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  • Johansson, Emma, et al. (författare)
  • Prompt Proton Decay in the Vicinity of 56Ni
  • 2007
  • Ingår i: International Conference on Proton Emitting Nuclei and Related Topics,Lisbon, Portugal,2007-06-17 - 2007-06-23. - American Institute of Physics.
  • Konferensbidrag (refereegranskat)abstract
    • A new decay mode, the so called prompt proton decay, was discovered in 1998. It has since proven to be an important decay mechanism for several neutron deficient nuclei in the A similar to 60 region. To measure with high accuracy the energies and angular distributions of these protons, a state-of-the-art charged particle detector - LuWuSiA - was developed. It was first utilized during a fusion-evaporation reaction experiment performed at Argonne National Laboratory, U.S.A. In this contribution, the characteristics of the prompt proton decay are discussed along with the special features of LuWuSiA as well as a revisit to the prompt proton decay in Cu-58.
  • Podolyak, Z, et al. (författare)
  • High Angular Momentum States Populated in Fragmentation Reactions
  • 2006
  • Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - Elsevier. - 0370-2693. ; 632:2-3, s. 203-206
  • Tidskriftsartikel (refereegranskat)abstract
    • The population of metastable states produced in relativistic-energy fragmentation of a U-238 beam has been measured. For states with angular momentum greater than or similar to 20h, a much higher population than expected has been observed. By introducing a collective component to the generation of angular momentum the experimental data can be understood. This is the first time that a collective degree of freedom has be shown to play a major role in such high-energy collisions. (c) 2005 Elsevier B.V. All rights reserved.
  • Sparding, Timea, et al. (författare)
  • Cognitive Functioning in Clinically Stable Patients with Bipolar Disorder I and II
  • 2015
  • Ingår i: Plos One. - 1932-6203. ; 10:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives Bipolar disorder is accompanied by cognitive impairments, which persists during euthymic phases. The purpose of the present study was to identify those neuropsychological tests that most reliably tell euthymic bipolar patients and controls apart, and to clarify the extent to which these cognitive impairments are clinically significant as judged from neuropsychological norms. Patients with bipolar disorder (type I: n = 64; type II: n = 44) and controls (n = 86) were examined with a comprehensive neuropsychological test battery yielding 47 measures of executive functioning, speed, memory, and verbal skills. Multivariate analysis was used to build a model of cognitive performance with the ability to expose underlying trends in data and to reveal cognitive differences between patients and controls. Patients with bipolar disorder and controls were partially separated by one predictive component of cognitive performance. Additionally, the relative relevance of each cognitive measure for such separation was decided. Cognitive tests measuring set shifting, inhibition, fluency, and searching (e.g., Trail Making Test, Color-Word) had strongest discriminating ability and most reliably detected cognitive impairments in the patient group. Both bipolar disorder type I and type II were associated with cognitive impairment that for a sizeable minority is significant in a clinical neuropsychological sense. We demonstrate a combination of neuropsychological tests that reliably detect cognitive impairment in bipolar disorder.
  • Sørensen, J. B., et al. (författare)
  • Evolution of overall survival (OS) in patients (pts) with incident NSCLC in Denmark and Sweden : A SCAN-LEAF study analysis from the I-O Optimise initiative
  • 2019
  • Ingår i: Annals of Oncology. - Oxford University Press. - 0923-7534. ; 30:Suppl 2, s. 16-17
  • Konferensbidrag (refereegranskat)abstract
    • Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care, and outcomes for pts with NSCLC in Scandinavia. Here, we report temporal OS trends among pts diagnosed with incident NSCLC from 2005 to 2015 in Denmark and Sweden. Methods: The SCAN-LEAF Danish and Swedish cohorts were established by linking respective national registries and include all adult pts diagnosed with incident NSCLC from Jan 2005 to Dec 2015 (follow-up to Dec 2016). The Kaplan–Meier method was used to estimate OS at 1, 3, and 5 yrs by histology (non-squamous cell [NSQ] or squamous cell [SQ]), TNM stage, and yr of diagnosis; changes in OS over time were assessed using the Cochrane–Armitage test. Results: 31,939 pts in Denmark and 30,067 pts in Sweden were diagnosed with NSCLC from 2005 to 2015. Most were diagnosed at stage IV (51.6% and 48.4%, respectively) and had NSQ histology (54.4% and 60.4%). Statistically significant trends (P < 0.05) for improved OS accompanied by an absolute OS rate increase of > 5% over the analysis period were seen for NSQ pts at 1 yr for all stages in both countries (Table); at 3 yrs for stages I–IIIB in Denmark (P ≤ 0.027), and stages I–II (P ≤ 0.0013) in Sweden; and at 5 yrs for stages I–II (P ≤ 0.026) in both countries. For SQ pts, this was seen only at 1 yr for stage IIIA in Denmark and stage I in Sweden (Table), and at 5 yrs for stage IIIA in Denmark (p = 0.02). Conclusions: Despite some improvements between 2005 and 2015, mainly in the short-term survival of pts with early-stage NSCLC, long-term OS rates for pts with late-stage disease did not change significantly and remained low. Even in pts with early-stage disease, OS outcomes were suboptimal, with a particular unmet need in the SQ population. Future analyses including data after 2015 will evaluate the potential impact on OS of increased use of new TKIs and immune checkpoint inhibitors.
