| 61. |
- Höijer, Karin, et al.
(författare)
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"Vi har fått syn på hur viktig den praktiska kunskapen är” : Lärarutbildare på fyra lärosäten om att utbilda under pandemin
- 2021
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Ingår i: ABSTRACTS LÄRARLÄRDOM 2021.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Mat och matlagning beskrivs ofta som själva kärnan i skolämnet hem- och konsumentkunskap (HK). Att utbilda nya lärare inom ämnet med för således att praktisk matlagning ingår som en central del. I och med Coronapandemin ändrades förutsättningarna för att bedriva undervisning, vilket påverkade förutsättningarna för undervisning i praktisk matlagning vid de fyra lärosätena som bedriver utbildning av HK-lärare. Vad innebär det för lärarutbildare att bedriva undervisning i praktiska moment under en pandemi? I det här projektet samlades lärarutbildare från Göteborg universitet, Högskolan Kristianstad, Umeå universitet samt Uppsala universitet i fokusgrupper i två omgångar för att berätta vad pandemin inneburit för undervisningen i praktisk matlagning, vilka lösningar som har framkommit och vilka lärdomar man tar med sig in i framtiden. En första intervjuomgång genomfördes i oktober 2020 och uppföljningsintervjuer gjordes under april och maj 2021. Preliminära resultat visade att den praktiska matlagningen inte bara handlade om matlagningsmetoder utan allt det som händer “runt omkring”. De förändrade förutsättningarna påverkade inte nödvändigtvis studenternas förutsättningar att uppnå lärandemålen men det uttrycktes en oro för att den tysta kunskap som ofta genereras i det nära fysiska mötet mellan människor gått förlorad. Denna studie är den första i sitt slag som inkluderar lärare inom högre utbildning för ämnet HK från samtliga utbildningsorter och de preliminära resultaten väcker nya frågeställningar kring lärandemålens formuleringar och deras relevans för framtidens HK-lärare.
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| 62. |
- Hörnaeus, Katarina, et al.
(författare)
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Mass spectrometry data from a quantitative analysis of protein expression in gills of immuno-challenged blue mussels (Mytilus edulis)
- 2016
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Ingår i: Data in Brief. - Elsevier : Elsevier BV. - 2352-3409. ; 8, s. 470-473
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Tidskriftsartikel (refereegranskat)abstract
- Here, we provide the dataset associated with our research article on the potential effects of ocean acidification on antimicrobial peptide (AMP) activity in the gills of Mytilus edulis, "Impact of ocean acidification on antimicrobial activity in gills of the blue mussel (Mytilus edulis)" [1]. Blue mussels were stimulated with lipopolysaccharides and samples were collected at different time points post injection. Protein extracts were prepared from the gills, digested using trypsin and a full in-depth proteome investigation was performed using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). Protein identification and quantification was performed using the MaxQuant 1.5.1.2 software, "MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification" [2].
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| 63. |
- Isehed, Catrine, et al.
(författare)
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Effectiveness of enamel matrix derivative on the clinical and microbiological outcomes following surgical regenerative treatment of peri-implantitis : A randomized controlled trial
- 2016
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Ingår i: Journal of Clinical Periodontology. - Hoboken, USA : Wiley-Blackwell Publishing Inc.. - 0303-6979 .- 1600-051X. ; 43:10, s. 863-873
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Tidskriftsartikel (refereegranskat)abstract
- Objective: This randomized clinical trial aimed at comparing radiological, clinical and microbial effects of surgical treatment of peri-implantitis alone or in combination with enamel matrix derivative (EMD).Methods: Twenty-six subjects were treated with open flap debridement and decontamination of the implant surfaces with gauze and saline preceding adjunctive EMD or no EMD. Bone level (BL) change was primary outcome and secondary outcomes were changes in pocket depth (PD), plaque, pus, bleeding and the microbiota of the peri-implant biofilm analyzed by the Human Oral Microbe Identification Microarray over a time period of 12 months.Results: In multivariate modelling, increased marginal BL at implant site was significantly associated with EMD, the number of osseous walls in the peri-implant bone defect and a Gram+/aerobic microbial flora, whereas reduced BL was associated with a Gram-/anaerobic microbial flora and presence of bleeding and pus, with a cross-validated predictive capacity (Q(2) ) of 36.4%. Similar, but statistically non-significant, trends were seen for BL, PD, plaque, pus and bleeding in univariate analysis.Conclusion: Adjunctive EMD to surgical treatment of peri-implantitis was associated with prevalence of Gram+/aerobic bacteria during the follow-up period and increased marginal BL 12 months after treatment.
