| 31. |
- Conroy, Sean W., et al.
(författare)
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Neutron spectrometer for ITER using silicon detectors
- 2008
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Ingår i: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 79:10, s. 10E508-
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Tidskriftsartikel (refereegranskat)abstract
- High resolution neutron spectrometers provide information about plasma parameters at existing fusion experiments. Such a system may also be employed at ITER. Proton recoil telescopes have classically been used to detect neutrons with good energy resolution but poor efficiency. Using annular silicon detectors, it is possible to greatly increase the solid angle coverage and hence improve efficiency. Based on a simulation (MCNPX) study, the scaling of energy resolution, efficiency, and time to determine an ion temperature to 10% accuracy on foil thickness and detector location is shown. The latter quantity is used to determine the optimum foil thickness and detector geometry for specific plasma temperatures. For a 20 keV deuterium-tritium (DT) plasma, 5.3% resolution with efficiency of 2.9x10(-4) n cm(2) is attainable using the available detectors. This gives a temperature measurement with 10% accuracy in 1.1 ms for a neutron flux of 2x10(9) n cm(-2). Multiple detectors can be used to further increase the efficiency if needed. A system of this kind could be tested in a future DT campaign at, for example, JET.
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| 32. |
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| 33. |
- Darmanis, Spyros, et al.
(författare)
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Sensitive plasma protein analysis by microparticle-based proximity ligation assays
- 2010
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Ingår i: Molecular & Cellular Proteomics. - 1535-9476 .- 1535-9484. ; 9:2, s. 327-335
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Tidskriftsartikel (refereegranskat)abstract
- Detection of proteins released in the bloodstream from tissues damaged by disease can promote early detection of pathological conditions, differential diagnostics, and follow-up of therapy. Despite these prospects and a plethora of candidate biomarkers, efforts in recent years to establish new protein diagnostic assays have met with limited success. One important limiting factor has been the challenge of detecting proteins present at trace levels in complex bodily fluids. To achieve robust, sensitive, and specific detection, we have developed a microparticle-based solid-phase proximity ligation assay, dependent on simultaneous recognition of target proteins by three antibody molecules for added specificity. After capture on a microparticle, solid-phase pairs of proximity probes are added followed by washes, enabling detection and identification of rare protein molecules in blood while consuming small amounts of sample. We demonstrate that single polyclonal antibody preparations raised against target proteins of interest can be readily used to establish assays where detection depends on target recognition by three individual antibody molecules, recognizing separate epitopes. The assay was compared with state-of-the-art sandwich ELISAs for detection of vascular endothelial growth factor, interleukin-8 and interleukin-6, and it was found to be superior both with regard to dynamic range and minimal numbers of molecules detected. Furthermore, the assays exhibited excellent performance in undiluted plasma and serum as well as in whole blood, producing comparable results for nine different antigens. We thus show that solid-phase proximity ligation assay is suitable for validation of a variety of protein biomarkers over broad dynamic ranges in clinical samples.
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| 34. |
- Dorell, Åsa, et al.
(författare)
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Experiences With Family Health Conversations at Residential Homes for Older People
- 2016
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Ingår i: Clinical Nursing Research. - : SAGE Publications. - 1054-7738 .- 1552-3799. ; 25:5, s. 560-582
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to highlight family members' experiences of participating in Family Health Conversation (FamHC), based on families in which a family member was living in a residential home for older people. A total of 10 families and 22 family members participated in evaluating family interviews 1 month after participating in FamHC. The interviews were analyzed by qualitative content analysis. The main finding was being a part of FamHC increased family members' insights, understanding, and communication within the family. Getting confirmation from nurses was essential to cope with the new life situation, which also meant that they felt comfortable to partly hand over the responsibility for the older person who moved to the residential home. By being open and expressing their feelings, a bad conscience could be relieved. These findings showed that FamHC could be helpful for family members in adapting to this novel situation.
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| 35. |
- Dressel, Sabrina, et al.
(författare)
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Achieving Social and Ecological Outcomes in Collaborative Environmental Governance : Good Examples from Swedish Moose Management
- 2021
-
Ingår i: Sustainability. - : MDPI. - 2071-1050. ; 13:4
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Tidskriftsartikel (refereegranskat)abstract
- Collaborative governance approaches have been suggested as strategies to handle wicked environmental problems. Evaluations have found promising examples of effective natural resource governance, but also highlighted the importance of social-ecological context and institutional design. The aim of this study was to identify factors that contribute to the achievement of social and ecological sustainability within Swedish moose (Alces alces) management. In 2012, a multi-level collaborative governance regime was implemented to decrease conflicts among stakeholders. We carried out semi-structured interviews with six ‘good examples’ (i.e., Moose Management Groups that showed positive social and ecological outcomes). We found that ‘good examples’ collectively identified existing knowledge gaps and management challenges and used their discretionary power to develop procedural arrangements that are adapted to the social-ecological context, their theory of change, and attributes of local actors. This contributed to the creation of bridging social capital and principled engagement across governance levels. Thus, our results indicate the existence of higher-order social learning as well as a positive feedback from within-level collaboration dynamics to between-level collaboration. Furthermore, our study illustrates the importance of institutional flexibility to utilize the existing knowledge across stakeholder groups and to allow for adaptations based on the social learning process.
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| 36. |
- Dressel, Sabrina, et al.
