SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Hedlin G.) "

Search: WFRF:(Hedlin G.)

  • Result 171-180 of 275
Sort/group result
   
EnumerationReferenceCoverFind
171.
  •  
172.
  •  
173.
  •  
174.
  •  
175.
  • Hedlin, G, et al. (author)
  • The role of immunotherapy in the management of childhood asthma
  • 2012
  • In: Therapeutic advances in respiratory disease. - : SAGE Publications. - 1753-4666. ; 6:3, s. 137-146
  • Journal article (peer-reviewed)abstract
    • Subcutaneous immunotherapy (SCIT) is still questioned as a safe and efficacious way of treating allergic asthma in children. In a Cochrane review published in 2010 it was, however, concluded that SCIT has significant and beneficial effects on symptoms and medication use in both children and adults with mostly mild asthma. Only a few studies have been performed to specifically study if SCIT in children with moderate asthma reduces the need for inhaled corticosteroids. There are conflicting results that illustrate the problem of the heterogeneity of the asthma disease and the fact that allergies may play different roles on the severity and symptoms of the disease. Furthermore, children with severe allergic asthma are often sensitized to multiple allergens, which makes SCIT both complicated and less safe to administer. On the other hand, if the child suffers from asthmatic symptoms despite adherence to pharmacotherapy, omalizumab or a combination of omalizumab and allergen immunotherapy might be useful. There is a need for more studies on this combination before it can be considered as an additional therapy in children with asthma and severe allergies. Sublingual immunotherapy (SLIT) has also been shown to improve asthma symptoms and medication use. SLIT is safe although its efficacy compared with SCIT has been studied very little. Another approach is to try to prevent asthma by treating children with SCIT for allergic rhinoconjunctivitis before asthma has developed. The most attractive prospect, however, is to find ways of preventing asthma by vaccination against the most common viruses, particularly rhinovirus. There is evidence that there are children at high risk of developing asthma in whom a viral infection can also enhance the risk of allergen sensitization. So far this vaccination has not been achievable although research is in progress.
  •  
176.
  •  
177.
  •  
178.
  •  
179.
  • Henckel, E., et al. (author)
  • Telomere length was similar in school-age children with bronchopulmonary dysplasia and allergic asthma
  • 2018
  • In: Acta Paediatrica. - : John Wiley & Sons. - 0803-5253 .- 1651-2227. ; 107:8, s. 1395-1401
  • Journal article (peer-reviewed)abstract
    • Aim: Inflammation is a major factor in the pathophysiology of bronchopulmonary dysplasia (BPD), and it contributes to accelerated telomere shortening and cellular ageing. This study aimed to determine its effect on telomere length and lung function in school-aged children born preterm with BPD.Methods: We examined 29 children with BPD, born preterm in Stockholm county 1998-99, along with 28 children with allergic asthma born at term matched for age and gender. At 10 years of age, we measured relative telomere length (RTL) in blood by quantitative polymerase chain reaction, lung function by spirometry and inflammation by fractional exhaled nitric oxide and blood cytokines.Results: RTL was not different in preterm born with BPD compared to term born children with asthma. The gender effect was strong in both groups; girls had significantly longer median RTL than boys (1.8 versus 1.5, p < 0.01). Short RTL was associated with low forced expiratory flow, also after adjusting for gender, but was not affected by severity of BPD or ongoing inflammation.Conclusion: Telomere length was similar in 10-year-old children born preterm with a history of BPD and term born children with allergic asthma. However, impaired lung function and male gender were associated wrth short telomeres.
  •  
180.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 171-180 of 275
Type of publication
journal article (202)
conference paper (67)
book chapter (4)
book (1)
review (1)
Type of content
peer-reviewed (172)
other academic/artistic (101)
pop. science, debate, etc. (2)
Author/Editor
Hedlin, G (269)
Nordlund, B (93)
Soderhall, C (51)
Konradsen, JR (37)
Skjerven, HO (37)
Vettukattil, R (37)
show more...
Carlsen, KCL (36)
van Hage, M (35)
Jonassen, CM (33)
Staff, AC (33)
Rehbinder, EM (32)
Bush, A (27)
Roberts, G (26)
Rudi, K (26)
Hashimoto, S (23)
Singer, F (23)
Carlsen, KH (23)
Frey, U (22)
Dahlen, SE (21)
Melen, E (21)
Djukanovic, R (20)
Chung, KF (20)
Bisgaard, H (20)
Wickman, M (20)
Asarnoj, A (20)
Sterk, PJ (19)
Lilja, G (18)
Konradsen, J (18)
Gronlund, H (17)
Kull, I (17)
Fowler, SJ (16)
Dahlen, B (16)
Gudmundsdóttir, HK (15)
Sousa, AR (14)
Corfield, J (14)
Pedroletti, C (14)
Auffray, C (13)
Murray, CS (13)
Pershagen, G (13)
Bains, KES (13)
James, A. (12)
Fleming, LJ (12)
Bansal, AT (12)
Bonnelykke, K (12)
Wennergren, Göran, 1 ... (12)
LeBlanc, M (11)
Adcock, IM (11)
Valenta, R (11)
Ostblom, E (11)
Nordhagen, LS (11)
show less...
University
Karolinska Institutet (256)
Uppsala University (21)
University of Gothenburg (19)
Umeå University (8)
Karlstad University (6)
Royal Institute of Technology (3)
show more...
Lund University (2)
Stockholm University (1)
Red Cross University College (1)
show less...
Language
English (269)
Swedish (6)
Research subject (UKÄ/SCB)
Medical and Health Sciences (41)
Natural sciences (2)
Social Sciences (2)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view