SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Olsson T) "

Sökning: WFRF:(Olsson T)

  • Resultat 2101-2110 av 2118
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
2101.
  •  
2102.
  • Zhang, Tongwu, et al. (författare)
  • Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes
  • 2018
  • Ingår i: Genome Research. - : Cold Spring Harbor Laboratory. - 1088-9051 .- 1549-5469. ; 28:11, s. 1621-1635
  • Tidskriftsartikel (refereegranskat)abstract
    • Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type-specific regulatory landscape of human melanocytes, which give rise to melanoma but account for <5% of typical human skin biopsies, we performed an eQTL analysis in primary melanocyte cultures from 106 newborn males. We identified 597,335 cis-eQTL SNPs prior to linkage disequilibrium (LD) pruning and 4997 eGenes (FDR < 0.05). Melanocyte eQTLs differed considerably from those identified in the 44 GTEx tissue types, including skin. Over a third of melanocyte eGenes, including key genes in melanin synthesis pathways, were unique to melanocytes compared to those of GTEx skin tissues or TCGA melanomas. The melanocyte data set also identified trans-eQTLs, including those connecting a pigmentation-associated functional SNP with four genes, likely through cis-regulation of IRF4. Melanocyte eQTLs are enriched in cis-regulatory signatures found in melanocytes as well as in melanoma-associated variants identified through genome-wide association studies. Melanocyte eQTLs also colocalized with melanoma GWAS variants in five known loci. Finally, a transcriptome-wide association study using melanocyte eQTLs uncovered four novel susceptibility loci, where imputed expression levels of five genes (ZFP90, HEBP1, MSC, CBWD1, and RP11-383H13.1) were associated with melanoma at genome-wide significant P-values. Our data highlight the utility of lineage-specific eQTL resources for annotating GWAS findings, and present a robust database for genomic research of melanoma risk and melanocyte biology.
  •  
2103.
  • Zhao, M., et al. (författare)
  • A near-complete and time-calibrated phylogeny of the Old World flycatchers, robins and chats (Aves, Muscicapidae)
  • 2023
  • Ingår i: Molecular Phylogenetics and Evolution. - : Elsevier BV. - 1055-7903 .- 1095-9513. ; 178
  • Tidskriftsartikel (refereegranskat)abstract
    • The Old World flycatchers, robins and chats (Aves, Muscicapidae) are a diverse songbird family with over three hundred species. Despite continuous efforts over the past two decades, there is still no comprehensive and wellresolved species-level phylogeny for Muscicapidae. Here we present a supermatrix phylogeny that includes all 50 currently recognized genera and ca. 92% of all the species, built using data from up to 15 mitochondrial and 13 nuclear loci. In addition to assembling nucleotide sequences available in public databases, we also extracted sequences from the genome assemblies and raw sequencing reads from GenBank and included a few unpublished sequences. Our analyses resolved the phylogenetic position for several previously unsampled taxa, for example, the Grand Comoro Flycatcher Humblotia flavirostris, the Collared Palm Thrush Cichladusa arquata, and the Taiwan Whistling-Thrush Myophonus insularis, etc. We also provide taxonomic recommendations for genera that exhibit paraphyly or polyphyly. Our results suggest that Muscicapidae diverged from Turdidae (thrushes and allies) in the early Miocene, and the most recent common ancestors for the four subfamilies (Muscicapinae, Niltavinae, Cossyphinae and Saxicolinae) all arose around the middle Miocene.
  •  
2104.
  •  
2105.
  •  
2106.
  •  
2107.
  •  
2108.
  •  
2109.
  •  
2110.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 2101-2110 av 2118
Typ av publikation
tidskriftsartikel (1586)
konferensbidrag (469)
bokkapitel (18)
forskningsöversikt (15)
annan publikation (13)
rapport (11)
visa fler...
doktorsavhandling (3)
bok (1)
licentiatavhandling (1)
visa färre...
Typ av innehåll
refereegranskat (1566)
övrigt vetenskapligt/konstnärligt (543)
populärvet., debatt m.m. (8)
Författare/redaktör
Olsson, T (858)
Hillert, J (274)
Zhang, Z. (116)
Meyer, J. (108)
Schmitt, S. (107)
Rizvi, E. (106)
visa fler...
South, D. (106)
Diaconu, C. (106)
Ferencei, J. (106)
Greenshaw, T. (106)
Lebedev, A. (106)
Levonian, S. (106)
Andreev, V. (106)
Belousov, A. (106)
Boudry, V. (106)
Brisson, V. (106)
Cvach, J. (106)
Dodonov, V. (106)
Eckerlin, G. (106)
Egli, S. (106)
Favart, L. (106)
Fedotov, A. (106)
Gabathuler, E. (106)
Ghazaryan, S. (106)
Goerlich, L. (106)
Gogitidze, N. (106)
Grab, C. (106)
Horisberger, R. (106)
Kapichine, M. (106)
Kiesling, C. (106)
Lubimov, V. (106)
Malinovski, E. (106)
Meyer, H. (106)
Niebuhr, C. (106)
Nowak, G. (106)
Pascaud, C. (106)
Perez, E. (106)
Pitzl, D. (106)
Roosen, R. (106)
Rostovtsev, A. (106)
Soloviev, Y. (106)
Spaskov, V. (106)
Specka, A. (106)
Stella, B. (106)
Straumann, U. (106)
Traynor, D. (106)
Turnau, J. (106)
Vallee, C. (106)
Vazdik, Y. (106)
Zalesak, J. (106)
visa färre...
Lärosäte
Karolinska Institutet (1208)
Lunds universitet (377)
Uppsala universitet (319)
Göteborgs universitet (190)
Kungliga Tekniska Högskolan (138)
Umeå universitet (99)
visa fler...
Linköpings universitet (86)
Chalmers tekniska högskola (75)
Örebro universitet (65)
Stockholms universitet (40)
Sveriges Lantbruksuniversitet (29)
RISE (26)
Malmö universitet (24)
Karlstads universitet (22)
Mittuniversitetet (17)
Jönköping University (13)
Linnéuniversitetet (13)
Luleå tekniska universitet (9)
Högskolan i Gävle (6)
Södertörns högskola (5)
Mälardalens universitet (4)
Blekinge Tekniska Högskola (4)
Högskolan i Borås (3)
Högskolan Dalarna (3)
Högskolan Kristianstad (2)
Handelshögskolan i Stockholm (2)
Högskolan i Skövde (2)
Gymnastik- och idrottshögskolan (2)
Naturhistoriska riksmuseet (2)
Högskolan i Halmstad (1)
Högskolan Väst (1)
Marie Cederschiöld högskola (1)
VTI - Statens väg- och transportforskningsinstitut (1)
IVL Svenska Miljöinstitutet (1)
visa färre...
Språk
Engelska (2098)
Svenska (18)
Odefinierat språk (2)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (519)
Naturvetenskap (392)
Teknik (136)
Samhällsvetenskap (46)
Lantbruksvetenskap (17)
Humaniora (5)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy