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Sökning: WFRF:(Allentoft Morten E.)

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11.
  • Fischer, Anders, 1951, et al. (författare)
  • Vittrup Man-The life-history of a genetic foreigner in Neolithic Denmark.
  • 2024
  • Ingår i: PloS one. - 1932-6203. ; 19:2
  • Tidskriftsartikel (refereegranskat)abstract
    • The lethally maltreated body of Vittrup Man was deposited in a Danish bog, probably as part of a ritualised sacrifice. It happened between c. 3300 and 3100 cal years BC, i.e., during the period of the local farming-based Funnel Beaker Culture. In terms of skull morphological features, he differs from the majority of the contemporaneous farmers found in Denmark, and associates with hunter-gatherers, who inhabited Scandinavia during the previous millennia. His skeletal remains were selected for transdisciplinary analysis to reveal his life-history in terms of a population historical perspective. We report the combined results of an integrated set of genetic, isotopic, physical anthropological and archaeological analytical approaches. Strontium signature suggests a foreign birthplace that could be in Norway or Sweden. In addition, enamel oxygen isotope values indicate that as a child he lived in a colder climate, i.e., to the north of the regions inhabited by farmers. Genomic data in fact demonstrates that he is closely related to Mesolithic humans known from Norway and Sweden. Moreover, dietary stable isotope analyses on enamel and bone collagen demonstrate a fisher-hunter way of life in his childhood and a diet typical of farmers later on. Such a variable life-history is also reflected by proteomic analysis of hardened organic deposits on his teeth, indicating the consumption of forager food (seal, whale and marine fish) as well as farmer food (sheep/goat). From a dietary isotopic transect of one of his teeth it is shown that his transfer between societies of foragers and farmers took place near to the end of his teenage years.
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12.
  • Frei, Karin Margarita, et al. (författare)
  • Mapping human mobility during the third and second millennia BC in present-day Denmark
  • 2019
  • Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:8
  • Tidskriftsartikel (refereegranskat)abstract
    • We present results of the largest multidisciplinary human mobility investigation to date of skeletal remains from present-day Denmark encompassing the 3rd and 2nd millennia BC. Through a multi-analytical approach based on 88 individuals from 37 different archaeological localities in which we combine strontium isotope and radiocarbon analyses together with anthropological investigations, we explore whether there are significant changes in human mobility patterns during this period. Overall, our data suggest that mobility of people seems to have been continuous throughout the 3rd and 2nd millennia BC. However, our data also indicate a clear shift in mobility patterns from around 1600 BC onwards, with a larger variation in the geographical origin of the migrants, and potentially including more distant regions. This shift occurred during a transition period at the beginning of the Nordic Bronze Age at a time when society flourished, expanded and experienced an unprecedented economic growth, suggesting that these aspects were closely related.
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13.
  • Irving-Pease, Evan K., et al. (författare)
  • The selection landscape and genetic legacy of ancient Eurasians
  • 2024
  • Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 625, s. 312-320
  • Tidskriftsartikel (refereegranskat)abstract
    • The Holocene (beginning around 12,000 years ago) encompassed some of the most significant changes in human evolution, with far-reaching consequences for the dietary, physical and mental health of present-day populations. Using a dataset of more than 1,600 imputed ancient genomes 1, we modelled the selection landscape during the transition from hunting and gathering, to farming and pastoralism across West Eurasia. We identify key selection signals related to metabolism, including that selection at the FADS cluster began earlier than previously reported and that selection near the LCT locus predates the emergence of the lactase persistence allele by thousands of years. We also find strong selection in the HLA region, possibly due to increased exposure to pathogens during the Bronze Age. Using ancient individuals to infer local ancestry tracts in over 400,000 samples from the UK Biobank, we identify widespread differences in the distribution of Mesolithic, Neolithic and Bronze Age ancestries across Eurasia. By calculating ancestry-specific polygenic risk scores, we show that height differences between Northern and Southern Europe are associated with differential Steppe ancestry, rather than selection, and that risk alleles for mood-related phenotypes are enriched for Neolithic farmer ancestry, whereas risk alleles for diabetes and Alzheimer’s disease are enriched for Western hunter-gatherer ancestry. Our results indicate that ancient selection and migration were large contributors to the distribution of phenotypic diversity in present-day Europeans.
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14.
  • Kristiansen, Kristian, 1948, et al. (författare)
  • Gjerrild-graven – nyt fra dansk enkeltgravskultur
  • 2021
  • Ingår i: Skalk. - 0560-1894. ; 4, s. 3-7
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Gjerrild graven er den eneste grav med bevarede skeletter fra ENkeltgravskulturen (2800-2400 f.Kr.). Tre skeletter blev analyseret for DNA, og de viser steppe ancestry. De bekræfter således at Enkeltgravskulturen er indvandret som led i de omfattende Snorekeramiske migrationer
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15.
  • Kristiansen, Kristian, 1948, et al. (författare)
  • Re-theorising mobility and the formation of culture and language among the Corded Ware Culture in Europe
  • 2017
  • Ingår i: Antiquity. - : Antiquity Publications. - 0003-598X .- 1745-1744. ; 91:356, s. 334-347
  • Tidskriftsartikel (refereegranskat)abstract
    • Copyright © 2017 Antiquity Publications Ltd.Recent genetic, isotopic and linguistic research has dramatically changed our understanding of how the Corded Ware Culture in Europe was formed. Here the authors explain it in terms of local adaptations and interactions between migrant Yamnaya people from the Pontic-Caspian steppe and indigenous North European Neolithic cultures. The original herding economy of the Yamnaya migrants gradually gave way to new practices of crop cultivation, which led to the adoption of new words for those crops. The result of this hybridisation process was the formation of a new material culture, the Corded Ware Culture, and of a new dialect, Proto-Germanic. Despite a degree of hostility between expanding Corded Ware groups and indigenous Neolithic groups, stable isotope data suggest that exogamy provided a mechanism facilitating their integration. This article should be read in conjunction with that by Heyd (2017, in this issue).
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16.
  • Mühlemann, Barbara, et al. (författare)
  • Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age
  • 2020
  • Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 369:6502
  • Tidskriftsartikel (refereegranskat)abstract
    • Smallpox, one of the most devastating human diseases, killed between 300 million and 500 million people in the 20th century alone. We recovered viral sequences from 13 northern European individuals, including 11 dated to ~600-1050 CE, overlapping the Viking Age, and reconstructed near-complete variola virus genomes for four of them. The samples predate the earliest confirmed smallpox cases by ~1000 years, and the sequences reveal a now-extinct sister clade of the modern variola viruses that were in circulation before the eradication of smallpox. We date the most recent common ancestor of variola virus to ~1700 years ago. Distinct patterns of gene inactivation in the four near-complete sequences show that different evolutionary paths of genotypic host adaptation resulted in variola viruses that circulated widely among humans.
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17.
  • Redsted Rasmussen, Arne, et al. (författare)
  • Viviparous sea snakes can be used as bioindicators for diverse marine environments
  • 2020
  • Ingår i: Philippine Journal of Systematic Biology. - : Association of Systematic Biologists of the Philippines. - 1908-6865 .- 2508-0342. ; 14:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Shallow tropical marine ecosystems are under great anthropogenic pressure due to habitat destruction, overfishing,shrimping, climate change, and tourism. This is an issue of global concern as such environments hold a tremendousbiodiversity much of which remains to be described. The present situation urgently calls for time- and resource-efficientmethods to identify and delineate the most valuable remaining areas and to set up priorities for their management andconservation. Using indicator species can be a way to accomplish this goal. In this paper we evaluate whether viviparoussea snakes can serve as bioindicators for other rare or cryptic tropical marine fauna. Based on seven generallyacknowledged criteria for bioindicators, we argue that using viviparous sea snakes as bioindicators can help monitoringmarine habitats to gauge the effects of climate change, habitat change and loss, decline in biodiversity and otheranthropogenic changes. However, to maximize their efficacy as bioindicators, deeper knowledge about viviparous seasnakes natural history is urgently needed. Topics for expanded research programs include the taxonomy of some groups,their breeding and feeding biology, habitat selection and their geographical distribution. Despite these gaps in ourunderstanding, we argue that viviparous sea snakes can be utilized as bioindicators of marine ecosystem health.
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18.
  • Seersholm, Frederik Valeur, et al. (författare)
  • Repeated plague infections across six generations of Neolithic Farmers
  • 2024
  • Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 632:8023, s. 114-121
  • Tidskriftsartikel (refereegranskat)abstract
    • In the period between 5,300 and 4,900 calibratedyears before present (cal. bp), populations across large parts of Europe underwent a period of demographic decline1,2. However, the cause of this so-called Neolithic decline is still debated. Some argue for an agricultural crisis resulting in the decline3, others for the spread of an early form of plague4. Here we use population-scale ancient genomics to infer ancestry, social structure and pathogen infection in 108 Scandinavian Neolithic individuals from eight megalithic graves and a stone cist. We find that the Neolithic plague was widespread, detected in at least 17% of the sampled population and across large geographical distances. We demonstrate that the disease spread within the Neolithic community in three distinct infection events within a period of around 120 years. Variant graph-based pan-genomics shows that the Neolithic plague genomes retained ancestral genomic variation present in Yersinia pseudotuberculosis, including virulence factors associated with disease outcomes. In addition, we reconstruct four multigeneration pedigrees, the largest of which consists of 38 individuals spanning six generations, showing a patrilineal social organization. Lastly, we document direct genomic evidence for Neolithic female exogamy in a woman buried in a different megalithic tomb than her brothers. Taken together, our findings provide a detailed reconstruction of plague spread within a large patrilineal kinship group and identify multiple plague infections in a population dated to the beginning of the Neolithic decline.
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19.
  • Sjögren, Karl-Göran, 1949, et al. (författare)
  • Kinship and social organization in Copper Age Europe. A cross-disciplinary analysis of archaeology, DNA, isotopes, and anthropology from two Bell Beaker cemeteries.
  • 2020
  • Ingår i: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 15:11
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a high-resolution cross-disciplinary analysis of kinship structure and social institutions in two Late Copper Age Bell Beaker culture cemeteries of South Germany containing 24 and 18 burials, of which 34 provided genetic information. By combining archaeological, anthropological, genetic and isotopic evidence we are able to document the internal kinship and residency structure of the cemeteries and the socially organizing principles of these local communities. The buried individuals represent four to six generations of two family groups, one nuclear family at the Alburg cemetery, and one seemingly more extended at Irlbach. While likely monogamous, they practiced exogamy, as six out of eight non-locals are women. Maternal genetic diversity is high with 23 different mitochondrial haplotypes from 34 individuals, whereas all males belong to one single Y-chromosome haplogroup without any detectable contribution from Y-chromosomes typical of the farmers who had been the sole inhabitants of the region hundreds of years before. This provides evidence for the society being patrilocal, perhaps as a way of protecting property among the male line, while in-marriage from many different places secured social and political networks and prevented inbreeding. We also find evidence that the communities practiced selection for which of their children (aged 0-14 years) received a proper burial, as buried juveniles were in all but one case boys, suggesting the priority of young males in the cemeteries. This is plausibly linked to the exchange of foster children as part of an expansionist kinship system which is well attested from later Indo-European-speaking cultural groups.
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