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| 64. |
- Jansson-Fröjmark, Markus, et al.
(författare)
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Stimulus control for insomnia : A systematic review and meta-analysis
- 2024
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Ingår i: Journal of Sleep Research. - : John Wiley & Sons. - 0962-1105 .- 1365-2869. ; 33:1
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Tidskriftsartikel (refereegranskat)abstract
- Stimulus control (SC) is commonly viewed as an evidence-based treatment for insomnia, but it has not been evaluated comprehensively with modern review and meta-analytic techniques. The aim of the current study was thus to perform a systematic review and meta-analysis of trials that examine the efficacy of stimulus control for insomnia. A systematic search for eligible articles and dissertations was conducted in six online bibliographic databases. The 11 included studies, with the majority published between 1978 and 1998, were randomised controlled and experimental studies in adults, comparing stimulus control for insomnia with passive and active comparators and assessing insomnia symptoms as outcomes. A random effects model was used to determine the standardised mean difference Hedge's g at post-treatment and follow-up for three sleep diary measures: the number of awakenings, sleep onset latency, and total sleep time. A test for heterogeneity was conducted, forest plots were produced, the risk of publication bias was estimated, and the study quality was assessed. In the trials identified, stimulus control resulted in small to large improvements on sleep onset latency and total sleep time, relative to passive comparators (g = 0.38-0.85). Compared with active comparators, the improvements following stimulus control were negligible (g = 0.06-0.30). Although methodological uncertainties were observed in the included trials, stimulus control appears to be an efficacious treatment for insomnia when compared with passive comparators and with similar effects to active comparators. More robust studies are, however, warranted before stronger conclusions are possible to infer.
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| 65. |
- Jensen, Gordon L., et al.
(författare)
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Guidance for assessment of the inflammation etiologic criterion for the GLIM diagnosis of malnutrition : A modified Delphi approach
- 2024
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Ingår i: JPEN - Journal of Parenteral and Enteral Nutrition. - : John Wiley & Sons. - 0148-6071 .- 1941-2444. ; 48:2, s. 145-154
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundThe Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) criteria, with diagnosis confirmed by fulfillment of any combination of at least one phenotypic and at least one etiologic criterion. The original GLIM description provided limited guidance regarding assessment of inflammation, and this has been a factor impeding further implementation of the GLIM criteria. We now seek to provide practical guidance for assessment of inflammation.MethodsA GLIM-constituted working group with 36 participants developed consensus-based guidance through a modified Delphi review. A multiround review and revision process served to develop seven guidance statements.ResultsThe final round of review was highly favorable, with 99% overall “agree” or “strongly agree” responses. The presence of acute or chronic disease, infection, or injury that is usually associated with inflammatory activity may be used to fulfill the GLIM disease burden/inflammation criterion, without the need for laboratory confirmation. However, we recommend that recognition of underlying medical conditions commonly associated with inflammation be supported by C-reactive protein (CRP) measurements when the contribution of inflammatory components is uncertain. Interpretation of CRP requires that consideration be given to the method, reference values, and units (milligrams per deciliter or milligram per liter) for the clinical laboratory that is being used.ConclusionConfirmation of inflammation should be guided by clinical judgment based on underlying diagnosis or condition, clinical signs, or CRP.
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| 66. |
- Jourdain, Elsa, et al.
(författare)
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Influenza Virus in a Natural Host, the Mallard : Experimental Infection Data
- 2010
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 5:1
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Tidskriftsartikel (refereegranskat)abstract
- Wild waterfowl, particularly dabbling ducks such as mallards (Anas platyrhynchos), are considered the main reservoir of low-pathogenic avian influenza viruses (LPAIVs). They carry viruses that may evolve and become highly pathogenic for poultry or zoonotic. Understanding the ecology of LPAIVs in these natural hosts is therefore essential. We assessed the clinical response, viral shedding and antibody production of juvenile mallards after intra-esophageal inoculation of two LPAIV subtypes previously isolated from wild congeners. Six ducks, equipped with data loggers that continually monitored body temperature, heart rate and activity, were successively inoculated with an H7N7 LPAI isolate (day 0), the same H7N7 isolate again (day 21) and an H5N2 LPAI isolate (day 35). After the first H7N7 inoculation, the ducks remained alert with no modification of heart rate or activity. However, body temperature transiently increased in four individuals, suggesting that LPAIV strains may have minor clinical effects on their natural hosts. The excretion patterns observed after both reinoculations differed strongly from those observed after the primary H7N7 inoculation, suggesting that not only homosubtypic but also heterosubtypic immunity exist. Our study suggests that LPAI infection has minor clinically measurable effects on mallards and that mallard ducks are able to mount immunological responses protective against heterologous infections. Because the transmission dynamics of LPAIVs in wild populations is greatly influenced by individual susceptibility and herd immunity, these findings are of high importance. Our study also shows the relevance of using telemetry to monitor disease in animals.
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| 67. |
- Järhult, Josef D., et al.
(författare)
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Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards
- 2011
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Ingår i: PLOS ONE. - San Francisco, CA : Public Library of Science (PLoS). - 1932-6203. ; 6:9
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Tidskriftsartikel (refereegranskat)abstract
- Oseltamivir (Tamiflu®) is the most widely used drug against influenza infections and is extensively stockpiled worldwide as part of pandemic preparedness plans. However, resistance is a growing problem and in 2008-2009, seasonal human influenza A/H1N1 virus strains in most parts of the world carried the mutation H274Y in the neuraminidase gene which causes resistance to the drug. The active metabolite of oseltamivir, oseltamivir carboxylate (OC), is poorly degraded in sewage treatment plants and surface water and has been detected in aquatic environments where the natural influenza reservoir, dabbling ducks, can be exposed to the substance. To assess if resistance can develop under these circumstances, we infected mallards with influenza A/H1N1 virus and exposed the birds to 80 ng/L, 1 µg/L and 80 µg/L of OC through their sole water source. By sequencing the neuraminidase gene from fecal samples, we found that H274Y occurred at 1 µg/L of OC and rapidly dominated the viral population at 80 µg/L. IC₅₀ for OC was increased from 2-4 nM in wild-type viruses to 400-700 nM in H274Y mutants as measured by a neuraminidase inhibition assay. This is consistent with the decrease in sensitivity to OC that has been noted among human clinical isolates carrying H274Y. Environmental OC levels have been measured to 58-293 ng/L during seasonal outbreaks and are expected to reach µg/L-levels during pandemics. Thus, resistance could be induced in influenza viruses circulating among wild ducks. As influenza viruses can cross species barriers, oseltamivir resistance could spread to human-adapted strains with pandemic potential disabling oseltamivir, a cornerstone in pandemic preparedness planning. We propose surveillance in wild birds as a measure to understand the resistance situation in nature and to monitor it over time. Strategies to lower environmental levels of OC include improved sewage treatment and, more importantly, a prudent use of antivirals.
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| 68. |
- Jönsson, K. Ingemar, et al.
