SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Olsson Rolf) "

Sökning: WFRF:(Olsson Rolf)

Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
31.
  • Bratt, O, et al. (författare)
  • Sons of men with prostate cancer : their attitudes regarding possible inheritance of prostate cancer, screening, and genetic testing
  • 1997
  • Ingår i: Urology. - Elsevier. - 0090-4295. ; 50:3, s. 5-360
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVES: To study attitudes regarding possible inheritance of prostate cancer among sons of men with prostate cancer.METHODS: A questionnaire was sent to 69 men with prostate cancer and their 101 unaffected sons. All participants were also interviewed by telephone. Sociodemographic data were collected, as were data about the fathers' disease.RESULTS: The response rate was high; 100 sons (99%) and 65 fathers (94%) answered all questions. Sixty of the sons claimed they had worries about having an increased risk of prostate cancer due to possible inheritance. About 90% of the sons wanted to know whether prostate cancer was inheritable (66 definitely and 24 probably), were positively inclined to undergo screening (65 definitely and 27 probably), and to undergo genetic testing (50 definitely and 41 probably), provided there had been multiple cases of prostate cancer in their family. An interest to know whether prostate cancer could be inherited was more frequent among sons with less than 12 years of education, worries about inheritance, younger age, a father treated with curative intent, and with children of their own, especially if sons. Interest in genetic testing was associated with less than 12 years of education and with worries about inheritance.CONCLUSIONS: A large majority of healthy men with a family history of prostate cancer were interested in knowing whether the disease could be inherited and were positively inclined to undergo screening and genetic testing. Our findings indicate that genetic counseling and a screening program could have beneficial psychological effects in families with multiple cases of prostate cancer.
  •  
32.
  • Broomé, Ulrika, et al. (författare)
  • Natural history and outcome in 32 Swedish patients with small duct primary sclerosing cholangitis (PSC)
  • 2002
  • Ingår i: Journal of Hepatology. - Elsevier. - 0168-8278. ; 36:5, s. 586-589
  • Tidskriftsartikel (refereegranskat)abstract
    • Background/Aims: This study aims at describing the natural history and outcome of small duct primary sclerosing cholangitis (PSC). Methods: Thirty-two patients with small duct PSC were studied. The average time taken for diagnosis was 69 (1-168) months. The median follow-up time was 63 (1-194) months. Results: All patients including one who underwent liver transplantation because of end-stage liver disease and hepatocellular carcinoma were alive at follow-up. None developed cholangiocarcinoma. In 27 patients repeated cholangiographic examinations were done after a median time of 72 (12-192) months from first ERCP. Four developed features of large duct PSC. Conclusions: Small duct PSC rarely progresses to large bile duct PSC and it seems to have a benign course in most patients and no development of cholangiocarcinoma was found. (C) 2002 European Association for the Study of the Liver. Published by Elsevier Science B.V. All rights reserved.
  •  
33.
  • Bucin, Dragan, et al. (författare)
  • Heart transplantation across the antibodies against HLA and ABO
  • 2006
  • Ingår i: Transplant International. - Springer. - 1432-2277. ; 19:3, s. 239-244
  • Tidskriftsartikel (refereegranskat)abstract
    • We have intentionally performed heart transplantation in a 5-year-old child, despite the most unfavourable risk factors for patient survival; the presence of high level of antibodies against donor's human leucocyte antigen (HLA) class I/II and blood group antigens. Pretransplant treatment by mycophenolate mofetil, prednisolone, tacrolimus, intravenous immunoglobulin, rituximab, protein-A immunoadsorption (IA) and plasma exchange reduced antibody titres against the donor's lymphocytes from 128 to 16 and against the donor's blood group antigen from 256 to 0. The patient was urgently transplanted with a heart from an ABO incompatible donor (A(1) to O). A standard triple-drug immunosuppressive protocol was used. No hyperacute rejection was seen. Antibodies against the donor's HLA antigens remained at a low level despite three acute rejections. Rising anti-A(1) blood group antibodies preceded the second rejection and were reduced by two blood group-specific IAs and remained at a low level. The patient is doing well despite the persistence of donor-reactive antibodies.
  •  
34.
  • Bülow, Margareta, et al. (författare)
  • Do dysphagic patients with an absent pharyngeal swallow have a shorter survival than dysphagic patients with pharyngeal swallow? Prognostic importance of a therapeutic videoradiographic swallowing study (TVSS).