  • Unger, M. M., et al. (författare)
  • Unimpaired postprandial pancreatic polypeptide secretion in Parkinson's disease and REM sleep behavior disorder
  • 2013
  • Ingår i: Movement Disorders. - 0885-3185. ; 28:4, s. 529-533
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Pancreatic polypeptide is released immediately after food ingestion. The release is operated by vagal-abdominal projections and has therefore been suggested as a test for vagal nerve integrity. Pathoanatomical and clinical studies indicate vagal dysfunction in early Parkinson's disease (PD). Methods: We assessed the postprandial secretion of pancreatic polypeptide and motilin in healthy controls (n = 18) and patients with idiopathic rapid-eye-movement sleep behavior disorder (iRBD, n = 10), a potential premotor stage of PD, as well as in drug-naive (n = 19) and treated (n = 19) PD patients. Results: The postprandial pancreatic polypeptide secretion showed a physiological pattern in all groups and even an enhanced response in drug-naive PD and iRBD. Motilin concentrations correlated with pancreatic polypeptide concentrations. Conclusions: Postprandial pancreatic polypeptide secretion is not a suitable test for vagal nerve integrity in PD. The unimpaired pancreatic polypeptide response in iRBD and PD might be explained by partially intact vagal-abdominal projections or compensatory mechanisms substituting a defective neuronal brain–gut axis.
  • Ölvander, J., et al. (författare)
  • Preface
  • 2018
  • Ingår i: Proceedings of NordDesign : Design in the Era of Digitalization, NordDesign 2018. - Linköping : Design Research Society. - 9789176851852
  • Konferensbidrag (populärvet., debatt m.m.)
  • Ölvander, J., et al. (författare)
  • Preface
  • 2018
  • Ingår i: 13th Biennial Norddesign Conference, NordDesign 2018. - The Design Society.
  • Tidskriftsartikel (refereegranskat)
  • Acosta Navarro, J. C., et al. (författare)
  • Amplification of Arctic warming by past air pollution reductions in Europe
  • 2016
  • Ingår i: Nature Geoscience. - 1752-0894. ; 9:4, s. 277-
  • Tidskriftsartikel (refereegranskat)abstract
    • The Arctic region is warming considerably faster than the rest of the globe(1), with important consequences for the ecosystems(2) and human exploration of the region(3). However, the reasons behind this Arctic amplification are not entirely clear(4). As a result of measures to enhance air quality, anthropogenic emissions of particulate matter and its precursors have drastically decreased in parts of the Northern Hemisphere over the past three decades(5). Here we present simulations with an Earth system model with comprehensive aerosol physics and chemistry that show that the sulfate aerosol reductions in Europe since 1980 can potentially explain a significant fraction of Arctic warming over that period. Specifically, the Arctic region receives an additional 0.3Wm(-2) of energy, and warms by 0.5 degrees C on annual average in simulations with declining European sulfur emissions in line with historical observations, compared with a model simulation with fixed European emissions at 1980 levels. Arctic warming is amplified mainly in fall and winter, but the warming is initiated in summer by an increase in incoming solar radiation as well as an enhanced poleward oceanic and atmospheric heat transport. The simulated summertime energy surplus reduces sea-ice cover, which leads to a transfer of heat from the Arctic Ocean to the atmosphere. We conclude that air quality regulations in the Northern Hemisphere, the ocean and atmospheric circulation, and Arctic climate are inherently linked.
  • Andersson, Lise-Lotte, et al. (författare)
  • Gamma-ray Spectroscopy of Excited States in 61Zn
  • 2006
  • Ingår i: European Physical Journal A. Hadrons and Nuclei. - Springer. - 1434-6001. ; 30:2, s. 381-390
  • Tidskriftsartikel (refereegranskat)abstract
    • The Zn-61(30)31 isotope has been produced at the Oak Ridge National Laboratory in the fusion-evaporation reaction Ca-40(Mg-24, 2pn)Zn-61 at 104 MeV. The experimental set-up allowed gamma-rays to be detected in the CLARION Ge detector array in coincidence with the detection of recoiling nuclei in the focal plane at the end of the recoil mass spectrometer. This provides a unique identification of gamma-rays belonging to Zn-61. The excited states have been explored by means of recoil-gamma gamma coincidences, and the resulting decay scheme comprises almost 70 transitions. The data reveal numerous non-yrast states and suggest a revised spin and parity assignment for a previously observed superdeformed band. The resulting decay scheme is compared to predictions from different sets of large-scale shell model calculations.
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