SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Hoekstra Pieter J.) "

Search: WFRF:(Hoekstra Pieter J.)

  • Result 11-12 of 12
Sort/group result
   
EnumerationReferenceCoverFind
11.
  • Danad, Ibrahim, et al. (author)
  • Coronary risk factors and myocardial blood flow in patients evaluated for coronary artery disease : a quantitative [15O]H2O PET/CT study
  • 2012
  • In: European Journal of Nuclear Medicine and Molecular Imaging. - : Springer Science and Business Media LLC. - 1619-7070 .- 1619-7089. ; 39:1, s. 102-112
  • Journal article (peer-reviewed)abstract
    • BackgroundThere has been increasing interest in quantitative myocardial blood flow (MBF) imaging over the last years and it is expected to become a routinely used technique in clinical practice. Positron emission tomography (PET) using [15O]H2O is the established gold standard for quantification of MBF in vivo. A fundamental issue when performing quantitative MBF imaging is to define the limits of MBF in a clinically suitable population. The aims of the present study were to determine the limits of MBF and to determine the relationship among coronary artery disease (CAD) risk factors, gender and MBF in a predominantly symptomatic patient cohort without significant CAD.MethodsA total of 128 patients (mean age 54 ± 10 years, 50 men) with a low to intermediate pretest likelihood of CAD were referred for noninvasive evaluation of CAD using a hybrid PET/computed tomography (PET/CT) scanner. MBF was quantified with [15O]H2O at rest and during adenosine-induced hyperaemia. Obstructive CAD was excluded in these patients by means of invasive or CT-based coronary angiography.ResultsGlobal average baseline MBF values were 0.91 ± 0.34 and 1.09 ± 0.30  ml·min−1·g−1 (range 0.54–2.35  and 0.59–2.75 ml·min−1·g−1) in men and women, respectively (p < 0.01). However, no gender-dependent difference in baseline MBF was seen following correction for rate–pressure product (0.98 ± 0.45 and 1.09 ± 0.30 ml·min−1·g−1 in men and women, respectively; p = 0.08). Global average hyperaemic MBF values were 3.44 ± 1.20 ml·min−1·g−1 in the whole study population, and 2.90 ± 0.85 and 3.78 ± 1.27 ml·min−1·g−1 (range 1.52–5.22 and 1.72–8.15 ml·min−1·g−1) in men and women, respectively (p < 0.001). Multivariate analysis identified male gender, age and body mass index as having an independently negative impact on hyperaemic MBF.ConclusionGender, age and body mass index substantially influence reference values and should be corrected for when interpreting hyperaemic MBF values.
  •  
12.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 11-12 of 12
Type of publication
journal article (11)
research review (1)
Type of content
peer-reviewed (11)
other academic/artistic (1)
Author/Editor
Franke, Barbara (8)
Agartz, Ingrid (8)
Westlye, Lars T (8)
Andreassen, Ole A (7)
Espeseth, Thomas (7)
Ching, Christopher R ... (6)
show more...
Brouwer, Rachel M (6)
Thompson, Paul M (6)
de Geus, Eco J. C. (6)
Martin, Nicholas G. (6)
Boomsma, Dorret I. (6)
Meyer-Lindenberg, An ... (6)
Nyberg, Lars, 1966- (6)
Jahanshad, Neda (6)
Veltman, Dick J (6)
Sachdev, Perminder S ... (6)
Wittfeld, Katharina (6)
Wright, Margaret J. (6)
de Zubicaray, Greig ... (6)
Ehrlich, Stefan (6)
Fisher, Simon E. (6)
Holmes, Avram J. (6)
McMahon, Katie L. (6)
Wen, Wei (6)
Buitelaar, Jan K (6)
Smoller, Jordan W (6)
Alnæs, Dag (5)
Cannon, Dara M (5)
McDonald, Colm (5)
Melle, Ingrid (5)
Wang, Lei (5)
Heslenfeld, Dirk J. (5)
van der Meer, Dennis (5)
Bertolino, Alessandr ... (5)
Djurovic, Srdjan (5)
Doan, Nhat Trung (5)
Pergola, Giulio (5)
Heinz, Andreas (5)
Hartman, Catharina A ... (5)
Crespo-Facorro, Bene ... (5)
Tordesillas-Gutierre ... (5)
Medland, Sarah E (5)
Schmaal, Lianne (5)
Schumann, Gunter (5)
Brodaty, Henry (5)
Buckner, Randy L. (5)
Glahn, David C. (5)
Strike, Lachlan T. (5)
van Haren, Neeltje E ... (5)
Hibar, Derrek P. (5)
show less...
University
Umeå University (8)
Uppsala University (8)
Karolinska Institutet (7)
University of Gothenburg (2)
Stockholm University (1)
Language
English (12)
Research subject (UKÄ/SCB)
Medical and Health Sciences (11)
Natural sciences (1)
Social Sciences (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view