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  • Resultat 331-340 av 1651039
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331.
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333.
  • A Swedish Philhellenic Pamphlet from 1821 : "Will you let that sacred voice that echoes in the tender Swedish heart cry out in vain?”
  • 2022. - 2022
  • Annan publikation (refereegranskat)abstract
    • The first volume of Grifos is a publication of a rare, anonymously published philhellenic pamphlet from the year 1821. It was printed in Stockholm, yet it has hitherto remained uncol­lected by the scholarly community. The pamphlet is published here for the first time with an En­glish translation and a commentary by George Kalpadakis and Vassilios Sabatakakis. In their introduction the authors place the pamphlet in its historical context and discuss its core themes. The original 1821 text, whose images are repro­duced in the final section, has been transcribed and translated by both authors. This rather provocative philhellenic text echoes a few central themes of philhellenism that by the time of its publica­tion had already become part of later frequent­ly repeated rhetoric in philhellenic discourses. Probably in the challenging political climate in Sweden vis-à-vis the Greek war of independence, complex attitudes and ideologies, both for and against the struggle during its early phase, are re­flected in the text.
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334.
  • A, Teschendorff, et al. (författare)
  • The dynamics of DNA methylation covariation patterns in carcinogenesis
  • 2014
  • Ingår i: PLoS Computational Biology. - : Public Library of Science (PLoS). - 1553-734X .- 1553-7358. ; 10:7
  • Tidskriftsartikel (refereegranskat)abstract
    • Recently it has been observed that cancer tissue is characterised by an increased variability in DNA methylation patterns. However, how the correlative patterns in genome-wide DNA methylation change during the carcinogenic progress has not yet been explored. Here we study genome-wide inter-CpG correlations in DNA methylation, in addition to single site variability, during cervical carcinogenesis. We demonstrate how the study of changes in DNA methylation covariation patterns across normal, intra-epithelial neoplasia and invasive cancer allows the identification of CpG sites that indicate the risk of neoplastic transformation in stages prior to neoplasia. Importantly, we show that the covariation in DNA methylation at these risk CpG loci is maximal immediately prior to the onset of cancer, supporting the view that high epigenetic diversity in normal cells increases the risk of cancer. Consistent with this, we observe that invasive cancers exhibit increased covariation in DNA methylation at the risk CpG sites relative to normal tissue, but lower levels relative to pre-cancerous lesions. We further show that the identified risk CpG sites undergo preferential DNA methylation changes in relation to human papilloma virus infection and age. Results are validated in independent data including prospectively collected samples prior to neoplastic transformation. Our data are consistent with a phase transition model of carcinogenesis, in which epigenetic diversity is maximal prior to the onset of cancer. The model and algorithm proposed here may allow, in future, network biomarkers predicting the risk of neoplastic transformation to be identified.
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335.
  • A., Trubetskaya, et al. (författare)
  • The Effect of Wood Composition and Supercritical CO2 Extraction on the Charcoal Production
  • 2019
  • Ingår i: 2019 AIChE Annual Meeting proceedings. - : American Institute of Chemical Engineers.
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • This work demonstrated that the coupling of supercritical carbon dioxide extraction with slow pyrolysis is effective to remove over half of extractives from low quality wood and to generate biochar from remaining solid wood fractions. The high yields of extractives from supercritical carbon dioxide extraction illustrates the potential utilizing of low quality wood as an alternative feedstock for the sustainable production of value-added chemicals. Results showed that supercritical carbon dioxide extraction has neither a strong impact on the physical properties of original wood nor on the yield of solid biochar. These results are promising as they show that the biochar obtained for this renewable feedstock could be used as an alternative to fossil-based coke in applications including ferroalloy industries. Moreover, the heat treatment temperature and supercritical carbon dioxide extraction had a significant impact on the tar yields, leading to the increase in naphthalene, polycyclic aromatic hydrocarbons, aromatic and phenolic fractions with the greater temperature. The differences in gasification reactivity and dielectric properties of solid biochars, composition and yields of liquid products of non-treated pinewood and extracted wood fraction emphasize the impact of supercritical carbon dioxide extraction on the pyrolysis process. 
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340.
  • A U-turn to the Future: Sustainable Urban Mobility since 1850
  • 2020
  • Samlingsverk (redaktörskap) (refereegranskat)abstract
    • From local bike-sharing initiatives to overhauls of transport infrastructure, mobility is one of the most important areas in which modern cities are trying to realize a more sustainable future. Yet even as politicians and planners look ahead, there remain critical insights to be gleaned from the history of urban mobility and the unsustainable practices that still impact our everyday lives. United by their pursuit of a “usable past,” the studies in this interdisciplinary collection consider the ecological, social, and economic aspects of urban mobility, showing how historical inquiry can make both conceptual and practical contributions to the projects of sustainability and urban renewal.
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