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Sökning: L773:0956 7976 OR L773:1467 9280

  • Resultat 51-60 av 65
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51.
  • Rietveld, CA, et al. (författare)
  • Replicability and robustness of genome-wide-association studies for behavioral traits
  • 2014
  • Ingår i: Psychological science. - : SAGE Publications. - 1467-9280 .- 0956-7976. ; 25:11, s. 1975-1986
  • Tidskriftsartikel (refereegranskat)abstract
    • A recent genome-wide-association study of educational attainment identified three single-nucleotide polymorphisms (SNPs) whose associations, despite their small effect sizes (each R2 ≈ 0.02%), reached genome-wide significance ( p < 5 × 10−8) in a large discovery sample and were replicated in an independent sample ( p < .05). The study also reported associations between educational attainment and indices of SNPs called “polygenic scores.” In three studies, we evaluated the robustness of these findings. Study 1 showed that the associations with all three SNPs were replicated in another large ( N = 34,428) independent sample. We also found that the scores remained predictive ( R2 ≈ 2%) in regressions with stringent controls for stratification (Study 2) and in new within-family analyses (Study 3). Our results show that large and therefore well-powered genome-wide-association studies can identify replicable genetic associations with behavioral traits. The small effect sizes of individual SNPs are likely to be a major contributing factor explaining the striking contrast between our results and the disappointing replication record of most candidate-gene studies.
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52.
  • Salvatore, Jessica E., et al. (författare)
  • Disentangling Social-Genetic From Rearing-Environment Effects for Alcohol Use Disorder Using Swedish National Data
  • 2020
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 31:9, s. 1140-1149
  • Tidskriftsartikel (refereegranskat)abstract
    • Investigations of social-genetic effects, whereby a social partner’s genotype affects another’s outcomes, can be confounded by the influence of the social partner’s rearing environment. We used marital information on more than 300,000 couples from Swedish national data to disentangle social-genetic from rearing-environment effects for alcohol use disorder (AUD). Using observational and extended-family designs, we found that (a) marriage to a spouse with a predisposition toward AUD (as indexed by a parental history of AUD) increased risk for developing AUD; (b) this increased risk was not explained by socioeconomic status, the spouse’s AUD status, or contact with the spouse’s parents; and (c) this increased risk reflected the psychological consequences of the spouse having grown up with an AUD-affected parent (i.e., a rearing-environment effect) rather than a social-genetic effect. Findings illustrate that a spouse’s rearing-environment exposures may confer risk for AUD.
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53.
  • Salvatore, Jessica E., et al. (författare)
  • Genetics, the Rearing Environment, and the Intergenerational Transmission of Divorce : A Swedish National Adoption Study
  • 2018
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 29:3, s. 370-378
  • Tidskriftsartikel (refereegranskat)abstract
    • We used classical and extended adoption designs in Swedish registries to disentangle genetic and rearing-environment influences on the intergenerational transmission of divorce. In classical adoption analyses, adoptees (n = 19,715) resembled their biological parents, rather than their adoptive parents, in their history of divorce. In extended adoption analyses, offspring (n = 82,698) resembled their not-lived-with fathers and their lived-with mothers. There was stronger resemblance to lived-with mothers, providing indirect evidence of rearing-environment influences on the intergenerational transmission of divorce. The heritability of divorce assessed across generations was 0.13. We attempted to replicate our findings using within-generation data from adoptive and biological siblings (ns = 8,523–53,097). Adoptees resembled their biological, not adoptive, siblings in their history of divorce. Thus, there was consistent evidence that genetic factors contributed to the intergenerational transmission of divorce but weaker evidence for a rearing-environment effect of divorce. Within-generation data from siblings supported these conclusions.
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54.
  • Sand, Anders, et al. (författare)
  • When Perception Trumps Reality : Perceived, Not Objective, Meaning of Primes Drives Stroop Priming
  • 2017
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 28:3, s. 346-355
  • Tidskriftsartikel (refereegranskat)abstract
    • Is semantic priming driven by the objective or perceived meaning of the priming stimulus? This question is relevant given that many studies suggest that the objective meaning of invisible stimuli can influence cognitive processes and behavior. In an experiment involving 66 participants, we tested how the perceived meaning of misperceived stimuli influenced response times. Stroop priming (i.e., longer response times for incongruent than for congruent prime-target pairs) was observed in trials in which the prime was correctly identified. However, reversed Stroop priming was observed when the prime stimulus was incorrectly identified. Even in trials in which participants reported no perception of the prime and identified the primes at close to chance level (i.e., trials that meet both subjective and objective definitions of being subliminal), Stroop priming corresponded to perceived congruency, not objective congruency. This result suggests that occasional weak percepts and mispercepts are intermixed with no percepts in conditions traditionally claimed to be subliminal, casting doubt on claims of subliminal priming made in previous reports.
