| 61. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Hälsopedagogik
- 2004
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Rapport (övrigt vetenskapligt/konstnärligt)
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| 62. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Influence on spontaneous tissue inflammation by the major histocompatibility complex region in the nonobese diabetic mouse.
- 2005
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Ingår i: Scandinavian Journal of Immunology. - : Wiley. - 1365-3083 .- 0300-9475. ; 61:2, s. 119-127
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Tidskriftsartikel (refereegranskat)abstract
- We investigated the role of the major histocompatibility complex (MHC) region in the specificity of autoimmunity by analysing specifically the development of sialadenitis, but also insulitis, nephritis and autoantibody production in autoimmune-prone nonobese diabetic (NOD) mice where the MHC H2g7 haplotype had been exchanged for the H2q (NOD.Q) or H2p (NOD.P) haplotype. The exchange of H2 haplotype did not affect the frequency of sialadenitis because the H2q and H2p congenic NOD strains developed sialadenitis with the same incidence as NOD. However, the severity of sialadenitis varied among the strains, as NOD.Q > NOD > NOD.P. At 11–13 weeks of age, the NOD.Q (H2q) female mice developed more severe sialadenitis compared to NOD.P (H2p) (P = 0.038). At 20 weeks, the NOD (H2g7) female mice showed more severe sialadenitis than NOD.P (P = 0.049). This is in contrast to the development of insulitis in the present strains, because the incidence of insulitis was almost completely inhibited by the replacement of the H2g7 haplotype of NOD. The incidence of insulitis in NOD.Q was 11–22%, compared to 75% in NOD, which correlated well with lower titres of anti-glutamic acid decarboxylase (anti-GAD) antibodies in NOD.Q compared to NOD (P = 0.009). However, the introduction of the H2q haplotype into the NOD strain instead directed the autoimmune response towards the production of lupus types of autoantibodies, because the incidence of antinuclear antibodies (ANA) in NOD.Q was 89% compared with 11% in NOD.P and 12% in NOD mice, which in turn correlated with a high incidence of nephritis in NOD.Q compared to NOD. Consequently, we show that different haplotypes of MHC are instrumental in directing the specificity of the spontaneous autoimmune inflammation. This article is cited by:
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| 63. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Mouse models for rheumatoid arthritis
- 2002
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Ingår i: Trends in Genetics. - 1362-4555. ; 18:6, s. 7-13
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Tidskriftsartikel (refereegranskat)abstract
- Rheumatoid arthritis (RA) affects millions of people world wide causing considerable human suffering and large socioeconomic costs. Increased knowledge of pathological pathways involved in RA will enable development of modern drugs, with reduced side effects. The mouse models offer an attractive approach to dissect the genetic and molecular mechanisms of RA.
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| 64. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Moving From Idea to Action : Promoting Physical Activity by Empowering Adolescents
- 2014
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Ingår i: Health Promotion Practice. - : SAGE Publications. - 1524-8399 .- 1552-6372. ; 15:6, s. 812-818
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Tidskriftsartikel (refereegranskat)abstract
- Background. Physical activity provides fundamental health benefits for children and youth. The aim of the study was to explore the possibility of conducting an empowerment-inspired intervention and examine the impact of the intervention in promoting moderate and vigorous physical activity (MVPA) among adolescents. Method. A nonrandomized trial with a concurrent control group was carried out. Physical activity data were collected before and after the intervention with daily questions by short message service. Self-efficacy, social support, and attitude were also measured before and after the intervention since they were possible mediators. Results. The intervention was created by the students, the researchers, and the teachers using an empowerment-based approach. Students in the intervention group (n = 21) increased their MVPA on average by 4.9 (SD = 28.9) minutes per day, and students in the control group (n = 25) reduced their MVPA on average by 25.4 (SD = 23.0) minutes per day (p = .000). Conclusions. The intervention might have contributed to a promotion of physical activity among students in the intervention group. The most valuable contribution this study provides is the knowledge that it is possible to develop and conduct an empowerment-inspired intervention to promote adolescent physical activity.
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| 65. |
- Lindqvist, Anna-Karin, et al.
(författare)
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One Step Forward : Development of a Program Promoting Active School Transportation
- 2018
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Ingår i: JMIR Research Protocols. - : JMIR Publications. - 1929-0748. ; 7:5
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Physical activity promotes health and learning. However, up to 80% of the children in industrialized countries do not achieve the recommended level of daily physical activity. By encouraging children to use active school transportation (AST), it is possible to increase their overall physical activity.OBJECTIVE: The aim of this paper was to present the development of an AST intervention using Intervention Mapping (IM) to promote children's physical activity.METHODS: The principles of IM were applied to guide the development of the intervention. The process was divided into 3 phases. First, a literature review and collection of experiences of stakeholders were carried out to gain a broad perspective on the problem and possible solutions. Thereafter, an analysis of the critical environmental and behavioral factors affecting outcome was conducted, which guided the choice of tangible components of the intervention. Finally, a plan of evaluation and implementation was established.RESULTS: A structured program to increase AST among children was developed, consisting of 3 subsequent phases that are described in detail. Implementation took place, and evaluation of the intervention is being carried out.CONCLUSIONS: IM proved to be a valuable method to develop a structured AST intervention for children. By following the steps of the IM process, it became evident that empowerment and gamification are 2 promising avenues to consider when designing AST interventions in a school context. By engaging end users and including important agents, such as parents and teachers, who control the environmental factors, the possibility to design a sustainable program increases. In addition, gamification made it possible to integrate learning into AST, which could motivate schools to devote time and effort to implementing this program.