(författare)
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Sexual patterns of prebreeding energy reserves in the common frog Rana temporaria along a latitudinal gradient
- 2009
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Ingår i: Ecography. - : Wiley. - 0906-7590 .- 1600-0587. ; 32:5, s. 831-839
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Tidskriftsartikel (refereegranskat)abstract
- The ability to store energy is an important life history trait for organisms facing long periods without energy income, and in particular for capital breeders such as temperate zone amphibians, which rely on stored energy during reproduction. However, large scale comparative studies of energy stores in populations with different environmental constraints on energy allocation are scarce. We investigated energy storage patterns in spring (after hibernation and before reproduction) in eight common frog Rana temporaria populations exposed to different environmental conditions along a 1600 km latitudinal gradient across Scandinavia (range of annual activity period is 3-7 months). Analyses of lean body weight (eviscerated body mass), weight of fat bodies, liver weight, and liver fat content, showed that 1) post-hibernation/pre-breeding energy stores increased with increasing latitude in both sexes, 2) males generally had larger energy reserves than females and 3) the difference in energy stores between sexes decreased towards the north. Larger energy reserves towards the north can serve as a buffer against less predictable and/or less benign weather conditions during the short activity period, and may also represent a risk-averse tactic connected with a more pronounced iteroparous life history. In females, the continuous and overlapping vitellogenic activity in the north may also demand more reserves in early spring. The general sexual difference could be a consequence of the fact that, at the time of our sampling, females had already invested their energy into reproduction in the given year (i.e. their eggs were already ovulated), while the males' main reproductive activities (e.g. calling, mate searching, sexual competition) occurred later in the season.
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| 69. |
- Karabag, Solmaz Filiz, 1972-, et al.
(författare)
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The Global, Regional, National, Sectoral, Economic, and Commercial Impact of the Russo-Ukrainian War and the Emerging Second Cold War
- 2022
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Ingår i: Journal of Applied Economics and Business Research. - Canada : JOURNAL APPLIED ECONOMICS & BUSINESS RESEARCH. - 1927-033X. ; 12:2, s. 58-70
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- This paper suggests that the ongoing Russo-Ukrainian war and existing rivalries among future global leaders, such as the USA vs. China, NATO vs. Russia, and China vs. India, may result in a second Cold War. A new global order and the emerging second Cold War will have many impacts on global, regional, national, and political economies and sectors, as well as commercial and business activities. This paper elaborates on the new(de)globalization, diminishing national and regional economic powers, and environmental challenges. Nations will develop new industrial policies and try to secure global supply chains and material flow. At the same time, itis expected that investment in defense, energy, and food sectors will increase to shore up national and regional security. Tourism and other travel-based sectors, such as sports events, might degrow. These wars might deinternationalize the activities of corporations who would need to develop new business processes, organizational forms, and technological capabilities to protect their existing markets and businesses. Based on these arguments and discussions, the paper calls for studies to examine new research ideas and suggest empirical research to expand our understanding and support the informed decision-making of policymakers and managers.
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| 70. |
- Källström, Lisa, et al.
(författare)
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The role of place in city centre retailing
- 2021
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Ingår i: Place Branding and Public Diplomacy. - : Springer Science and Business Media LLC. - 1751-8040 .- 1751-8059. ; 17:1, s. 36-49
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Tidskriftsartikel (refereegranskat)abstract
- City centre offerings, including shopping, restaurants and cafés, and a lively atmosphere are vital place attributes, which together with several other elements create an attractive place. However, city centre retailing is facing serious competition from e-commerce and external shopping malls, and dying city centres appear to have become a worldwide epidemic in the last decade. To retain visitors in the city centre is a prioritized issue and a current topic, for both retail and place branding research. In the present study the role of different elements of city centre retailing in the promotion of a city as a retail destination is explored by analysing photos published on Instagram by a Town Centre Management initiative. The following research question is answered: What role can the place play in city centre retailing? The study is inter-disciplinary, showing how retail attributes and place elements can reinforce each other and together offer opportunities for unique customer experience in a city centre, for the benefit of both retailing and the city brand. Three dominant visual themes of the place’s role in the marketing of a city centre are identified: the place as a frame, the place as a living room, and the place as a stage.
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