↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Andreassen O) "

Sökning: WFRF:(Andreassen O)

Resultat 51-60 av 165

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
51.	Jami, E. S., et al. (författare) Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms 2022 Ingår i: Journal of the American Academy of Child and Adolescent Psychiatry. - : Elsevier BV. - 0890-8567 .- 1527-5418. ; 61:7, s. 934-945 Tidskriftsartikel (refereegranskat)abstract Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated assessments of internalizing symptoms, in a total of 64,561 children and adolescents between 3 and 18 years of age. Results were aggregated in meta-analyses that accounted for sample overlap, first using all available data, and then using subsets of measurements grouped by rater, age, and instrument. Results: The meta-analysis of overall internalizing symptoms (INToverall) detected no genome-wide significant hits and showed low single nucleotide polymorphism (SNP) heritability (1.66%, 95% CI = 0.84-2.48%, n(effective) = 132,260). Stratified analyses indicated rater-based heterogeneity in genetic effects, with self-reported internalizing symptoms showing the highest heritability (5.63%, 95% CI = 3.08%-8.18%). The contribution of additive genetic effects on internalizing symptoms appeared to be stable over age, with overlapping estimates of SNP heritability from early childhood to adolescence. Genetic correlations were observed with adult anxiety, depression, and the well-being spectrum (vertical bar r(g)vertical bar > 0.70), as well as with insomnia, loneliness, attention-deficit/hyperactivity disorder, autism, and childhood aggression (range vertical bar r(g)vertical bar = 0.42-0.60), whereas there were no robust associations with schizophrenia, bipolar disorder, obsessive-compulsive disorder, or anorexia nervosa. Conclusion: Genetic correlations indicate that childhood and adolescent internalizing symptoms share substantial genetic vulnerabilities with adult internalizing disorders and other childhood psychiatric traits, which could partially explain both the persistence of internalizing symptoms over time and the high comorbidity among childhood psychiatric traits. Reducing phenotypic heterogeneity in childhood samples will be key in paving the way to future GWAS success.
52.	Jiang, WH, et al. (författare) Surface Area Deficits in Schizophrenia: An ENIGMA Schizophrenia Working Group Meta-analysis 2016 Ingår i: BIOLOGICAL PSYCHIATRY. - 0006-3223. ; 79:9, s. 384S-384S Konferensbidrag (övrigt vetenskapligt/konstnärligt)
53.	Karlsson, R, et al. (författare) Investigation of six testicular germ cell tumor susceptibility genes suggests a parent-of-origin effect in SPRY4 2013 Ingår i: Human molecular genetics. - : Oxford University Press (OUP). - 1460-2083 .- 0964-6906. ; 22:16, s. 3373-3380 Tidskriftsartikel (refereegranskat)
54.	Kelly, S, et al. (författare) Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group 2018 Ingår i: Molecular psychiatry. - : Springer Science and Business Media LLC. - 1476-5578 .- 1359-4184. ; 23:5, s. 1261-1269 Tidskriftsartikel (refereegranskat)
55.	Kristiansen, W, et al. (författare) Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case-parent triad study in a Norwegian-Swedish population 2012 Ingår i: Human reproduction (Oxford, England). - : Oxford University Press (OUP). - 1460-2350 .- 0268-1161. ; 27:5, s. 1525-1535 Tidskriftsartikel (refereegranskat)
56.	Ousdal, O T, et al. (författare) The human amygdala is involved in general behavioral relevance detection : evidence from an event-related functional magnetic resonance imaging Go-NoGo task. 2008 Ingår i: Neuroscience. - 0306-4522 .- 1873-7544. ; 156:3, s. 450-455 Tidskriftsartikel (refereegranskat)abstract The amygdala is classically regarded as a detector of potential threat and as a critical component of the neural circuitry mediating conditioned fear responses. However, it has been reported that the human amygdala responds to multiple expressions of emotions as well as emotionally neutral stimuli of a novel, uncertain or ambiguous nature. Thus, it has been proposed that the function of the amygdala may be of a more general art, i.e. as a detector of behaviorally relevant stimuli [Sander D, Grafman J, Zalla T (2003) The human amygdala: an evolved system for relevance detection. Rev Neurosci 14:303-316]. To investigate this putative function of the amygdala, we used event related functional magnetic resonance imaging (fMRI) and a modified Go-NoGo task composed of behaviorally relevant and irrelevant letter and number stimuli. Analyses revealed bilateral amygdala activation in response to letter stimuli that were behaviorally relevant as compared with letters with less behavioral relevance. Similar results were obtained for relatively infrequent NoGo relevant stimuli as compared with more frequent Go stimuli. Our findings support a role for the human amygdala in general detection of behaviorally relevant stimuli.
57.	Pasman, J, et al. (författare) IS GENETIC RISK FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER ASSOCIATED WITH MORE SEVERE CLINICAL FEATURES THAN BROAD MAJOR DEPRESSIVE DISORDER? 2022 Ingår i: EUROPEAN NEUROPSYCHOPHARMACOLOGY. - : Elsevier BV. - 0924-977X. ; 63, s. E140-E140 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
58.	Ripke, S, et al. (författare) Biological insights from 108 schizophrenia-associated genetic loci 2014 Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 511:7510, s. 421- Tidskriftsartikel (refereegranskat)
59.	Ruderfer, DM, et al. (författare) Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes 2018 Ingår i: Cell. - : Elsevier BV. - 1097-4172 .- 0092-8674. ; 173:7, s. 1705- Tidskriftsartikel (refereegranskat)
60.	Stefansson, H, et al. (författare) Common variants conferring risk of schizophrenia 2009 Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 460:7256, s. 744-U99 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 51-60 av 165

