex-specific incidence and prevalence of vertebral compression fractures were compared between the 1950s and 1980s in an urban population. In women over 80 years of age the incidence of symptomatic vertebral fractures has increased approximately four times; in elderly men even more. Mainly, low-energy trauma has caused these fractures. Thus, one clinical manifestation of osteoporosis--vertebral fracture--has increased in number, incidence, and prevalence over the last 30 years.
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| 7. |
- Bengnér, Urban, et al.
(författare)
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Epidemiology of ankle fracture 1950 and 1980. Increasing incidence in elderly women
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:1, s. 35-37
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Tidskriftsartikel (refereegranskat)abstract
- During 1980-82, 739 ankle fractures occurred in Malmo. These were compared with 383 ankle fractures occurring in 1950-52. In men there was an increase in the age-specific incidence up to the age of 60, especially in fractures of the lateral malleolus. In women there was an increase in the age-specific incidence above the age of 50, both in lateral malleolar fractures and, even more pronounced, in bi- and tri- malleolar fractures.
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| 8. |
- Bengnér, Urban, et al.
(författare)
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Increasing incidence of tibia condyle and patella fractures
- 1986
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 57:4, s. 334-336
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Tidskriftsartikel (refereegranskat)abstract
- The age and sex specific incidence of tibial condyle fractures and patellar fractures were compared between 1950-55 and 1980-83 in the urban population of Malmo. In elderly women there was an increased incidence over these 30 years for both fracture types.
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| 9. |
- Blomqvist, S, et al.
(författare)
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Early post-traumatic changes in hemodynamics and pulmonary ventilation in alcohol-pretreated pigs
- 1987
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Ingår i: Journal of Trauma. - 0022-5282. ; 27:1, s. 40-44
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Tidskriftsartikel (refereegranskat)abstract
- Time relations among trauma, pulmonary and systemic circulation, and lung function were studied in pigs. Eleven animals (b.w. 25-30 kg) were investigated under balanced anesthesia. Ventilation was mechanically controlled. Hemodynamics, pulmonary ventilation, and gas exchange were serially recorded. Seven animals were pretreated with 40% ethanol in saline and four with saline only. Ninety minutes after the ingestion of alcohol or saline, the animals were subjected to a standardized soft-tissue trauma. Cardiac output decreased significantly 2 minutes after trauma and remained low in both groups throughout the observation period of 30 minutes. Pulmonary vascular resistance was significantly increased in the alcohol-pretreated group but was virtually unchanged in the control animals. Systemic vascular resistance was similarly reduced in the two groups. Total compliance was somewhat lower in alcohol-pretreated animals and 10 minutes after the trauma arterial oxygen tension was significantly lower in the alcohol group than in control animals. Carbon dioxide elimination was reduced after trauma in both groups. It is concluded that pulmonary vascular response increased and that total pulmonary compliance is somewhat decreased shortly after trauma in the alcohol group while gas exchange is almost unchanged. The results indicate a negative interaction between alcohol and trauma
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| 10. |
- Edwards, Birgitta, et al.
(författare)
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Patellar fractures. A 30-year follow-up
- 1989
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Ingår i: Acta Orthopaedica Scandinavica. - : Medical Journals Sweden AB. - 0001-6470. ; 60:6, s. 712-714
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Tidskriftsartikel (refereegranskat)abstract
- Forty patients who had had a patellar fracture during the years 1950-58 were reevaluated 30 years later. A clinical and radiographic examination was performed. Fourteen patients had subjective complaints. Two thirds of the patients who had more than 2-mm diastasis or 1-mm incongruity had complaints and reduced quadriceps strength. Radiographically, all the patients had a reduction in the lateral patellofemoral distance in the axial view with the greatest reduction in the knees with diastasis or incongruity of the fracture.
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