| 41. |
- Wuestefeld, Anika, et al.
(författare)
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Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories
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Ingår i: Hippocampus. - 1050-9631.
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Tidskriftsartikel (refereegranskat)abstract
- The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer's disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic features. As neuroanatomical schools rely on different cytoarchitectonic definitions of these subregions, it is unclear to what extent their delineations of MTL cortex subregions overlap. Here, we provide an overview of cytoarchitectonic definitions of the entorhinal and parahippocampal cortices as well as Brodmann areas (BA) 35 and 36, as provided by four neuroanatomists from different laboratories, aiming to identify the rationale for overlapping and diverging delineations. Nissl-stained series were acquired from the temporal lobes of three human specimens (two right and one left hemisphere). Slices (50 μm thick) were prepared perpendicular to the long axis of the hippocampus spanning the entire longitudinal extent of the MTL cortex. Four neuroanatomists annotated MTL cortex subregions on digitized slices spaced 5 mm apart (pixel size 0.4 μm at 20× magnification). Parcellations, terminology, and border placement were compared among neuroanatomists. Cytoarchitectonic features of each subregion are described in detail. Qualitative analysis of the annotations showed higher agreement in the definitions of the entorhinal cortex and BA35, while the definitions of BA36 and the parahippocampal cortex exhibited less overlap among neuroanatomists. The degree of overlap of cytoarchitectonic definitions was partially reflected in the neuroanatomists' agreement on the respective delineations. Lower agreement in annotations was observed in transitional zones between structures where seminal cytoarchitectonic features are expressed less saliently. The results highlight that definitions and parcellations of the MTL cortex differ among neuroanatomical schools and thereby increase understanding of why these differences may arise. This work sets a crucial foundation to further advance anatomically-informed neuroimaging research on the human MTL cortex.
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| 42. |
- Shin, D. Y., et al.
(författare)
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Temperature dependence of magnetic anisotropy in ferromagnetic (Ga,Mn)As films : Investigation by the planar Hall effect
- 2007
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Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 76:3
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Tidskriftsartikel (refereegranskat)abstract
- We carried out systematic planar Hall effect (PHE) measurements of GaMnAs ferromagnetic semiconductor film as a function of temperature. The two-step switching of the PHE occurring in the magnetization-reversal process was observed to change significantly as the temperature was increased. To investigate the mechanism responsible for such behavior, the temperature dependence of the PHE was continuously measured (with and without an external magnetic field) after the sample was first magnetized along one of the easy axes to produce an initial single-domain state at 3 K. A detailed temperature dependence of the magnetization direction was then obtained by taking the ratio of the planar Hall resistance measured with and without a magnetic field. As the temperature was increased, the direction of the easy axis of magnetization was observed to change from the [010] crystallographic direction to [110]. This reorientation of the easy axis direction can be understood in terms of the temperature dependence of the relative strengths of the magnetic anisotropy constants (i.e., of the ratio of uniaxial-to-cubic anisotropy) of the GaMnAs film. © 2007 The American Physical Society.
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