(författare)
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Perceived adaptive capacity within a multi-level governance setting : The role of bonding, bridging, and linking social capital
- 2020
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Ingår i: Environmental Science and Policy. - : Elsevier. - 1462-9011 .- 1873-6416. ; 104, s. 88-97
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Tidskriftsartikel (refereegranskat)abstract
- In 2012 Sweden implemented a collaborative governance regime for managing moose (Alces alces). This was guided by the awareness that decentralization and stakeholder participation can help to reduce conflicts, foster systematic learning, and handle complexity. However, previous research has highlighted that there are no blueprint approaches to the governance and management of natural resources. In this case, diverse multi-use landscapes, ever-changing ungulate populations, and other external stressors (e.g. climate change, wildlife diseases) can create challenges for collaborative institutions. Adaptive capacity is therefore needed as it allows a system and the actors involved to react successfully to social-ecological changes and to develop even in times of no imminent change or risk. Using Swedish moose management as an example of a multi-level governance system, this research assesses the critical determinants of adaptive capacity across levels. We developed and applied a psychometric approach to measure actors’ perceived adaptive capacity on two levels in the management system. A web-based survey was sent to Moose Management Groups (n = 765, response rate = 81 %) and Moose Management Units (n = 1,380, response rate = 71 %). Using structural equation modelling, we assessed the relative importance of governance aspects, different types of social capital, as well as human and financial capital on actors’ perceived adaptive capacity. Linking and bridging social capital in the system had significant impacts on both levels. Actors felt more prepared to handle future challenges in moose management when they perceived benefits through collaborations with levels below and expressed social trust in authorities and the management level above. Besides those similarities between the two levels, fairness was a more important determinant of actors’ perceived adaptive capacity on the lower management level. These results can contribute to a future improvement of the collaborative governance setting by finessing strategic interventions on different levels. Furthermore, our results illustrate the importance of scale when assessing the adaptive capacity of a system.
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| 37. |
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| 38. |
- Ericsson, Fredrik, et al.
(författare)
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Forskare positiv till utomhuslektioner – men varnar för att romantisera
- 2019
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Ingår i: Södermanlands Nyheter. ; 2019-02-15
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Ingress: Att utomhuspedagogik kan vara bra för både inlärningen och motion ifrågasätter inte en forskare i utomhuspedagogik vid högskolan i Jönköping. Men hon varnar också:– Vi har en tradition av Bullerbyn och Astrid Lindgren-värld. Vi romantiserar allt som är utomhus, ibland kan det vara dumt att gå ut, säger doktorand Maria Hammarsten.
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| 39. |
- Ericsson, Leif, 1964-, et al.
(författare)
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An experimental setup for dip-coating of thin films for organic solar cells under microgravity conditions
- 2021
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Ingår i: Review of Scientific Instruments. - : American Institute of Physics (AIP). - 0034-6748 .- 1089-7623. ; 92:1
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Tidskriftsartikel (refereegranskat)abstract
- We report the design and testing of a custom-built experimental setup for dip-coating from volatile solutions under microgravity conditionsonboard an aircraft. Function and safety considerations for the equipment are described. The equipment proved to work well, both concerningthe safety and the preparation of thin films. No leakage of the solvents, nor the solvent vapors, was detected, not even in a situation with afluctuating gravitational field due to bad weather conditions. We have shown that the equipment can be used to prepare thin films of polymerblends, relevant for organic solar cells, from solution in a feasible procedure under microgravity conditions. The prepared films are similar tothe corresponding films prepared under 1 g conditions, but with differences that can be related to the absence of a gravitational field duringdrying of the applied liquid coating. We report on some introductory results from the characterization of the thin films that show differencesin film morphology and structure sizes.
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| 40. |
- Ericsson, Leon, et al.
(författare)
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Generalized super-resolution 4D Flow MRI - using ensemble learning to extend across the cardiovascular system
- 2024
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Ingår i: IEEE journal of biomedical and health informatics. - 2168-2194 .- 2168-2208. ; , s. 1-12
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Tidskriftsartikel (refereegranskat)abstract
- 4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation of trained super-resolution (SR) networks has potential to enhance image quality post-scan. However, these efforts have predominantly been restricted to narrowly defined cardiovascular domains, with limited exploration of how SR performance extends across the cardiovascular system; a task aggravated by contrasting hemodynamic conditions apparent across the cardiovasculature. The aim of our study was therefore to explore the generalizability of SR 4D Flow MRI using a combination of existing super-resolution base models, novel heterogeneous training sets, and dedicated ensemble learning techniques; the latter-most being effectively used for improved domain adaption in other domains or modalities, however, with no previous exploration in the setting of 4D Flow MRI. With synthetic training data generated across three disparate domains (cardiac, aortic, cerebrovascular), varying convolutional base and ensemble learners were evaluated as a function of domain and architecture, quantifying performance on both in-silico and acquired in-vivo data from the same three domains. Results show that both bagging and stacking ensembling enhance SR performance across domains, accurately predicting high-resolution velocities from low-resolution input data in-silico. Likewise, optimized networks successfully recover native resolution velocities from downsampled in-vivo data, as well as show qualitative potential in generating denoised SR-images from clinicallevel input data. In conclusion, our work presents a viable approach for generalized SR 4D Flow MRI, with the novel use of ensemble learning in the setting of advanced fullfield flow imaging extending utility across various clinical areas of interest.
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