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (146); konferensbidrag (17); forskningsöversikt (2)

Typ av innehåll: refereegranskat (138); övrigt vetenskapligt/konstnärligt (27)

Författare/redaktör: Andreassen, OA (69); Djurovic, S (59); Agartz, I (54); Melle, I (50); Werge, T (35); Cichon, S (35); visa fler...; Andreassen, O. A. (35); Jonsson, EG (34); Rujescu, D (33); Ripke, S (33); Stefansson, K (30); Stefansson, H. (30); Mattheisen, M (29); Rietschel, M (29); Corvin, A (28); Mors, O (26); MCDONALD, C (25); Ehrlich, S (24); Donohoe, G (24); Gill, M. (24); Nothen, MM (23); Steinberg, S (22); Landén, Mikael, 1966 (22); Ophoff, RA (22); Palotie, A (22); Herms, S. (22); Reif, A. (22); Breen, G (21); Dale, AM (21); McIntosh, AM (21); Muller-Myhsok, B (21); Craddock, N (20); Hoffmann, P (20); Le Hellard, S (20); Alda, M. (20); Westlye, LT (19); Mortensen, PB (19); Gruber, O (19); Martin, NG (19); Borglum, AD (19); Vieta, E (19); Mattingsdal, M (19); Sullivan, PF (18); Walton, E (18); Crespo-Facorro, B (18); Franke, B (18); Degenhardt, F (18); Esko, T (18); Metspalu, A (18); O'Donovan, MC (18); visa färre...

Lärosäte: Karolinska Institutet (145); Göteborgs universitet (38); Umeå universitet (27); Uppsala universitet (17); Lunds universitet (9); Stockholms universitet (6); visa fler...; Jönköping University (5); Örebro universitet (4); Högskolan Kristianstad (3); Chalmers tekniska högskola (2); Linköpings universitet (1); Södertörns högskola (1); Karlstads universitet (1); visa färre...

Språk: Engelska (165)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (72); Naturvetenskap (14); Teknik (2); Samhällsvetenskap (2)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy