SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Johansson Anders) "

Sökning: WFRF:(Johansson Anders)

  • Resultat 51-60 av 4186
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
51.
  •  
52.
  • Rydh, Anders, et al. (författare)
  • Radioimmunotherapy of DU-145 tumours in nude mice--a pilot study with E4, a novel monoclonal antibody against prostate cancer.
  • 1999
  • Ingår i: Acta Oncologica. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 38:8, s. 1075-1079
  • Tidskriftsartikel (refereegranskat)abstract
    • The anti-tumour effect of the 131I-labelled antiprostate monoclonal antibody (MAb) E4 was studied in an experimental model with 41 nude mice, subcutaneously xenografted with a human prostate cancer cell line (DU-145). The mice were divided into four study groups, i.e. one receiving single and another repeated injections of the radiolabelled MAb. A third group was injected with non-labelled MAb, and the fourth served as an untreated control group. The tumour volumes increased similarly in all groups during the 27-day observation period. The tumour tissue was morphologically disintegrated in the group that received repeated radioimmunotherapy (RIT). The tumours from this group contained large fluid-filled cystic parts and demonstrated pronounced cellular and subcellular polymorphism in the remaining viable tumour tissue. The untreated control tumours and single therapy tumours remained solid. The proportion of the total tumour volume that consisted of viable tumour cells, as determined by morphometric techniques, was significantly lower in the 131I-E4-treated groups. The use of 131I-labelled E4 MAb has thus demonstrated a promising therapeutic potential.
  •  
53.
  •  
54.
  • Sundh, Josefin, 1972-, et al. (författare)
  • Beta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE) - Study protocol from a randomized controlled trial
  • 2020
  • Ingår i: Trials. - : BioMed Central (BMC). - 1745-6215. ; 21:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Observational studies indicate that beta-blockers are associated with a reduced risk of exacerbation and mortality in patients with chronic obstructive pulmonary disease (COPD) even without overt cardiovascular disease, but data from randomized controlled trials (RCT) are lacking. The aim of this RCT is to investigate whether beta-blocker therapy in patients with COPD without diagnosed cardiovascular disease is associated with a decreased 1-year risk of the composite endpoint of death, exacerbations, or cardiovascular events.Methods: The Beta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE) study is an open-label, multicentre, prospective RCT. A total of 1700 patients with COPD will be randomly assigned to either standard COPD care and metoprolol at a target dose of 100 mg per day or to standard COPD care only. The primary endpoint is a composite of death, COPD exacerbations, and cardiovascular events. Major exclusion criteria are ischemic heart disease, left-sided heart failure, cerebrovascular disease, critical limb ischemia, and atrial fibrillation/flutter. Study visits are an inclusion visit, a metoprolol titration visit at 1 month, follow-up by telephone at 6 months, and a final study visit after 1 year. Outcome data are obtained from medical history and record review during study visits, as well as from national registries.Discussion: BRONCHIOLE is a pragmatic randomized trial addressing the potential of beta-blockers in patients with COPD. The trial is expected to provide relevant clinical data on the efficacy of this treatment on patient-related outcomes in patients with COPD.
  •  
55.
  •  
56.
  • Wan, Y., et al. (författare)
  • First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo
  • 2004
  • Ingår i: J Med Chem. - : American Chemical Society (ACS). - 0022-2623 .- 1520-4804. ; 47:6, s. 1536-1546
  • Tidskriftsartikel (refereegranskat)abstract
    • In this investigation, it is demonstrated that the first nonpeptide AT(1) receptor agonist L-162,313 (1), disclosed in 1994, also acts as an agonist at the AT(2) receptor. In anesthetized rats, administration of compound 1 intravenously or locally in the duodenum increased duodenal mucosal alkaline secretion, effects that were sensitive to the selective AT(2) receptor antagonist PD-123,319. The data strongly suggest that 1 is an AT(2) receptor agonist in vivo. To the best of our knowledge, this substance is the first nonpeptidic low-molecular weight compound with an agonistic effect mediated through the AT(2) receptor.
  •  
57.
  • Wimo, Anders, et al. (författare)
  • The societal costs of dementia in Sweden 2012 : relevance and methodological challenges in valuing informal care
  • 2016
  • Ingår i: Alzheimer's Research & Therapy. - : Springer Science and Business Media LLC. - 1758-9193. ; 8
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: In this study, we sought to estimate the societal cost of illness in dementia in Sweden in 2012 using different costing approaches to highlight methodological issues.Methods: We conducted a prevalence-based cost-of-illness study with a societal perspective.Results: The societal costs of dementia in Sweden in 2012 were SEK 62.9 billion (approximately €7.2 billion, approximately US$ 9.0 billion) or SEK 398,000 per person with dementia (approximately €45,000, approximately US$ 57,000). By far the most important cost item is the cost of institutional care: about 60% of the costs. In the sensitivity analysis, different quantification and costing approaches for informal care resulted in a great variation in the total societal cost, ranging from SEK 60 billion (€6.8 billion, US$ 8.6 billion) to SEK 124 billion (€14.1 billion, US$ 17.8 billion).Conclusions: The societal costs of dementia are very high. The cost per person with dementia has decreased somewhat, mainly because of de-institutionalisation. The majority of the costs occur in the social care sector, but the costing of informal care is crucial for the cost estimates.