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55.
  • Schafmeister, Felix (författare)
  • The Effect of Replications on Citation Patterns: Evidence From a Large-Scale Reproducibility Project
  • 2021
  • Ingår i: Psychological Science. - : SAGE Publications (UK and US). - 1467-9280 .- 0956-7976. ; 32:10, s. 1537-1548
  • Tidskriftsartikel (refereegranskat)abstract
    • Replication of existing research is often referred to as one of the cornerstones of modern science. In this study, I tested whether the publication of independent replication attempts affects the citation patterns of the original studies. Investigating 95 replications conducted in the context of the Reproducibility Project: Psychology, I found little evidence for an adjustment of citation patterns in response to the publication of these independent replication attempts. This finding was robust to the choice of replication criterion, various model specifications, and the composition of the contrast group. I further present some suggestive evidence that shifts in the underlying composition of supporting and disputing citations have likely been small. I conclude with a review of the evidence in favor of the remaining explanations and discuss the potential consequences of these findings for the workings of the scientific process. © The Author(s) 2021.
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56.
  • Schmiedek, Florian, et al. (författare)
  • Keeping It Steady. Older Adults Perform More Consistently on Cognitive Tasks Than Younger Adults
  • 2013
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 24:9, s. 1747-1754
  • Tidskriftsartikel (refereegranskat)abstract
    • People often attribute poor performance to having bad days. Given that cognitive aging leads to lower average levels of performance and more moment-to-moment variability, one might expect that older adults should show greater day-to-day variability and be more likely to experience bad days than younger adults. However, both researchers and ordinary people typically sample only one performance per day for a given activity. Hence, the empirical basis for concluding that cognitive performance does substantially vary from day to day is inadequate. On the basis of data from 101 younger and 103 older adults who completed nine cognitive tasks in 100 daily sessions, we show that the contributions of systematic day-to-day variability to overall observed variability are reliable but small. Thus, the impression of good versus bad days is largely due to performance fluctuations at faster timescales. Despite having lower average levels of performance, older adults showed more consistent levels of performance across days.
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57.
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59.
  • Thunell, E, et al. (författare)
  • Memory for Repeated Images in Rapid-Serial-Visual-Presentation Streams of Thousands of Images
  • 2019
  • Ingår i: Psychological science. - : SAGE Publications. - 1467-9280 .- 0956-7976. ; 30:7, s. 989-1000
  • Tidskriftsartikel (refereegranskat)abstract
    • Human observers readily detect targets in stimuli presented briefly and in rapid succession. Here, we show that even without predefined targets, humans can spot repetitions in streams of thousands of images. We presented sequences of natural images reoccurring a number of times interleaved with either one or two distractors, and we asked participants to detect the repetitions and to identify the repeated images after a delay that could last for minutes. Performance improved with the number of repeated-image presentations up to a ceiling around seven repetitions and was above chance even after only two to three presentations. The task was easiest for slow streams; performance dropped with increasing image-presentation rate but stabilized above 15 Hz and remained well above chance even at 120 Hz. To summarize, we reveal that the human brain has an impressive capacity to detect repetitions in rapid-serial-visual-presentation streams and to remember repeated images over a time course of minutes.
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60.
  • Walter, Kathryn, et al. (författare)
  • Sex Differences in Mate Preferences Across 45 Countries : A Large-Scale Replication
  • 2020
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 31:4, s. 408-423
  • Tidskriftsartikel (refereegranskat)abstract
    • Considerable research has examined human mate preferences across cultures, finding universal sex differences in preferences for attractiveness and resources as well as sources of systematic cultural variation. Two competing perspectives-an evolutionary psychological perspective and a biosocial role perspective-offer alternative explanations for these findings. However, the original data on which each perspective relies are decades old, and the literature is fraught with conflicting methods, analyses, results, and conclusions. Using a new 45-country sample (N = 14,399), we attempted to replicate classic studies and test both the evolutionary and biosocial role perspectives. Support for universal sex differences in preferences remains robust: Men, more than women, prefer attractive, young mates, and women, more than men, prefer older mates with financial prospects. Cross-culturally, both sexes have mates closer to their own ages as gender equality increases. Beyond age of partner, neither pathogen prevalence nor gender equality robustly predicted sex differences or preferences across countries.
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