| 31. |
- Fainzilber, M
(författare)
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Advantage of knowing nature's secrets
- 1997
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 386:6624, s. 431-431
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 32. |
- Farde, L, et al.
(författare)
-
D2 dopamine receptors and personality traits
- 1997
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 385:6617, s. 590-590
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 33. |
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| 34. |
- Heinzel, T., et al.
(författare)
-
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
- 1997
-
Ingår i: Nature. - : Nature Publishing Group. - 0028-0836 .- 1476-4687. ; 387:6628, s. 43-48
-
Tidskriftsartikel (refereegranskat)abstract
- Transcriptional repression by nuclear receptors has been correlated to binding of the putative co-repressor, N-CoR. A complex has been identified that contains N-CoR, the Mad presumptive co-repressor mSin3, and the histone deacetylase mRPD3, and which is required for both nuclear receptor- and Mad-dependent repression, but not for repression by transcription factors of the ets-domain family. These data predict that the ligand-induced switch of heterodimeric nuclear receptors from repressor to activator functions involves the exchange of complexes containing histone deacetylases with those that have histone acetylase activity.
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| 35. |
- Hieronymus, C.F. 1967-, et al.
(författare)
-
Discrete alternating hotspot islands formed by interaction of magma transport and lithospheric flexure
- 1999
-
Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 397:6720, s. 604-607
-
Tidskriftsartikel (refereegranskat)abstract
- The large-scale geometry and age progression of many hotspot island chains, such as the Hawaiian-Emperor chain, are well explained by the steady movement of tectonic plates over stationary hotspots. But on a smaller scale, hotspot tracks are composed of discrete volcanic islands whose spacing correlates with lithospheric thickness(1). Moreover, the volcanic shields themselves are often not positioned along single lines, but in more complicated patterns, such as the dual line known as the Kea and Loa trends of the Hawaiian islands(2,3). Here we make use of the hypothesis that. island spacing is controlled by lithospheric flexure(1) to develop a simple nonlinear model coupling magma flow, which feeds volcanic growth, to the flexure caused by volcanic loads on the underlying plate. For a steady source of melt underneath a moving lithospheric plate, magma is found to reach the surface and build a chain of separate volcanic edifices with realistic spacing. If a volcano is introduced away from the axis of the chain, as might occur following a change in the direction of plate motion, the model perpetuates the asymmetry for long distances and times, thereby producing an alternating: series of edifices similar to that observed in the Kea and Loa trends of the Hawaiian island chain.
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| 36. |
- Hill, Russell, et al.
(författare)
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Origin of Life
- 1994
-
Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 371, s. 646-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 37. |
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| 38. |
- Hörlein, A. J., et al.
(författare)
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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
- 1995
-
Ingår i: Nature. - : Nature Publishing Group. - 0028-0836 .- 1476-4687. ; 377:6548, s. 397-404
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Tidskriftsartikel (refereegranskat)abstract
- Thyroid-hormone and retinoic-acid receptors exert their regulatory functions by acting as both activators and repressors of gene expression. A nuclear receptor co-repressor (N-CoR) of relative molecular mass 270K has been identified which mediates ligand-independent inhibition of gene transcription by these receptors, suggesting that the molecular mechanisms of repression by thyroid-hormone and retinoic-acid receptors are analogous to the co-repressor-dependent transcriptional inhibitory mechanisms of yeast and Drosophila.
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| 39. |
- Ibanez, CF
(författare)
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Researchers face 'Catch-22' grants trap
- 1999
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 398:6725, s. 280-280
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 40. |
- Josefsson, Agnetha M., et al.
(författare)
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p53 polymorphism and risk of cervical cancer
- 1998
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 396:6711, s. 531-
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Tidskriftsartikel (refereegranskat)
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