| 451. |
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| 452. |
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| 453. |
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| 454. |
- Peeters, LM, et al.
(författare)
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COVID-19 in people with multiple sclerosis: A global data sharing initiative
- 2020
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Ingår i: Multiple sclerosis (Houndmills, Basingstoke, England). - : SAGE Publications. - 1477-0970 .- 1352-4585. ; 26:10, s. 1157-1162
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Tidskriftsartikel (refereegranskat)abstract
- We need high-quality data to assess the determinants for COVID-19 severity in people with MS (PwMS). Several studies have recently emerged but there is great benefit in aligning data collection efforts at a global scale. Objectives: Our mission is to scale-up COVID-19 data collection efforts and provide the MS community with data-driven insights as soon as possible. Methods: Numerous stakeholders were brought together. Small dedicated interdisciplinary task forces were created to speed-up the formulation of the study design and work plan. First step was to agree upon a COVID-19 MS core data set. Second, we worked on providing a user-friendly and rapid pipeline to share COVID-19 data at a global scale. Results: The COVID-19 MS core data set was agreed within 48 hours. To date, 23 data collection partners are involved and the first data imports have been performed successfully. Data processing and analysis is an on-going process. Conclusions: We reached a consensus on a core data set and established data sharing processes with multiple partners to address an urgent need for information to guide clinical practice. First results show that partners are motivated to share data to attain the ultimate joint goal: better understand the effect of COVID-19 in PwMS.
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| 455. |
- Samoilenko, D, et al.
(författare)
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Discussion on CSR instability in EEHG Simulation
- 2021
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Ingår i: Proceedings of IPAC2021.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Echo-Enabled Harmonic Generation (EEHG) is an external seeding technique for XUV and soft X-ray Free Electron Lasers (FEL). It has recently been experimentally demonstrated and currently many facilities worldwide intend to incorporate it in user operation. The EEHG process relies on very accurate and complex transformations of electron beam phase space by means of a series of undulators coupled to lasers and dispersive chicanes. As a result of the phase space manipulation, electrons are bunched at a high harmonic of the seed laser wavelength allowing coherent emission at few nm wavelength.
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| 456. |
- Samoilenko, D, et al.
(författare)
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Sensitivity of EEHG simulations to dynamic beam parameters
- 2023
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Ingår i: 13th International Particle Accelerator Conference (IPAC'22) 12 - 17 June 2022, Bangkok, Thailand. - : IOP Publishing. - 1742-6588. ; 2420
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Konferensbidrag (refereegranskat)abstract
- Currently, the Free electron laser user facility FLASH at DESY is undergoing a significant upgrade involving the complete transformation of one of its beamlines to allow external seeding. With the Echo-Enabled Harmonic Generation (EEHG) seeding method, we aim for the generation of fully coherent XUV and soft X-ray pulses at wavelengths down to 4 nm. The generated FEL radiation is sensitive to various electron beam properties, e.g., its energy profile imprinted either deliberately or by collective effects such as Coherent Synchrotron Radiation (CSR). In dedicated particle tracking simulations, one usually makes certain assumptions concerning the beam properties and the collective effects to simplify implementation and analysis. Here, we estimate the influence of some of the common assumptions made in EEHG simulations on the properties of the output FEL radiation, using the example of FLASH and its proposed seeding beamline. We conclude that the inherent properties of the FLASH1 beam, namely the negatively chirped energy profile, has dominant effect on the spectral intensity profile of the radiators output compare to that of the CSR induced chirp.
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