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Numrering	Referens	Omslagsbild	Hitta
11.	den Hoed, Marcel, et al. (författare) Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders 2013 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:6, s. 621- Tidskriftsartikel (refereegranskat)
12.	Dupuis, J, et al. (författare) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk 2010 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 42:2, s. 105-U32 Tidskriftsartikel (refereegranskat)
13.	Ehret, GB, et al. (författare) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk 2011 Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 478:7367, s. 103-109 Tidskriftsartikel (refereegranskat)
14.	Ehret, GB, et al. (författare) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals 2016 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 48:10, s. 1171-1184 Tidskriftsartikel (refereegranskat)
15.	Evangelou, E, et al. (författare) Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits 2018 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 50:12, s. 1755-1755 Tidskriftsartikel (refereegranskat)
16.	Feng, Q, et al. (författare) Causal associations between urinary sodium with body mass, shape and composition: a Mendelian randomization study 2020 Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1, s. 17475- Tidskriftsartikel (refereegranskat)abstract Observational studies have found associations between urinary sodium (UNa) with obesity, body shape and composition; but the findings may be biased by residual confounding. The objective of this two-sample Mendelian randomization (MR) study was to analyze their causal associations in both sex-combined and sex-specific models. Genome-wide association studies of UNa, body mass index (BMI), BMI-adjusted waist-to-hip ratio (WHR), body fat (BF) percentage and estimated glomerular filtration rate (eGFR) were identified. We initially extracted fifty SNPs associated with UNa at significance level of 5 × 10–8, but further removed those SNPs with potential horizontal pleiotropy. Univariable and multivariable MR with adjustment for eGFR were performed. Inverse-variance weighted MR was performed as the primary analysis, with MR-Egger methods as sensitivity analysis. The potential bidirectional association between BMI and UNa was investigated. All exposure and outcomes were continuous, and the effect measure was regression coefficients (beta) and their 95% confidence intervals (95% CI). The total sample size was up to 322 154. UNa was causally associated with increased BMI in both men [eGFR-adjusted beta 0.443 (0.163–0.724)] and women [0.594 (0.333–0.855)]. UNa caused BF percentage increase in men [0.622 (0.268–0.976)] and women [0.334 (0.007–0.662)]. UNa significantly elevated BMI-adjusted WHR in men [0.321 (0.094–0.548)], but not in women [0.170 (− 0.052 to 0.391)]. Additionally, we found that BMI causally increased UNa [0.043 (0.023–0.063)]. UNa increased BMI and BF percentage. Salt intake affects male body shape by increasing BMI-adjusted WHR, but showed no effects on female body shape. The bidirectional association between BMI and UNa suggested that salt reduction measures and weight reduction measures should be implemented simultaneously to break the vicious cycle and gain more health benefits.
17.	Franks, PW, et al. (författare) Gene expression and genetic association studies suggest a role for the Parkinson's gene PINK1 in the pathogenesis of type 2 diabetes 2007 Ingår i: DIABETOLOGIA. - 0012-186X. ; 50, s. S134-S134 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
18.	Giannakopoulou, O, et al. (författare) The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study 2021 Ingår i: JAMA psychiatry. - : American Medical Association (AMA). - 2168-6238 .- 2168-622X. ; 78:11, s. 1258-1269 Tidskriftsartikel (refereegranskat)
19.	Gorski, M, et al. (författare) Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies 2022 Ingår i: Kidney international. - : Nature Publishing Group. - 1523-1755 .- 0085-2538. ; 102:3, s. 624-639 Tidskriftsartikel (refereegranskat)
20.	Graff, M, et al. (författare) Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults 2017 Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 13:8, s. e1006972- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)

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Resultat 11-20 av 71

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Typ av publikation: tidskriftsartikel (68); konferensbidrag (2)

Typ av innehåll: refereegranskat (62); övrigt vetenskapligt/konstnärligt (8)

Författare/redaktör: Loos, RJF (71); Wareham, NJ (34); Metspalu, A (29); Hayward, C. (29); Esko, T (28); Boehnke, M (28); visa fler...; Boerwinkle, E (26); Gieger, C (26); Boomsma, DI (25); van Duijn, CM (25); Gudnason, V (25); Uitterlinden, AG (25); Lehtimaki, T. (25); Snieder, H. (25); Laakso, M. (25); Salomaa, V (25); Zhao, JH (25); Chambers, JC (25); Wilson, JF (24); Chasman, DI (24); Ridker, PM (24); Peters, A (23); Langenberg, C. (23); Pedersen, NL (23); Smith, AV (23); Psaty, BM (23); Jackson, AU (23); Lind, L (23); Willemsen, G (22); Rotter, JI (22); van der Harst, P (22); Rudan, I. (22); Magi, R (22); Magnusson, PKE (21); Hofman, A (21); Nolte, IM (21); Vollenweider, P. (21); Campbell, H (21); Kuusisto, J. (21); Mohlke, KL (21); Goel, A. (21); Watkins, H (21); Polašek, O. (21); Harris, TB (21); Kooner, JS (21); Mahajan, A. (20); Teumer, A (20); Tuomilehto, J. (20); Stefansson, K (20); Vitart, V (20); visa färre...

Lärosäte: Karolinska Institutet (70); Uppsala universitet (27); Lunds universitet (24); Umeå universitet (13); Göteborgs universitet (10); Örebro universitet (5); visa fler...; Högskolan Dalarna (4); Stockholms universitet (1); Jönköping University (1); Handelshögskolan i Stockholm (1); Högskolan i Skövde (1); visa färre...

Språk: Engelska (71)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (35); Naturvetenskap (6); Samhällsvetenskap (2)

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