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Sökning: WFRF:(Af Klinteberg Britt)

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41.
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42.
  • Freidenfelt, Jenny, et al. (författare)
  • Exploring adult personality and psychopathy tendencies in former childhood hyperactive delinquent males
  • 2007
  • Ingår i: Journal of Individual Differences. - : Hogrefe Publishing Group. - 1614-0001 .- 2151-2299. ; 28:1, s. 27-36
  • Tidskriftsartikel (refereegranskat)abstract
    • The focus of this article is on (1) the possible influence of childhood hyperactive behavior on adult psychopathy, and (2) how adult, clinically rated, psychopathy tendencies are related to self-reported personality. The sample comprised 152 male subjects, including young lawbreakers (n = 98) and controls (n = 54), prospectively studied over their lifetime. Ratings of childhood behavior were obtained from a psychiatrist and data on adult personality (using the Karolinska Scales of Personality and a shortened form of the Eysenck Personality Questionnaire) and psychopathy were obtained using the Psychopathy Check List (PCL). Subjects with high PCL as adults (n = 36) scored higher than low PCL subjects (n = 116) on the majority of the personality dimensions studied, even when controlling for criminality. Former childhood hyperactive subjects (n = 26) displayed higher impulsivity and hostility than nonhyperactive subjects (n = 126) when criminality was controlled for. Among the high PCL group subjects there was an overrepresentation of childhood hyperactive males. They displayed significantly higher impulsivity and verbal aggression than their respective nonhyperactive counterparts and were characterized by extreme scores on several psychopathy-related personality scales. Further, there was a significant interaction effect between hyperactivity and PCL on the narrow/noninclusive form of impulsivity. The findings of the present personality-based approach were in favor of childhood hyperactivity being crucial as a risk indicator in the development of psychopathic tendencies.
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43.
  • Freidenfelt Liljeberg, Jenny, et al. (författare)
  • Poor school bonding and delinquency over time : Bidirectional effects and sex differences
  • 2011
  • Ingår i: Journal of Adolescence. - : Wiley. - 0140-1971 .- 1095-9254. ; 34:1, s. 1-9
  • Tidskriftsartikel (refereegranskat)abstract
    • The association between poor school bonding and delinquency has only been partly addressed in earlier research. Using a longitudinal design, the objective of our study was to investigate possible bidirectional effects and sex differences between adolescents’ experienced school bonding and self-rated delinquency over time. A total of 788 adolescents (353 boys and 435 girls) were investigated by questionnaire at age 14 and 16. Poor school attachment and commitment as well as poor teacher attachment were found to be stronger determinants of delinquency for males than for females. Delinquency predicted poor school commitment for both boys and girls, and poor school attachment for girls, thus indicating bidirectional effects over time and sex differences in some of the bidirectional effects. The study concludes that the delinquency propensity of adolescent boys may be affected by all school bonding dimensions, whereas for girls it is their relationship with their teachers that is of significance.
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44.
  • Grigorenko, Elena L., et al. (författare)
  • Aggressive behaviour, related conduct problems, and variation in genes affecting dopamine turnover
  • 2010
  • Ingår i: Aggressive Behavior. - : Wiley. - 0096-140X .- 1098-2337. ; 36:3, s. 158-176
  • Tidskriftsartikel (refereegranskat)abstract
    • A number of dopamine-related genes have been implicated in the etiology of violent behavior and conduct problems. Of these genes, the ones that code for the enzymes that influence the turnover of dopamine (DA) have received the most attention. In this study, we investigated 12 genetic polymorphisms in four genes involved with DA functioning (COMT, MAOA and MAOB, and DβH) in 179 incarcerated male Russian adolescents and two groups of matched controls: boys without criminal records referred to by their teachers as (a) “troubled-behavior-free” boys, n=182; and (b) “troubled-behavior” boys, n=60. The participants were classified as (1) being incarcerated or not, (2) having the DSM-IV diagnosis of conduct disorder (CD) or not, and (3) having committed violent or nonviolent crimes (for the incarcerated individuals only). The findings indicate that, although no single genetic variant in any of the four genes differentiated individuals in the investigated groups, various linear combinations (i.e., haplotypes) and nonlinear combinations (i.e., interactions between variants within and across genes) of genetic variants resulted in informative and robust classifications for two of the three groupings. These combinations of genetic variants differentiated individuals in incarceration vs. nonincarcerated and CD vs. no-CD groups; no informative combinations were established consistently for the grouping by crime within the incarcerated individuals. This study underscores the importance of considering multiple rather than single markers within candidate genes and their additive and interactive combinations, both with themselves and with nongenetic indicators, while attempting to understand the genetic background of such complex behaviors as serious conduct problems.
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45.
  • Grigorenko, Elena L., et al. (författare)
  • Exploring interactive effects on genes and environments in etiology of individual differences in reading comprehension
  • 2007
  • Ingår i: Development and Psychopathology. - 0954-5794 .- 1469-2198. ; 19:4, s. 1089-1103
  • Tidskriftsartikel (refereegranskat)abstract
    • It is established that reading and reading-related processes are heritable; genes thus play an important role in the foundation of individual differences in reading. In this article, we focus on one facet of reading–comprehension. Comprehension is a higher order cognitive skill that requires many other cognitive processes for it to unfold completely and successfully. One such process is executive functioning, which has been associated with genetic variation in the catechol-O-methyltransferase (COMT) gene. Genotypes and haplotypes of four single nucleotide polymorphisms in COMT were investigated in 179 incarcerated adolescent delinquents. Four hierarchical logistic regression models predicting the presence/absence of comprehension difficulties were fitted to the data; genetic variation in COMT and the presence/absence of maternal rejection were investigated as main effects and as effects acting interactively. Three out of four interaction terms were found to be important predictors of individual differences in comprehension. These findings were supported by the results of the haplotype analyses, in which the four investigated polymorphisms were considered simultaneously.
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46.
  • Grigorenko, Elena L., et al. (författare)
  • Personality, intelligence, and somatic and mental health disturbances in a time of societal change : A study of Russian adults
  • 2010
  • Ingår i: Journal of Russian and East European Psychology. - 1061-0405. ; 48:5, s. 5-35
  • Tidskriftsartikel (refereegranskat)abstract
    • The article investigates the connections between personality and intelligence and somatic and mental (externalizing) health disturbances in a sample of 752 Russian adults, who participated in the study during the societal turmoil of the 1990s. Given the degree of societal instability during that period, and the heightened rates of health problems, crime, and alcohol abuse, we hypothesized that the predictive links between personality and intelligence would be mediated by the perceived impact of the societal change and moderated by demographic variables such as gender, education, marital status, and age. The pattern of results differs for various outcome variables, but, in general, the results confirm, although only partially, the presence of both mediation and moderation by other variables in considering the connections between personality, intelligence, and somatic and mental health outcomes.
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47.
  • Haeffel, Gerald J., et al. (författare)
  • Association Between Polymorphisms in the Dopamine Transporter Gene and Depression : Evidence for a Gene-Environment Interaction in a Sample of Juvenile Detainees
  • 2008
  • Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 19:1, s. 62-69
  • Tidskriftsartikel (refereegranskat)abstract
    • Previous research has generated examples of how genetic and environmental factors can interact to create risk for psychopathology. Using a gene-by-environment (G × E) interaction design, we tested whether three polymorphisms in the dopamine transporter gene (DAT1, also referred to as SLC6A3, located at 5p15.33) interacted with maternal parenting style to predict first-onset episodes of depression. Participants were male adolescents (N= 176) recruited from a juvenile detention center in northern Russia. As hypothesized, one of the polymorphisms (rs40184) moderated the effect of perceived maternal rejection on the onset of major depressive disorder, as well as on suicidal ideation. Further, this G × E interaction was specific to depression; it did not predict clinically significant anxiety. These results highlight the need for further research investigating the moderating effects of dopaminergic genes on depression.
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48.
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49.
  • Isaksson, Johan, et al. (författare)
  • Exploring possible association between D beta H genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents
  • 2016
  • Ingår i: European Archives of Psychiatry and Clinical Neuroscience. - : Springer Science and Business Media LLC. - 0940-1334 .- 1433-8491. ; 266:8, s. 771-773
  • Tidskriftsartikel (refereegranskat)abstract
    • Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
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50.
  • Isaksson, Johan, et al. (författare)
  • Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents.
  • 2016
  • Ingår i: European Archives of Psychiatry and Clinical Neuroscience. - : Springer Science and Business Media LLC. - 0940-1334 .- 1433-8491. ; 266:8, s. 771-773
  • Tidskriftsartikel (refereegranskat)abstract
    • Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
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