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Sökning: WFRF:(Ahlin Cecilia)

  • Resultat 31-34 av 34
  • Föregående 123[4]
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31.
  • Wegman [Palmebäck-Wegman], Pia, et al. (författare)
  • Genetic alterations in the K-ras gene influence the prognosis in patients with cervical cancer treated by radiotherapy
  • 2011
  • Ingår i: International Journal of Gynecological Cancer. - Lippincott Williams & Wilkins. - 1048-891X. ; 21:1, s. 86-91
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: A high incidence of K-Ras mutations has been identified in a variety of human cancers, especially in codon 12, 13, and 61. Nevertheless, the presence of K-Ras mutations in cervical cancer remains controversial. The aim of this study was to investigate possible mutations in exon 1 and 2 of the K-Ras gene and to assess whether K-Ras mutation status had prognostic and predictive significance and were linked to clinicopathological parameters. Methods: Genomic DNA from 107 patients with cervical cancer, treated with radio-chemotherapy, were examined for mutations in the coding exons 1 and 2, including exon/intron borders of the K-Ras gene using single-stranded conformation polymorphism and sequence analyses. Results: K-Ras mutations were detected in 11 patients (10%). Seven tumors showed a mutation in codon 59, 3 tumors in codon 38, and 1 tumor in codon 13. In 6 of the cases with a mutation in codon 59, an additional alteration located in codon 65 was found. Patients with K-Ras mutations had significantly worse recurrence-free survival (P = 0.03), and an association between K-Ras status and distant metastases was also seen (P = 0.04). Conclusions: The present data indicate that K-Ras mutations are relatively uncommon in cervical cancer but associates with poorer prognosis, especially in the subset of squamous cell carcinomas. There is a need for new markers in cervical cancer to improve individual treatment, but whether K-Ras mutation status is a potential biomarker in this situation needs further investigations in larger tumor series and in more regions of the K-Ras gene.
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32.
  • Österman, Cecilia, et al. (författare)
  • Conceptual and Practical Strategy Work to Promote Ergonomics/Human Factors in Sweden
  • 2018
  • Ingår i: 20th Congress of the International Ergonomics Association, IEA 2018,Florence, Italy,2018-08-26 - 2018-08-30. - Springer.
  • Konferensbidrag (refereegranskat)abstract
    • This paper describes the results of the conceptual and practical strategy work performed by the Swedish Ergonomics and Human Factors Society (EHSS) today. The rationale of EHSS is to strengthen the quality of ergonomics/human factors knowledge and practice in Sweden and form a multidisciplinary platform across disciplines and professions for collaboration and for knowledge sharing. EHSS gathers about 350 members, representing different occupations in industry, academia and the public sector. Together, EHSS members hold knowledge and experience in physical, cognitive and organizational ergonomics and its application in working life and society. The overall aim of this paper is to inspire related societies and stakeholders to initiate discussions about strategies and future projects that allow for collaboration and knowledge sharing. Proposedly follow the EHSS model where we have formed a multidisciplinary platform for collaboration across disciplines and professions. The activities initiated and supported by EHSS are one step towards broadening the knowledge and application of HFE in Sweden, and to comprise new arenas of specialization. By participating in the key areas in society such as teaching, standardization, product development and occupational safety and health, the work of EHSS is one piece of the puzzle to improve human activities in the future. The vision is that together, we can improve safety, efficiency and well-being for all.
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33.
  • Österman, Cecilia, 1971-, et al. (författare)
  • Conceptual and Practical Strategy Work to Promote Ergonomics/Human Factors in Sweden
  • 2019
  • Ingår i: Proceedings of the 20th Congress of the International Ergonomics Association (IEA 2018). - Cham : Springer. - 978-3-319-96079-1 - 978-3-319-96080-7 ; s. 320-329
  • Konferensbidrag (refereegranskat)abstract
    • This paper describes the results of the conceptual and practical strategy work performed by the Swedish Ergonomics and Human Factors Society (EHSS) today. The rationale of EHSS is to strengthen the quality of ergonomics/human factors knowledge and practice in Sweden and form a multidisciplinary platform across disciplines and professions for collaboration and for knowledge sharing. EHSS gathers about 350 members, representing different occupations in industry, academia and the public sector. Together,EHSS members hold knowledge and experience in physical, cognitive andorganizational ergonomics and its application in working life and society. The overall aim of this paper is to inspire related societies and stakeholders to initiate discussions about strategies and future projects that allow for collaborationa nd knowledge sharing. Proposedly follow the EHSS model where we have formed a multidisciplinary platform for collaboration across disciplinesand professions. The activities initiated and supported by EHSS are one steptowards broadening the knowledge and application of HFE in Sweden, and to comprise new arenas of specialization. By participating in the key areas in society such as teaching, standardization, product development and occupationalsafety and health, the work of EHSS is one piece of the puzzle to improvehuman activities in the future. The vision is that together, we can improve safety, efficiency and well-being for all.
  •  
34.
  • Österman, Cecilia, 1971-, et al. (författare)
  • Conceptual and Practical Strategy Work to Promote Ergonomics/Human Factors in Sweden
  • 2019
  • Ingår i: Advances in Intelligent Systems and Computing. - 2194-5357. - 978-3-319-96079-1 ; 821, s. 320-329
  • Konferensbidrag (refereegranskat)abstract
    • This paper describes the results of the conceptual and practical strategy work performed by the Swedish Ergonomics and Human Factors Society (EHSS) today. The rationale of EHSS is to strengthen the quality of ergonomics/human factors knowledge and practice in Sweden and form a multidisciplinary platform across disciplines and professions for collaboration and for knowledge sharing. EHSS gathers about 350 members, representing different occupations in industry, academia and the public sector. Together, EHSS members hold knowledge and experience in physical, cognitive and organizational ergonomics and its application in working life and society. The overall aim of this paper is to inspire related societies and stakeholders to initiate discussions about strategies and future projects that allow for collaboration and knowledge sharing. Proposedly follow the EHSS model where we have formed a multidisciplinary platform for collaboration across disciplines and professions. The activities initiated and supported by EHSS are one step towards broadening the knowledge and application of HFE in Sweden, and to comprise new arenas of specialization. By participating in the key areas in society such as teaching, standardization, product development and occupational safety and health, the work of EHSS is one piece of the puzzle to improve human activities in the future. The vision is that together, we can improve safety, efficiency and well-being for all.
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  • Föregående 123[4]
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