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Numrering	Referens	Omslagsbild	Hitta
1191.	Saxne, Tore, et al. (författare) Difference in cartilage proteoglycan level in synovial fluid in early rheumatoid arthritis and reactive arthritis. 1985 Ingår i: The Lancet. - 1474-547X. ; 2/8447:8447, s. 127-128 Tidskriftsartikel (refereegranskat)abstract Cartilage proteoglycans were measured, by the use of an enzyme-linked immunosorbent assay, in synovial fluids obtained from 109 unselected patients attending an outpatient rheumatology clinic because of inflammation of the knee. The content of proteoglycans in synovial fluid was inversely related to the degree of joint destruction shown on X-ray. The proteoglycan concentrations in knee-joint exudates were higher in patients with reactive arthritis than in patients with rheumatoid arthritis having synovitis of corresponding duration and lacking radiological evidence of cartilage destruction. The measurement of proteoglycan levels may therefore be useful in differentiating between the two conditions.
1192.	Schaferhoff, M, et al. (författare) How much donor financing for health is channelled to global versus country-specific aid functions? 2015 Ingår i: Lancet (London, England). - 1474-547X. ; 386:10011, s. 2436-2441 Tidskriftsartikel (refereegranskat)
1193.	Scheltens, Philip, et al. (författare) Alzheimer's disease. 2016 Ingår i: Lancet (London, England). - 1474-547X. ; 388:10043, s. 505-17 Tidskriftsartikel (refereegranskat)abstract Although the prevalence of dementia continues to increase worldwide, incidence in the western world might have decreased as a result of better vascular care and improved brain health. Alzheimer's disease, the most prevalent cause of dementia, is still defined by the combined presence of amyloid and tau, but researchers are gradually moving away from the simple assumption of linear causality as proposed in the original amyloid hypothesis. Age-related, protective, and disease-promoting factors probably interact with the core mechanisms of the disease. Amyloid β42, and tau proteins are established core cerebrospinal biomarkers; novel candidate biomarkers include amyloid β oligomers and synaptic markers. MRI and fluorodeoxyglucose PET are established imaging techniques for diagnosis of Alzheimer's disease. Amyloid PET is gaining traction in the clinical arena, but validity and cost-effectiveness remain to be established. Tau PET might offer new insights and be of great help in differential diagnosis and selection of patients for trials. In the search for understanding the disease mechanism and keys to treatment, research is moving increasingly into the earliest phase of disease. Preclinical Alzheimer's disease is defined as biomarker evidence of Alzheimer's pathological changes in cognitively healthy individuals. Patients with subjective cognitive decline have been identified as a useful population in whom to look for preclinical Alzheimer's disease. Moderately positive results for interventions targeting several lifestyle factors in non-demented elderly patients and moderately positive interim results for lowering amyloid in pre-dementia Alzheimer's disease suggest that, ultimately, there will be a future in which specific anti-Alzheimer's therapy will be combined with lifestyle interventions targeting general brain health to jointly combat the disease. In this Seminar, we discuss the main developments in Alzheimer's research.
1194.	Scheltens, P, et al. (författare) Alzheimer's disease 2021 Ingår i: Lancet (London, England). - 1474-547X. ; 397:10284, s. 1577-1590 Tidskriftsartikel (refereegranskat)
1195.	Scherstén, Tore, 1930, et al. (författare) Hyperthermic liver perfusion chemotherapy in the foregut carcinoid syndrome. 1991 Ingår i: Lancet. - 0140-6736. ; 338:8766, s. 568-9 Tidskriftsartikel (refereegranskat)
1196.	Schieppati, A, et al. (författare) Why rare diseases are an important medical and social issue 2008 Ingår i: Lancet (London, England). - 1474-547X. ; 371:9629, s. 2039-2041 Tidskriftsartikel (refereegranskat)
1197.	Schröder, Fritz H, et al. (författare) Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. 2014 Ingår i: Lancet. - 1474-547X. ; 384:9959, s. 2027-2035 Tidskriftsartikel (refereegranskat)abstract The European Randomised study of Screening for Prostate Cancer (ERSPC) has shown significant reductions in prostate cancer mortality after 9 years and 11 years of follow-up, but screening is controversial because of adverse events such as overdiagnosis. We provide updated results of mortality from prostate cancer with follow-up to 2010, with analyses truncated at 9, 11, and 13 years.
1198.	Schröder, Fritz, et al. (författare) Prostate cancer screening in Europe - Authors' reply. 2015 Ingår i: Lancet (London, England). - 1474-547X. ; 385:9977, s. 1507-8 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
1199.	Semugoma, P, et al. (författare) The irony of homophobia in Africa 2012 Ingår i: Lancet (London, England). - 1474-547X. ; 380:9839, s. 312-314 Tidskriftsartikel (refereegranskat)
1200.	Sewankambo, NK, et al. (författare) Envisioning the futures of global health: three positive disruptions 2023 Ingår i: Lancet (London, England). - 1474-547X. ; 401:10384, s. 1247-1249 Tidskriftsartikel (refereegranskat)

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