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| 66. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Parent participation plays an important part in promoting physical activity
- 2015
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Ingår i: International Journal of Qualitative Studies on Health and Well-being. - : Informa UK Limited. - 1748-2623 .- 1748-2631. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- Although physical activity (PA) is an important and modifiable determinant of health, in Sweden only 15% of boys and 10%of girls aged 15 years old achieve the recommended levels of PA 7 days per week. Adolescents’ PA levels are associated withsocial influence exerted by parents, friends, and teachers. The purpose of this study was to describe parents’ experiencesof being a part of their adolescents’ empowerment-inspired PA intervention. A qualitative interview study was performedat a school in the northern part of Sweden. A total of 10 parents were interviewed, and the collected data were analyzedwith qualitative content analysis. Three subthemes were combined into one main theme, demonstrating that parents are oneimportant part of a successful PA intervention. The life of an adolescent has many options and demands that make it difficultto prioritize PA. Although parents felt that they were important in supporting their adolescent, a successful PA interventionmust have multiple components. Moreover, the parents noted that the intervention had a positive effect upon not only theiradolescents’, but also their own PA. Interventions aimed at promoting PA among adolescents should include measures tostimulate parent participation, have an empowerment approach, and preferably be school-based.
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| 67. |
- Lindqvist, Anna-Karin, et al.
(författare)
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Peers, parents and phones : Swedish adolescents and health promotion
- 2012
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Ingår i: International Journal of Qualitative Studies on Health and Well-being. - : Informa UK Limited. - 1748-2623 .- 1748-2631. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- Many unhealthy behaviors are created during adolescence and follow the individual into adulthood. In addition, health behaviors often occur in clusters as those who are inactive are more likely to eat unhealthy food and smoke. This makes the early foundation of healthy behaviors vital. The aim was to describe and develop an understanding of adolescents' awareness and experiences concerning health promotion. Data was collected using focus groups with a total of 28 seventh graders and was analysed with latent qualitative content analysis. One main theme was identified; being competent, ambivalent and creative at the same time. The following three subthemes also emerged: being a digital native for better and for worse, knowing what is healthy, and sometimes doing it, and considering change and having ideas of how change could be supported. The main theme elucidates how the majority of students were informed and able but they did not always prioritize their health. The concept of health promotion relies upon the engagement of the individual; however, although the students had clear ideas about how they would like to change their own behaviors, they felt a need for support. Interestingly, the students were able to make several suggestions about the kind of support that would make a difference to their adoption to more healthy modes of living. They suggested information and communication technology (ICT), for example encouraging text messages (SMS), and social support, for example parents setting rules and peers inspiring them to adhere to a healthy behavior. The knowledge gained from this study echoes our view of inclusion and this could be helpful for those who encounter the challenge of promoting health among adolescents
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| 68. |
- Lindqvist, Anna-Karin
(författare)
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Physiotherapists enabling school children's physical activity using social cognitive theory, empowerment and technology
- 2017
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Ingår i: European Journal of Physiotherapy. - : Taylor & Francis. - 2167-9169 .- 2167-9177. ; 19:3, s. 147-153
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To contribute knowledge concerning how physiotherapists using social cognitive theory, empowerment and information and communication technology can promote children’s physical activity in a school context.Methodology: Four studies were conducted in the northern part of Sweden and a qualitative discourse analysis of the results from all four studies was performed to enable a more comprehensive understanding. Three of the studies involved children, and one study involved parents.Major findings: The findings formed three themes: A, Acknowledging empowerment; B, Bonded forces overcame barriers; and C, Competence and motivation enable change. The first theme includes the act of creating the intervention using an empowerment approach. The second theme concerns barriers to being physically active and social support from parents and peers regarding physical activity promotion. The third theme concerns motivation and associated personal factors, such as self-efficacy.Principal conclusion: This course of action might be a way for physiotherapists to promote children’s physical activity using social cognitive theory, empowerment and information and communication technology in a school context. An empowerment approach that includes the formation of partnerships with children is a promising avenue for developing physical activity interventions in schools. In addition, physical activity interventions should attempt to build on children’s self-efficacy and make physical activity opportunities fun and enjoyable.
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| 69. |
- Lindqvist, Anna-Karin
(författare)
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Promoting adolescents' physical activity @ school
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall aim of this thesis was to explore the development of a health-promoting intervention that uses empowerment and information and communication technology, to examine the impact of the intervention and to describe adolescents' and parents' experiences of the intervention. This thesis includes four studies, three of which used a qualitative approach (I, III and IV) and one of which used a mixed method approach (II). Three of the studies involved adolescents (I-III), and one study involved parents (IV).Data were generated using focus groups and analyzed using latent content analysis (study I). Physical activity, self-efficacy, social support, and attitude data were collected before and after the intervention and analyzed using descriptive and analytical statistics (study II). Adolescents were interviewed and the data were analyzed using latent content analysis (study III). The parents were interviewed and the data were analyzed using latent content analysis (study IV). The findings formed three themes: A, Acknowledging empowerment andphysical activity; B, Bonded forces overcame barriers; and C, Competence andmotivation enable change. The first theme concerns behavior regarding health promotion, specifically physical activity. That theme includes the act of creating the intervention using an empowerment approach and the physical activity behavior after the intervention. The second theme concerns barriers to being physically active and social support from parents and peers regarding physical activity promotion. The third theme concerns motivation and associated personal factors, such as knowledge and self-efficacy.The main conclusion of this thesis is that it is possible to develop anempowerment-inspired health-promoting intervention with a positive impact.Furthermore, interventions that aim to promote physical activity among adolescents should preferably include information and communication technology from the adolescents’ reality, involve actions that stimulate the participation of both parents and peers and be school-based.
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| 70. |
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