  •  
58.
  • Aad, G., et al. (författare)
  • 2013
  • Tidskriftsartikel (refereegranskat)
  •  
59.
  • Aad, G., et al. (författare)
  • 2011
  • Tidskriftsartikel (refereegranskat)
  •  
60.
  • Aad, G., et al. (författare)
  • 2013
  • Tidskriftsartikel (refereegranskat)
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 51-60 av 4186
Typ av publikation
tidskriftsartikel (2535)
konferensbidrag (785)
rapport (200)
bokkapitel (190)
doktorsavhandling (145)
annan publikation (111)
visa fler...
forskningsöversikt (33)
samlingsverk (redaktörskap) (28)
bok (27)
licentiatavhandling (27)
recension (21)
patent (4)
proceedings (redaktörskap) (3)
konstnärligt arbete (2)
visa färre...
Typ av innehåll
refereegranskat (3147)
övrigt vetenskapligt/konstnärligt (918)
populärvet., debatt m.m. (118)
Författare/redaktör
Aad, G (399)
Abbott, B. (399)
Adye, T. (397)
Aleksa, M. (397)
Abdinov, O (396)
Abramowicz, H. (396)
visa fler...
Abreu, H. (396)
Aielli, G. (396)
Akimov, A. V. (396)
Albrand, S. (396)
Alexander, G. (396)
Alhroob, M. (396)
Amako, K. (396)
Amelung, C. (396)
Amram, N. (396)
Anastopoulos, C. (396)
Anderson, K. J. (396)
Annovi, A. (396)
Antonelli, M. (396)
Arabidze, G. (396)
Arai, Y. (396)
Arnaez, O. (396)
Asai, S. (396)
Asquith, L. (396)
Assamagan, K. (396)
Bacci, C. (396)
Bachacou, H. (396)
Backes, M. (396)
Baker, O. K. (396)
Banas, E. (396)
Barisonzi, M. (396)
Barklow, T. (396)
Batley, J. R. (396)
Bauer, F. (396)
Beau, T. (396)
Beck, H. P. (396)
Bella, G. (396)
Bellomo, M. (396)
Beltramello, O. (396)
Benary, O. (396)
Benekos, N. (396)
Benhammou, Y. (396)
Beringer, J. (396)
Berry, T. (396)
Bilokon, H. (396)
Blumenschein, U. (396)
Boehler, M. (396)
Boisvert, V. (396)
Boonekamp, M. (396)
Borisov, A. (396)
visa färre...
Lärosäte
Lunds universitet (1300)
Uppsala universitet (982)
Umeå universitet (703)
Kungliga Tekniska Högskolan (616)
Göteborgs universitet (416)
Stockholms universitet (395)
visa fler...
Linköpings universitet (339)
Chalmers tekniska högskola (338)
Karolinska Institutet (338)
Mittuniversitetet (168)
Linnéuniversitetet (148)
Luleå tekniska universitet (101)
Jönköping University (100)
Örebro universitet (98)
Sveriges Lantbruksuniversitet (87)
RISE (81)
Handelshögskolan i Stockholm (65)
Mälardalens universitet (58)
Högskolan Dalarna (49)
Malmö universitet (40)
Högskolan i Skövde (30)
Högskolan i Gävle (28)
Högskolan i Borås (26)
VTI - Statens väg- och transportforskningsinstitut (26)
Högskolan Kristianstad (19)
Karlstads universitet (19)
Högskolan Väst (15)
Södertörns högskola (14)
Naturvårdsverket (13)
Högskolan i Halmstad (9)
Blekinge Tekniska Högskola (8)
IVL Svenska Miljöinstitutet (8)
Gymnastik- och idrottshögskolan (6)
Naturhistoriska riksmuseet (5)
Marie Cederschiöld högskola (5)
Försvarshögskolan (4)
Kungl. Konsthögskolan (4)
Riksantikvarieämbetet (3)
Sophiahemmet Högskola (2)
Havs- och vattenmyndigheten (2)
Röda Korsets Högskola (1)
Kungl. Musikhögskolan (1)
visa färre...
Språk
Engelska (3659)
Svenska (487)
Odefinierat språk (20)
Norska (7)
Latin (4)
Spanska (3)
visa fler...
Danska (2)
Kinesiska (2)
Ryska (1)
Nederländska (1)
visa färre...
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (1245)
Naturvetenskap (1056)
Teknik (930)
Samhällsvetenskap (450)
Humaniora (177)
Lantbruksvetenskap (82)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy