- Conde, Lucia, et al.
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
Ingår i: Nature Genetics. - 1061-4036 .- 1546-1718. ; 42:8, s. 661-664
- <p>To identify susceptibility loci for non-Hodgkin lymphoma subtypes, we conducted a three-stage genome-wide association study. We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 x 10(-29) and rs7755224, combined P = 2.00 x 10(-19); r(2) = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility. We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 x 10(-9)).</p>