| 11. |
- Stolk, Lisette, et al.
(författare)
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Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
- 2012
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:3, s. 260-268
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Tidskriftsartikel (refereegranskat)abstract
- To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wide association studies (GWAS) in 38,968 women of European descent, with replication in up to 14,435 women. In addition to four known loci, we identified 13 loci newly associated with age at natural menopause (at P < 5 × 10(-8)). Candidate genes located at these newly associated loci include genes implicated in DNA repair (EXO1, HELQ, UIMC1, FAM175A, FANCI, TLK1, POLG and PRIM1) and immune function (IL11, NLRP11 and PRRC2A (also known as BAT2)). Gene-set enrichment pathway analyses using the full GWAS data set identified exoDNase, NF-κB signaling and mitochondrial dysfunction as biological processes related to timing of menopause.
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| 12. |
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| 13. |
- Lozeva, R. L., et al.
(författare)
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New sub-us Isomers in 125Sn, 127Sn, 129Sn and Isomer Systematics of 124-130Sn
- 2008
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 77:6
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Tidskriftsartikel (refereegranskat)abstract
- New sub-mu s isomers have been observed in the neutron-rich Sn isotopes. Sn-125,Sn-127,Sn-129 nuclei have been produced in a relativistic fission reaction of U-238 on a Be-9 target at 750 A.MeV and by the fragmentation of Xe-136 at 600 A.MeV populating high-spin yrast states. In addition to the already known mu s isomers, three new ones with sub-mu s half-lives have been observed. These yrast isomers are the high-spin members of the nu(d(3/2)(-1)h(11/2)(-2)) and nu h(11/2)(-n), seniority v = 3 multiplets leading to isomeric (23/2(+)) and (27/2(-)) states, respectively. Added to the already known 19/2(+)mu s isomers in this region the current work completes the systematic information of neutron-hole excitations toward the filling of the last h(11/2) orbital at N = 82. The results are discussed in the framework of state-of-the-art shell-model calculations using realistic interactions.
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| 14. |
- Neyens, G., et al.
(författare)
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g-Factor Measurements on Relativistic Isomeric Beams Produced by Fragmentation and U-fission: The g-RISING Project at GSI
- 2007
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Ingår i: Acta Physica Polonica. Series B: Elementary Particle Physics, Nuclear Physics, Statistical Physics, Theory of Relativity, Field Theory. - 0587-4254. ; 38:4, s. 1237-1247
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Tidskriftsartikel (refereegranskat)abstract
- Within the RISING (Rare ISotope INvestigations @ GSI) Collaboration at GSI, g factor measurements have been performed on isomeric states in neutron-rich isotopes approaching Sn-132 and in the neutron deficient Pb-region (the g-RISING campaign). We present the experimental technique and some typical aspects related to such studies on relativistic beams selected with the FRS fragment separator. First results are presented for the (19/2(+)) 4.5 mu s isomeric state in Sn-127, which has been produced by means of fission of a relativistic U-238 beam on the one hand, and by the fragmentation of a relativistic Xe-136 beam on the other hand. Spin-alignment has been observed in both reactions. It was the first time that spin-alignment has been established in a relativistic fission reaction.
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| 15. |
- Atanasova, L., et al.
(författare)
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g-factor Measurements at RISING: The Cases of 127Sn and 128Sn
- 2010
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Ingår i: Europhysics Letters. - : IOP Publishing. - 0295-5075. ; 91:4
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Tidskriftsartikel (refereegranskat)abstract
- We report on g-factor measurements of the 19/2(+) T-1/2 = 4.5(3) mu s isomer in Sn-127 and the 10(+) T-1/2 = 2.69(23) mu s isomer in Sn-128. These isomers were produced and spin-aligned in relativistic heavy-ion fragmentation at GSI and were selected and separated by the GSI fragment separator ( FRS). The gamma-rays of the isomeric decay were detected by the RISING gamma-ray spectrometer. The method of time-differential perturbed angular distributions was utilized. The measured g-factors, g(19/2(+); Sn-127) =-0.17(2) and g(10(+); Sn-128)=-0.20(4), are compared with shell model calculations. The measured g-factors confirm the predominantly nu h(11/2)(-2) and nu(s(1/2)(-1) h(11/2)(-2)) character of the 10(+) and 19/2(-) isomers in Sn-128 and Sn-127, respectively. The results demonstrate the feasibility of the method for similar measurements in exotic neutron-rich nuclei. Copyright (C) EPLA, 2010
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| 16. |
- Gaffney, L. P., et al.
