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  • Resultat 70481-70490 av 107836
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70481.
  • Nilsson, Göran, et al. (författare)
  • Loss of pulp vitality correlated with the duration of the interim restoration and the experience of the dentist : A retrospective study
  • 2023
  • Ingår i: The Journal of prosthetic dentistry (Print). - : Elsevier. - 0022-3913 .- 1097-6841. ; 130:6, s. 833-839
  • Tidskriftsartikel (refereegranskat)abstract
    • STATEMENT OF PROBLEM: The second most common biological complication in fixed prosthodontics is loss of pulp vitality, which may lead to restoration loss. While reasons for loss of pulp vitality are unclear, 2 potential contributing factors, duration of the interim restoration and operator experience, have not been fully investigated.PURPOSE: The purpose of this retrospective study was to investigate whether the duration of the interim restoration or the experience of the dentist was correlated with loss of pulp vitality.MATERIAL AND METHODS: Fixed prosthetic restorations placed between 2005 and 2012 were retrospectively analyzed. Abutment teeth supporting single-unti or multiunit restorations were evaluated regarding loss of pulp vitality. The Mann-Whitney U test and simple logistic regression were used, with α=.05 for the subsequent multiple logistic regression. The experience of dental professionals was defined by the number of treatments performed and coupled with failure rate by using an analysis of variance.RESULTS: One hundred seventy-four dentists made 15 879 restorations, of which 1136 failed during the observation period, a failure rate of 7.2%. Two hundred fifty restorations were randomly selected from the failed restorations, and a corresponding 250 restorations were randomly selected from nonfailed restorations for the control group. Increased duration with interim replacement was linked to a higher risk of loss of pulp vitality (P<.001). Failure rate in the dentist group varied from 0% to 100%. No significant differences in failure rate were found among dentists who did few restorations and those who performed larger numbers of restorations.CONCLUSIONS: The results of the present study suggest that operator experience does not affect failure rate. However, extended time with an interim restoration was a contributing factor to the loss of pulp vitality.
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70482.
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70483.
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70484.
  • Nilsson, Gert, 1947- (författare)
  • On the measurement of evaporative water loss : methods and clinical applications
  • 1977
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The new method for measurement of water loss by evaporation from the skin described in paper I, offers a high degree of accuracy and improved sensitivity in comparison with devices reported previously. Rapid recordings can be made by technically untrained persons both in clinical departments and in the laboratory.Using this method, the average insensible perspiration from the skin of healthy adult subjects at rest was found to be 381, 526 and 695 gr per day at ambient temperatures of 22°, 27° and 30°C, respectively. On the head, hands and feet the evaporation rate was high, while on other body surface areas more moderate values were recorded,In a clinical study on newborn infants, a linear relationship between the evaporative water loss from the skin and the ambient humidity was found. At an ambient temperature of 34.5°c and an ambient relative humidity of 50% the average transepidermal water loss was calculated to be 8.1 g/m2h.In burned patients high evaporation rates from about 140 g/m2h to over 220 g/m2h were recorded on the injured skin surfaces. Biological dressings were only slightly permeable to water vapour, while the permeability of the artificial dressings tested was generally high.By recording the rate of increase in vapour concentration in a closed measurement chamber placed over the exposed abdominal cavity during surgery, the water loss by evaporation from wounds and exteriorized viscera was determined. At incisions of minor extent the evaporative water loss was low, while at larger incisions with exteriorized viscera the water loss by evaporation from the wound exceeded the basal cutaneous perspiration of healthy adult subjects.
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70485.
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70486.
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70487.
  • Nilsson, Gunnel, et al. (författare)
  • Quantitative Analysis of Zopiclone, N-desmethylzopiclone, Zopiclone N-oxide and 2-Amino-5-chloropyridine in Urine Using LC-MS-MS
  • 2014
  • Ingår i: Journal of Analytical Toxicology. - : Oxford University Press (OUP): Policy F. - 0146-4760 .- 1945-2403. ; 38:6, s. 327-334
  • Tidskriftsartikel (refereegranskat)abstract
    • A simple LC-MS/MS method was validated to allow determination of zopiclone (ZOP), Ndesmethylzopiclone (NDZOP), zopiclone N-oxide (ZOPNO) and 2-amino-5 chloropyridine (ACP) in urine at concentrations up to 3000 ng/mL within 3.5 min. This method was used for quantitative analysis of the analytes in authentic urine samples obtained 10 h after oral administration of zopiclone (Imovane®) and in aliquots of the same urine samples after different storage conditions. Additionally, pH of each studied urine sample was measured over time. The results showed that formation of ACP occurred at elevated pH and/or temperature by degradation of ZOP, NDZOP and ZOPNO. This method was also applied to samples obtained from two female victims of drug-facilitated assault. One sample had been exposed to long-term storage conditions at different temperatures and at pH>8.2, which resulted in high concentrations of ACP. The other sample, which was exposed to pH <6.5, showed no formation of ACP. ACP is formed both from ZOP and from its metabolites NDZOP and ZOPNO depending on the pH of the urine, time of storage and/or the temperature conditions. For correct interpretation in forensic cases ZOP, its major metabolites and ACP should be analyzed. When ACP is identified in urine the concentrations of ZOP, NDZOP and ZOPNO should be interpreted with great caution.
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70488.
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70489.
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70490.
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