| 51. |
- Böthun, Alicia, et al.
(författare)
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Whiplash trauma did not predict jaw pain after 2 years : an explorative study
- 2024
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Ingår i: Clinical Oral Investigations. - : Springer Nature. - 1432-6981 .- 1436-3771. ; 28
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To explore predictive factors for the development and maintenance of jaw pain over a 2-year period.Methods: One hundred nineteen cases (73 women) and 104 controls (59 women), mean age 34.9 years (SD 13.9), attended baseline and 2-year follow-up examinations. The whiplash cases visited the emergency department at Umeå University Hospital, Sweden, with neck pain within 72 h following a car accident, and baseline questionnaires were answered within a month after trauma. Controls were recruited via advertising. Inclusion criteria were age 18–70 years, living in Umeå municipality and Swedish speaking. The exclusion criterion was neck fracture for cases and a previous neck trauma for controls. Validated questionnaires recommended in the standardized Research Diagnostic Criteria for temporomandibular disorders were used. Jaw pain was assessed by two validated screening questions answered with “yes” or “no.” A logistic regression analysis was used to predict the outcome variable jaw pain (yes/no) after 2 years.Results: Whiplash trauma did not increase the odds of development of jaw pain over a 2-year period (OR 1.97, 95% CI 0.53–7.38). However, non-specific physical symptoms (OR 8.56, 95% CI 1.08–67.67) and female gender (OR 4.89, 95% CI 1.09–22.02) did increase the odds for jaw pain after 2 years.Conclusion: The development and maintenance of jaw pain after whiplash trauma are primarily not related to the trauma itself, but more associated with physical symptoms.Clinical relevance: The development of jaw pain in connection with a whiplash trauma needs to be seen in a biopsychosocial perspective, and early assessment is recommended.
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| 52. |
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Challenging life : existential questions as a resource for education
- 2018
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- There is increasing recognition today that young people need to have knowledge about religions and world views in order to live and work in diverse societies. What kind of 'maps' are they provided with through religious, values, and ethics education? Does education address the challenging existential questions that children and adolescents ask about life and the world? This volume addresses different aspects of how existential questions have been dealt with in educational research. It especially draws attention to the Swedish research tradition of focusing on life questions and the interpretation of life in education, but with contemporary international research added. It also addresses ethics education and discusses possible options for the future of existential questions as a resource for education.
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| 53. |
- Claeson, Anna-Sara, 1974-, et al.
(författare)
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Symptoms from masked acrolein exposure suggest altered trigeminal reactivity in chemical intolerance
- 2017
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Ingår i: Neurotoxicology. - : Elsevier. - 0161-813X .- 1872-9711. ; 60, s. 92-98
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Tidskriftsartikel (refereegranskat)abstract
- Background: Chemical intolerance (CI) is a widespread occupational and public health problem characterized by symptoms that reportedly result from low-levels of chemical exposure. The mechanisms behind CI are unknown, however modifications of the chemical senses (rather than toxic processes) have been suggested as key components. The aim of this study was to investigate whether individuals with self-reported CI report more sensory irritation during masked acrolein exposure compared to controls without CI. Methods: Individuals with CI (n = 18) and controls without CI (n = 19) were exposed in an exposure chamber. Each participant took part in two exposure conditions – one with heptane (the masking compound), and one with heptane and acrolein at a dose below previously reported sensory irritation thresholds. The exposures lasted for 60 min. Symptoms and confidence ratings were measured continuously throughout the exposure as were measurements of electrodermal activity and self-reported tear-film break-up time. Participants were blind to exposure condition. Results: Individuals with CI, compared with controls reported greater sensory irritation in the eyes, nose and throat when exposed to acrolein masked with heptane. There was no difference during exposure to heptane. Conclusions: Masked exposure to acrolein at a concentration below the previously reported detection threshold is perceived as more irritating by individuals with CI compared with controls. The results indicate that there is altered trigeminal reactivity in those with CI compared to controls.
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| 54. |
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| 55. |
- Crenshaw, Albert G., et al.
(författare)
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Reliability of near-infrared spectroscopy for measuring forearm and shoulder oxygenation in healthy males and females
- 2012
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Ingår i: European Journal of Applied Physiology. - : Springer. - 1439-6319 .- 1439-6327. ; 112:7, s. 2703-2715
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Tidskriftsartikel (refereegranskat)abstract
- This study determined the day-to-day reliability of NIRS-derived oxygenation responses (a dagger StO(2)%) for isometric contractions and for cuff occlusion. Twenty-four subjects (12 males and 12 females) were tested for 2 days (4-6 days interval). Variables generated were: (1) a dagger StO(2)% for isometric contractions (10, 30, 50 and 70% MVC) for descending trapezius (TD) and extensor carpi radialis (ECR) muscles; (2) slope changes in total haemoglobin (HbTslope) and deoxyhaemoglobin (HHbslope) for the ECR using upper arm venous (VO, 50 mmHg) and arterial occlusion (AO, 250 mmHg); (3) recovery slopes (Rslope) for oxygen saturation (StO(2)) following isometric contractions and AO. For each variable, an intraclass correlation (ICC) was calculated to assess the ability to differentiate between subjects, and limits of agreement (LOA) were computed to assess day-to-day consistency of the measurement. ICCs for Delta StO(2)% were lowest at 10% MVC for both ECR (0.58) and TD (0.55), and highest at 30% MVC for ECR (0.95) and at 70% MVC for TD (0.79). For both muscles, LOA for Delta StO(2)% was lowest at 10% and highest at 50 and 70% MVC. ICC for HbTslope was 0.17. For HHbslope ICC was higher for AO (0.83) than for VO (0.73), and LOA was lower for AO. For the ECR Rslope ICCs ranged from 0.88 to 0.90 for contraction, but was lower for AO (0.33); LOA was lowest at 70% MVC. For trapezius Rslope ICCs ranged from 0.63 to 0.73 and LOA was lowest at 30% MVC. For this study, establishing reliability data for the ECR and TD and including variables commonly reported are expected to have meaning for future NIRS studies of work-related upper-extremity pain as well as for other NIRS research and clinical applications.
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| 56. |
- Daerga, Laila, et al.
(författare)
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Work-related musculoskeletal pain among reindeer herding Sami in Sweden : a pilot study on causes and prevention
- 2004
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Ingår i: International Journal of Circumpolar Health. - 1239-9736 .- 2242-3982. ; 63 Suppl 2, s. 343-348
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Tidskriftsartikel (refereegranskat)abstract
- Objective. To investigate the prevalence and to identify causes of musculoskeletal pain (MSP) among reindeer herding Sami, and to evaluate the impact on the MSP symptoms elicited by an intervention-pre- vention programme (lP programme). Study Design. A prospective cohort study in which alterations in MSP symptoms were documented over a two-year period. Methods. Data were collected from 51 rein- deer herders (26 men, 25 w omen) before and af ter a two-year lP programme. Information on MSP cha- racteristics (affected body regions, pain duration and pain intensity) and exposure to a number of phy- sical and psychosocial risk factors were collected as part of comprehensive health examinations. Cli- nical examinations and interviews complemented self-reported data collected through questionnaires. Results. MSP symptoms were prevalent, both among w omen and men. High exposure to physical risk factors, to a large extent related to extensive use of snowmobiles and motorcycles, was the main cau- se of MSP among men, while psychosocial risk factors were suggested to be more important among wo- men. About one-third of the reindeer herders reported fewer MSP symptoms as a resull of the lP programme. Conclusions. This pilot study suggests that it is possible to reduce the number and the se- verity of the MSP symptoms among reindeer herders by implementing suitably tailored intervention- prevention measures.
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| 57. |
- Dantoft, Thomas Meinertz, et al.
(författare)
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Chemical Intolerance
- 2015
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Ingår i: Current Rheumatology Reviews. - : Bentham Science. - 1573-3971 .- 1875-6360. ; 11:2, s. 167-184
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Tidskriftsartikel (refereegranskat)abstract
- Chemical intolerance (CI) is a term used to describe a condition in which the sufferer experiences a complex array of recurrent unspecific symptoms attributed to low-level chemical exposure that most people regard as unproblematic. Severe CI constitutes the distinguishing feature of multiple chemical sensitivity (MCS). The symptoms reported by CI subjects are manifold, involving symptoms from multiple organs systems. In severe cases of CI, the condition can cause considerable life-style limitations with severe social, occupational and economic consequences. As no diagnostic tools for CI are available, the presence of the condition can only be established in accordance to criteria definitions. Numerous modes of action have been suggested to explain CI, with the most commonly discussed theories involving the immune system, central nervous system, olfactory and respiratory systems as well as altered metabolic capacity, behavioral conditioning and emotional regulation. However, in spite of more than 50 years of research, there is still a great deal of uncertainties regarding the event(s) and underlying mechanism( s) behind symptom elicitation. As a result, patients are often misdiagnosed or offered health care solutions with limited or no effect, and they experience being met with mistrust and doubt by health care professionals, the social care system and by friends and relatives. Evidence-based treatment options are currently unavailable, however, a person-centered care model based on a multidisciplinary treatment approach and individualized care plans have shown promising results. With this in mind, further research studies and health care solutions should be based on a multifactorial and interdisciplinary approach.
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| 58. |
- Dantoft, Thomas M., et al.
(författare)
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Gene expression profiling in persons with multiple chemical sensitivity before and after a controlled n-butanol exposure session
- 2017
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Ingår i: BMJ Open. - : BMJ. - 2044-6055. ; 7:2
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: To investigate the pathophysiological pathways leading to symptoms elicitation in multiple chemical sensitivity (MCS) by comparing gene expression in MCS participants and healthy controls before and after a chemical exposure optimised to cause symptoms among MCS participants.The first hypothesis was that unexposed and symptom-free MCS participants have similar gene expression patterns to controls and a second hypothesis that MCS participants can be separated from controls based on differential gene expression upon a controlled n-butanol exposure.DESIGN: Participants were exposed to 3.7 ppm n-butanol while seated in a windowed exposure chamber for 60 min. A total of 26 genes involved in biochemical pathways found in the literature have been proposed to play a role in the pathogenesis of MCS and other functional somatic syndromes were selected. Expression levels were compared between MCS and controls before, within 15 min after being exposed to and 4 hours after the exposure.SETTINGS: Participants suffering from MCS and healthy controls were recruited through advertisement at public places and in a local newspaper.PARTICIPANTS: 36 participants who considered themselves sensitive were prescreened for eligibility. 18 sensitive persons fulfilling the criteria for MCS were enrolled together with 18 healthy controls.OUTCOME MEASURES: 17 genes showed sufficient transcriptional level for analysis. Group comparisons were conducted for each gene at the 3 times points and for the computed area under the curve (AUC) expression levels.RESULTS: MCS participants and controls displayed similar gene expression levels both at baseline and after the exposure and the computed AUC values were likewise comparable between the 2 groups. The intragroup variation in expression levels among MCS participants was noticeably greater than the controls.CONCLUSIONS: MCS participants and controls have similar gene expression levels at baseline and it was not possible to separate MCS participants from controls based on gene expression measured after the exposure.
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| 59. |
- Daunfeldt, Sven-Olov, et al.
(författare)
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Central bank independence and price stability : evidence from OECD-countries
- 2008
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Ingår i: Oxford Economic Papers. - Oxford : Oxford University Press (OUP). - 0030-7653 .- 1464-3812. ; 60:3, s. 410-422
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we use a non-parametric regression method to compare the transition process from high to low inflation with the implementation dates of central bank independence reforms. In most countries, price stability is achieved before more independence is given to the central bank. Moreover, for those countries which have implemented a central bank independence reform under a high inflation regime, no evidence is found that the reforms have actually led to price stability. This suggests that the credibility of a low inflation goal can be achieved without institutional reforms which grant the central bank more independence from the political policymakers.
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| 60. |
- Dawson, Lorne L., et al.
(författare)
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A comparative analysis of Canadian and Swedish foreign fighters
- 2024
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Ingår i: Behavioral Sciences of Terrorism and Political Aggression. - : Taylor & Francis. - 1943-4472 .- 1943-4480.
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Tidskriftsartikel (refereegranskat)abstract
- While there is a substantial research literature on Western ‘foreign fighters’ – those young men and women from Europe, North America, Australia and elsewhere who traveled to Syria and Iraq, from around 2011–2017, to join jihadist groups engaged in combat – there is a dearth of comparative studies examining the backgrounds of these fighters. National variations in the levels of recruitment have been measured and samples examined to determine the demographics of these fighters, indicating some national variations in who went, how, and maybe why. More fulsome comparative data is needed, however, to detect and measure such differences to gain insight into the factors conditioning the radicalization of these foreign fighters. Calling on original and unique datasets, this study presents the results of a comparative analysis of Canadian and Swedish foreign fighters. In each case the findings are compared with other domestic jihadists as well to delineate if those drawn to fight in Syria and Iraq differ. Clear differences emerge in the basic demographics of these national samples, highlighting some empirical and interpretive issues in need of further analysis.
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