(författare)
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Collectivity in the light radon nuclei measured directly via Coulomb excitation
- 2015
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:6
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Tidskriftsartikel (refereegranskat)abstract
- Background: Shape coexistence in heavy nuclei poses a strong challenge to state-of-the-art nuclear models, where several competing shape minima are found close to the ground state. A classic region for investigating this phenomenon is in the region around Z = 82 and the neutron midshell at N = 104. Purpose: Evidence for shape coexistence has been inferred from a-decay measurements, laser spectroscopy, and in-beam measurements. While the latter allow the pattern of excited states and rotational band structures to be mapped out, a detailed understanding of shape coexistence can only come from measurements of electromagnetic matrix elements. Method: Secondary, radioactive ion beams of Rn-202 and Rn-204 were studied by means of low-energy Coulomb excitation at the REX-ISOLDE in CERN. Results: The electric-quadrupole (E2) matrix element connecting the ground state and first excited 2(1)(+) state was extracted for both Rn-202 and Rn-204, corresponding to B(E2; 2(1)(+) -> 0(1)(+)) = 29(-8)(+8) and 43(-12)(+17) W.u., respectively. Additionally, E2 matrix elements connecting the 2(1)(+) state with the 4(1)(+) and 2(2)(+) states were determined in Rn-202. No excited 0(+) states were observed in the current data set, possibly owing to a limited population of second-order processes at the currently available beam energies. Conclusions: The results are discussed in terms of collectivity and the deformation of both nuclei studied is deduced to be weak, as expected from the low-lying level-energy schemes. Comparisons are also made to state-of-the-art beyond-mean-field model calculations and the magnitude of the transitional quadrupole moments are well reproduced.
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| 17. |
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| 18. |
- Kmiecik, M., et al.
(författare)
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Spin-alignment and g-factor Measurement of the I=12+ Isomer in 192Pb Produced in the Relativistic-energy Fragmentation of a 238U Beam
- 2010
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Ingår i: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 45:2, s. 153-158
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Tidskriftsartikel (refereegranskat)abstract
- The feasibility of measuring g-factors using the TDPAD method applied to high-energy, heavy fragmentation products is explored. The 2623 keV I-pi = 12(+) isomer in Pb-192 with tau = 1.57 mu s has been produced using the fragmentation of a 1 A GeV U-238 beam. The results presented demonstrate for the first time that such heavy nuclei produced in a fragmentation reaction with a relativistic beam are sufficiently well spin-aligned. Moreover, the rather large value of the alignment, 28(10)% of the maximum possible, is preserved during the separation process allowing the determination of magnetic moments. The measured values of the lifetime, tau = 1.54(9) mu s, and the g-factor, g = -0.175(20), agree with the results of previous investigations using fusion-evaporation reactions.
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| 19. |
- Lechner, C., et al.
(författare)
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First direct seeding at 38 nm
- 2012
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Ingår i: FEL 2012 - 34th International Free Electron Laser Conference. - 9783954501236 ; , s. 197-199
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The sFLASH project at DESY is an experiment to study direct seeding using a source based on the high-harmonic generation (HHG) process. In contrast to SASE, a seeded FEL exhibits greatly improved longitudinal coherence and higher shot-to-shot stability (both spectral and energetic). In addition, the output of the seeded FEL is intrinsically synchronized to the HHG drive laser, thus enabling pump-probe experiments with a resolution of the order of 10 fs. The installation and successful commissioning of the sFLASH components in 2010/2011 has been followed by a planned upgrade in autumn 2011. As a result of these improvements, in spring 2012 direct HHG seeding at 38 nm has been successfully demonstrated. In this contribution, we describe the experimental layout and announce the first seeding at 38 nm.
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| 20. |
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