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Träfflista för sökning "WFRF:(Borg A) "

Search: WFRF:(Borg A)

  • Result 21-30 of 571
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  • Coignard, J, et al. (author)
  • A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
  • 2021
  • In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1, s. 1078-
  • Journal article (peer-reviewed)abstract
    • Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies. Other mutation carrier-specific susceptibility variants may exist but studies of mutation carriers have so far been underpowered. We conduct a novel case-only genome-wide association study comparing genotype frequencies between 60,212 general population BC cases and 13,007 cases with BRCA1 or BRCA2 mutations. We identify robust novel associations for 2 variants with BC for BRCA1 and 3 for BRCA2 mutation carriers, P < 10−8, at 5 loci, which are not associated with risk in the general population. They include rs60882887 at 11p11.2 where MADD, SP11 and EIF1, genes previously implicated in BC biology, are predicted as potential targets. These findings will contribute towards customising BC polygenic risk scores for BRCA1 and BRCA2 mutation carriers.
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  • van de Sande-Bruinsma, Nienke, et al. (author)
  • Antimicrobial drug use and resistance in Europe
  • 2008
  • In: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6040 .- 1080-6059. ; 14:11, s. 1722-30
  • Journal article (peer-reviewed)abstract
    • Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000-2005 and explores whether the notion that antimicrobial drug use determines resistance can be supported by surveillance data at national aggregation levels. The data obtained from the European Surveillance of Antimicrobial Consumption and the European Antimicrobial Resistance Surveillance System suggest that variation of consumption coincides with the occurrence of resistance at the country level. Linear regression analysis showed that the association between antimicrobial drug use and resistance was specific and robust for 2 of 3 compound pathogen combinations, stable over time, but not sensitive enough to explain all of the observed variations. Ecologic studies based on routine surveillance data indicate a relation between use and resistance and support interventions designed to reduce antimicrobial drug consumption at a national level in Europe.
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  • Result 21-30 of 571
Type of publication
journal article (465)
conference paper (63)
book chapter (10)
research review (8)
other publication (7)
reports (6)
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book (4)
doctoral thesis (4)
editorial collection (2)
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Type of content
peer-reviewed (479)
other academic/artistic (82)
pop. science, debate, etc. (8)
Author/Editor
Borg, A (108)
Borg, Åke (103)
Borg, J. (49)
Olsson, Håkan (38)
Nevanlinna, H (36)
Radice, P (33)
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Hamann, U (31)
Easton, DF (31)
Borg, K (30)
Chenevix-Trench, G (29)
Peterlongo, P (28)
Manoukian, S (28)
Simard, J (28)
Borg, S. (28)
Thomassen, M. (28)
Andrulis, IL (27)
Antoniou, AC (27)
McGuffog, L. (27)
Neuhausen, SL (27)
Benitez, J. (26)
Schmutzler, RK (26)
Stoppa-Lyonnet, D. (26)
Montagna, M. (26)
Wappenschmidt, B. (26)
Couch, FJ (25)
Goldgar, DE (25)
Olah, E (25)
Rantala, J. (25)
Offit, K. (25)
Toland, AE (24)
Jakubowska, A (24)
Meindl, A (24)
Engel, C. (24)
Godwin, AK (24)
Domchek, SM (24)
Borg-Karlson, Anna-K ... (23)
Lubinski, J (23)
Staaf, Johan (23)
Karlan, BY (23)
Greene, MH (23)
Devilee, P (22)
Evans, DG (22)
Ringnér, Markus (22)
Singer, CF (22)
Osorio, A. (22)
Frost, D. (22)
Caldes, T. (22)
Barrowdale, D (22)
Caligo, MA (22)
Tischkowitz, M (22)
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University
Karolinska Institutet (238)
Lund University (199)
Uppsala University (114)
Royal Institute of Technology (37)
Södertörn University (36)
University of Gothenburg (31)
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Umeå University (29)
Stockholm University (27)
Linköping University (26)
Chalmers University of Technology (12)
Karlstad University (12)
Örebro University (8)
Linnaeus University (5)
Högskolan Dalarna (5)
Luleå University of Technology (4)
University of Gävle (2)
Jönköping University (2)
RISE (2)
Swedish University of Agricultural Sciences (2)
Halmstad University (1)
University West (1)
Mälardalen University (1)
Malmö University (1)
University College of Arts, Crafts and Design (1)
Stockholm School of Economics (1)
The Swedish School of Sport and Health Sciences (1)
Blekinge Institute of Technology (1)
Red Cross University College (1)
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Language
English (550)
Swedish (11)
Undefined language (5)
German (2)
Latin (2)
Danish (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (215)
Natural sciences (97)
Social Sciences (38)
Engineering and Technology (19)
Agricultural Sciences (3)
Humanities (2)

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