  • 2005
  • Ingår i: Acta Radiologica. - John Wiley and Sons Inc.. - 1600-0455. ; 46:2, s. 126-131
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose:To study survival in two groups of dysphagic patients - one group unable to elicit the pharyngeal stage of swallow (APS) and another group with pharyngeal swallow (WPS) - and to compare recommendations regarding nutrition and therapeutic strategies based on the therapeutic swallowing study. Material and Methods: In this retrospective study, the records of dysphagic patients who have undergone a therapeutic videoradiographic swallowing study (TVSS) were reviewed. Forty patients without pharyngeal swallow were matched for age and gender with 40 patients with pharyngeal swallow; altogether 80 patients were included in the study. Survival was registered at 3, 12, and 72 months after the TVSS. Results: In this study, the APS group had a significantly shorter survival time (P = 0.0030) compared to the WPS group when followed-up at 12 months. In the APS group, most patients (37.5% (15/40)) died within the 3 months after TVSS. At 72 months, 62.5% (25/40) of the patients in the APS group had died. In the WPS group, 5% (2/40) had died within 3 months and 47.4% (19/40) after 12 months. At 72 months, 52.5% (21/40) of the patients in the WPS group had died. Regarding nutritional and therapeutic recommendations based on TVSS, 34/40 in the APS group were recommended no oral intake. Eighteen naso-gastric tubes were placed directly after TVSS. The therapeutic strategies recommended were head-positioning, thermal tactile stimulation, and tongue exercises (in 8 patients). In the WPS group, all patients were recommended oral intake. Diet modification was recommended in 29 patients. The therapeutic strategies recommended were head-positioning, thermal tactile stimulation, tongue exercises, supraglottic swallow, and effortful swallow (in 24 patients). Conclusion: Patients unable to elicit the pharyngeal stage of swallow had a shorter survival time than patients with pharyngeal swallow, probably due to a more severe underlying disease. Tube feeding was more frequent in the APS group. Fewer therapeutic strategies were recommended compared to the WPS group. In the WPS group, diet modification was frequent. Several patients had different therapeutic strategies. At the end of the study, 8/40 patients (20%) in the APS group had recovered and regained the ability to elicit the pharyngeal stage of swallow. All eight had achieved active swallowing rehabilitation.
  •  
35.
  • Bülow, Margareta, et al. (författare)
  • Supraglottic swallow, effortful swallow, and chin tuck did not alter hypopharyngeal intrabolus pressure in patients with pharyngeal dysfunction.
  • 2002
  • Ingår i: Dysphagia. - Springer. - 1432-0460. ; 17:3, s. 197-201
  • Tidskriftsartikel (refereegranskat)abstract
    • Simultaneous videoradiography and solid-state manometry (videomanometry) were performed in 8 patients (4 women, 4 men; age range = 46-81 years, mean age = 70 years) with pharyngeal dysfunction in order to disclose any changes in intrabolus pressure during swallowing maneuvers. Five of the patients had severe pharyngeal dysfunction with frequent misdirected swallows. Three of the patients had moderate pharyngeal dysfunction with delayed initiation of pharyngeal swallow. Three different swallowing techniques were applied: supraglottic swallow, effortful swallow, and chin tuck. Pharyngeal intrabolus pressure was analyzed at the level of the inferior pharyngeal constrictor. Supraglottic swallow, effortful swallow, and chin tuck did not alter peak amplitude or duration of the intrabolus pressure.
  •  
36.
  • Bülow, Margareta, et al. (författare)
  • Videomanometric analysis of supraglottic swallow, effortful swallow, and chin tuck in healthy volunteers
  • 1999
  • Ingår i: Dysphagia. - Springer. - 1432-0460. ; 14:2, s. 67-72
  • Tidskriftsartikel (refereegranskat)abstract
    • Simultaneous videoradiography and solid-state manometry (videomanometry) was applied in eight healthy volunteers (four women, four men; age range 25-64 years, mean age 41 years) without swallowing problems. Three different swallowing techniques were tested; supraglottic swallow, effortful swallow, and chin tuck. Seven videoradiographic variables and six manometric variables were analyzed. The supraglottic swallowing technique did not differ significantly from that of the control swallows. The effortful swallow had a significantly (p = 0.0001) reduced hyoid-mandibular distance preswallow due to an elevation of the hyoid and the larynx, which caused a significantly (p = 0.007) reduced maximal hyoid movement and a significantly (p = 0.009) reduced laryngeal elevation during swallow. The chin tuck swallow had a significantly (p = 0. 001) reduced laryngohyoid distance and also a significantly (p = 0. 004) reduced hyoid-mandibular distance. The chin tuck swallow also displayed significantly (p = 0.003) weaker pharyngeal contractions. Videomanometry allows for analysis of bolus transport, movement of anatomical structures, and measurement of intraluminal pressures. These variables are important when evaluating swallowing techniques. In the present study, we made a few observations that never have been reported before. When healthy volunteers performed supraglottic swallow, they performed the technique somewhat differently. Therefore, we assume dysphagic patients would need a substantial period of training to perform a technique efficiently. Chin tuck could impair protection of the airways in dysphagic patients with weak pharyngeal constrictor muscles.
  •  
37.
  • Bülow, Margareta, et al. (författare)
  • Videomanometric analysis of supraglottic swallow, effortful swallow, and chin tuck in patients with pharyngeal dysfunction
  • 2001
  • Ingår i: Dysphagia. - Springer. - 1432-0460. ; 16:3, s. 190-195
  • Tidskriftsartikel (refereegranskat)abstract
    • Simultaneous videoradiography and solid-state manometry (videomanometry) was performed in 8 patients (4 women, 4 men; age range = 46-81 years, mean age = 70 years) with pharyngeal dysfunction. Five patients had severe pharyngeal dysfunction with frequent misdirected swallows. Three patients had moderate pharyngeal dysfunction with delayed initiation of pharyngeal swallow. Three different swallowing techniques were used: supraglottic swallow, effortful swallow, and chin tuck. Ten video radiographic variables and six manometric variables were analyzed. Contrast media penetration to the airways was analyzed regarding number of events and level of penetration. Supraglottic swallow, effortful swallow, and chin tuck did not reduce the number of misdirected swallows, but effortful swallow and chin tuck significantly (p = 0.008) reduced the depth of contrast penetration into the larynx and trachea. There was no significant improvement of pharyngeal retention. Chin tuck reduced the distance between the thyroid and the hyoid and the distance between the mandible and the hyoid. No other measured variable was significantly altered. This study shows that none of the different swallowing techniques reduced the number of misdirected swallows. However, there was a significantly reduced depth of the misdirected swallows. The swallowing techniques did not seem to prevent the occurrence of retention or improve weak pharyngeal constrictor muscles in this group of patients with severe to moderate dysfunction.
  •  
38.
  • Bülow, Margareta, et al. (författare)
  • Videoradiographic analysis of how carbonated thin liquids and thickened liquids affect the physiology of swallowing in subjects with aspiration on thin liquids.
  • 2003
  • Ingår i: Acta Radiologica. - John Wiley and Sons Inc.. - 1600-0455. ; 44:4, s. 366-372
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To analyze how carbonated thin liquids affected the physiology of swallowing in dysphagic patients. Material and Methods: 40 patients were analyzed; 36 were neurologically impaired. During a therapeutic videoradiographic swallowing examination the patients had to swallow liquids with the following consistencies three times: thin, thickened and carbonated. The liquids were given in doses of 3 x 5 ml. The swallows were analyzed regarding penetration/aspiration, pharyngeal transit time and pharyngeal retention. Results: Significant difference was found regarding penetration/aspiration when comparisons were made between thin liquid and carbonated thin liquid (p<0.0001). Carbonated liquid reduced the penetration to the airways. The comparison between thin liquid and thickened liquid (p<0.0001) showed significant less penetration with thickened liquids. Pharyngeal transit time was reduced both when comparing thin liquid with thin carbonated liquid (p<0.0001) and thickened liquid (p<0.0001). Pharyngeal retention was significantly reduced (p<0.0001) with carbonated thin liquid compared to thickened liquid. The comparison of thin liquids and carbonated thin liquids showed p = 0.0013, thin and thickened liquids p = 0.0097. Conclusions: Carbonated liquids reduced penetration/aspiration into the airways, reduced pharyngeal retention and pharyngeal transit time became shorter. Therefore, carbonated liquids are a valuable treatment option for patients with penetration/aspiration. Thickened liquids may still be an option for patients who cannot tolerate carbonated liquids and liquids with this consistency are safer than thin liquids.
39.
  • Carlson, Jonas, et al. (författare)
  • Can orthogonal lead indicators of propensity to atrial fibrillation be accurately assessed from the 12-lead ECG?
  • 2005
  • Ingår i: Europace. - Oxford University Press. - 1532-2092. ; 7:Suppl 2, s. 39-48
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: When analyzing P-wave morphology, the vectorcardiogram(VCG) has been shown useful to identify indicators of propensity to atrial fibrillation (AF). Since VCG is rarely used in the clinical routine, we wanted to investigate if these indicators could be accurately determined in VCG derived from standard 12-lead ECG (dVCG).Methods: ECG and VCG recordings from 21 healthy subjects and 20 patients with a history of AF were studied. dVCG was calculated from ECG using the inverse Dower transform. Following signal averaging of P-waves, comparisons were madebetween VCG and dVCG, where three parameters characterizing signal shape and 15 parameters describing the P-wave morphology were used to assess the compatibility of the two recording techniques. The latter parameters were alsoused to compare the healthy and the AF groups.Results: After transformation, P-wave shape was convincingly preserved. P-wave morphology parameters were consistent within the respective groups when comparing VCG and dVCG, with better preservation observed in the healthy group.Conclusion VCG derived from routine 12-lead ECG may be a useful alternate method for studying orthogonal P-wave morphology.
40.
  • Carlson, Jonas, et al. (författare)
  • Classification of Electrocardiographic P-wave Morphology
  • 2000
  • Ingår i: Proceedings of the 39th IEEE Conference on Decision and Control, 2000.. - IEEE - Institute of Electrical and Electronics Engineers Inc.. - 0-7803-6638-7 ; 2, s. 1804-1809
  • Konferensbidrag (övrigt vetenskapligt)abstract
    • The atrial activity of the human heart is normally visible in the ECG as a P-wave. In patients with intermittent atrial fibrilation, a different P-wave morphology can sometimes be seen, indicating atrial conduction defects. The purpose of this study was to develop a method to discriminate between such P-waves and normal ones. 20 recordings of each type were used in a classification which, based on impulse response analysis of the P-wave and linear discrimination between various parameters, produced a correct classification in 37 of the 40 recordings (sensitivity 95%, specificity 90%)
Skapa referenser, mejla, bekava och länka
Åtkomst
fritt online (39)
Typ av publikation
tidskriftsartikel (107)
konferensbidrag (35)
rapport (9)
annan publikation (4)
bokkapitel (3)
bok (2)
visa fler...
proceedings (redaktörskap) (1)
doktorsavhandling (1)
forskningsöversikt (1)
licentiatavhandling (1)
visa färre...
Typ av innehåll
refereegranskat (139)
övrigt vetenskapligt (34)
populärvet., debatt m.m. (1)
Författare/redaktör
Olsson, Rolf, (62)
Johansson, Rolf, (40)
Ekberg, Olle, (35)
Robertsson, Anders, (11)
Olsson, Bertil, (11)
Lindgren, Stefan (11)
visa fler...
Olsson, Tomas (10)
Sandberg-Gertzen, Ha ... (10)
Almer, Sven (9)
Hultcrantz, Rolf (8)
Lööf, Lars, (8)
Nilsson, Håkan, (8)
Larsson, Rolf, (7)
Bergquist, Annika (7)
Holm, M. (6)
Ohlsson, Bodil, (6)
Danielsson, Åke (6)
Nilsson, Klas, (6)
Bülow, Margareta, (6)
Ekbom, Anders (5)
Björnsson, Einar (5)
Wallerstedt, Sven (5)
Adolfsson, Rolf, (4)
Olsson, Lennart, (4)
Ericsson, Rolf, (4)
Loof, L (4)
Thorsson, Ola, (4)
Alfredsson, Joakim, (4)
Danielsson, Ake, (4)
Berg, Sören, (4)
Thorlacius, Henrik, (3)
Simren, Magnus (3)
Simrén, Magnus, 1966 ... (3)
Nyberg, Lars, (3)
Holm, Magnus, (3)
Olsson, Håkan, (3)
Bolmsjö, Gunnar (3)
Landin-Olsson, Mona, (3)
Olsson, A (3)
Stål, Per, (3)
Johansson, Bengt, (3)
Olsson, Sigvard (3)
Loof, Lars, (3)
Askling, Johan, (3)
Sundkvist, Göran, (3)
Olsson, Magnus, (3)
Ståhl, Fredrik, (3)
Bengtsson, Johan (3)
Tunestål, Per, (3)
Haage, Mathias, (3)
visa färre...
Lärosäte
Lunds universitet (111)
Uppsala universitet (25)
Linköpings universitet (21)
Karolinska Institutet (21)
Göteborgs universitet (14)
Umeå universitet (10)
visa fler...
Luleå tekniska universitet (5)
Kungliga Tekniska Högskolan (4)
Mälardalens högskola (4)
Örebro universitet (4)
Högskolan i Jönköping (2)
Mittuniversitetet (2)
Chalmers tekniska högskola (2)
Blekinge Tekniska Högskola (2)
Sveriges Lantbruksuniversitet (2)
Högskolan Kristianstad (1)
Stockholms universitet (1)
RISE (1)
Riksantikvarieämbetet (1)
visa färre...
Språk
Engelska (151)
Svenska (7)
Tyska (1)
Kinesiska (1)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (106)
Teknik (40)
Naturvetenskap (19)
Lantbruksvetenskap (3)
Samhällsvetenskap (3)
Humaniora (1)

År

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy