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Sökning: WFRF:(Poludniowski G)

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11.
  • Karambatsakidou, A, et al. (författare)
  • Age-specific and gender-specific radiation risks in paediatric angiography and interventional cardiology: conversion coefficients and risk reference values
  • 2020
  • Ingår i: The British journal of radiology. - : British Institute of Radiology. - 1748-880X .- 0007-1285. ; 93:1110, s. 20190869-
  • Tidskriftsartikel (refereegranskat)abstract
    • To estimate risk for exposure-induced cancer death (REID), organ-specific risks of exposure-induced cancer death (REIDHT) and associated conversion coefficients (CCREID:KAP=REID/kerma-area product (KAP), CCREIDHT:KAP=REIDHT/KAP) in paediatric cardiac catheterizations using data from radiation dose structured reports (RDSR). A novel risk surveillance tool consisting of age-specific and gender-specific risk reference values (RRVs) related to population cancer risk is suggested. Methods: The PCXMC v.2.0 code is used together with exposure-related information from RDSR from a cohort of 238 children to assess cancer risks and related conversion coefficients. The KAP corresponding to 1 in 1000 of increased REID is used to define age-specific and gender-specific KAP values to monitor risk in such patient cohorts, here denoted as RRVs. Results: The REID estimates ranged from below 1 up to 300 in 100,000, and the RRVs for the different age groups and gender ranged from 0.77 Gycm2 and 2.1 Gycm2 for neonates (female, male) to 11 Gycm2 and 25 Gycm2 for 15-year-olds (female, male). The CCREID:KAP and CCREIDHT:KAP decreased biexponentially with increased age, being notably higher for female patients. Conclusions: Prominent risk contributing organs were the lungs and the (female) breast. The concept of age-specific and gender-specific RRVs related to population cancer risk is introduced and is intended to be used as a supporting tool for physicians performing such interventions. Advances in knowledge: Age-related and gender-related conversion coefficients for radiation risk, CCREID:KAP and CCREIDHT:KAP, are introduced and a novel risk surveillance concept, the RRV, is suggested for paediatric cardiac catheterizations.
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  • Merzan, D., et al. (författare)
  • Evaluating the impact of scan settings on automatic tube current modulation in CT using a novel phantom
  • 2017
  • Ingår i: British Journal of Radiology. - : British Institute of Radiology. - 0007-1285 .- 1748-880X. ; 90:1069
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The aim of this study was to make a comprehensive evaluation of how variable scan settings can affect the performance of automatic tube current modulation (ATCM) in recent CT scanners from the four major manufacturers. Methods: A phantom was designed and manufactured for the purpose of evaluating ATCM. The phantom was scanned with four categories of systematically varied settings (scan projection radiograph, technique and reconstruction parameters and phantom miscentring). The performance of ATCM, in terms of applied tube current and noise uniformity, for the scans with varied settings was compared with a reference scan using subjective and quantitative approaches. Results: The ATCM implemented by each manufacturer is based on different principles and any affect to the performance of the ATCM, when varying scan settings, will manifest differently among the vendors. The results are summarized in four tables corresponding to the categories of varied settings. Conclusion: The developed phantom proved useful for evaluating the ATCM. It is important to understand how different implementations (vendor specific) of ATCM perform in order to make informed decisions about the selection of scan settings when designing protocols. The resulting tables can serve as a reference for understanding the different implementations of ATCM and highlight settings that should be taken into consideration when adjusting an imaging protocol. Advances in knowledge: The results from this work can serve as a reference for how changes in geometry or scan settings can affect the performance of ATCM, in terms of tube current and noise. 
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  • Nowik, P., et al. (författare)
  • The synthetic localizer radiograph – A new CT scan planning method
  • 2019
  • Ingår i: Physica medica (Testo stampato). - : Elsevier BV. - 1120-1797 .- 1724-191X. ; 61, s. 58-63
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To investigate if the conventional localizer radiograph (LR)can be replaced by a synthetic LR (SLR), generated from a low-dose spiral CT scan, for CT scan planning with minimal changes to current clinical workflows. Methods: A dosimetric comparison of SLRs and LRs was made using Monte Carlo methods. Water equivalent diameters (WEDs)of a centered and mis-centered phantom were estimated from low-dose spiral CT scans and LRs acquired at different angles. Body sizes, in the form of two lengths and two diameters obtained from SLRs and LRs, were compared for 10 patients (4 men and 6 women with a mean age of 74.8 and 76.2 years respectively)undergoing CT of thorax and abdomen. The image quality of SLRs for CT scan planning relative to LRs was rated using a 5-grade scale by four radiologists and two CT radiographers. Results: An SLR can be obtained at a comparable effective dose to that of traditionally acquired LRs: 0.14 mSv. WEDs from LRs were more affected by mis-centering than WEDs calculated from low-dose spiral scans. One significant discrepancy of estimated body sizes was observed, the broadest part of the patient that on lateral localizers showed a mean deviation of 17.7 mm (range: 7.3–28.7 mm, p < 0.001). The anteroposterior/posteroanterior SLR image quality was assessed as better compared to an LR while the same could not be shown for lateral localizers. Conclusions: SLRs based on low-dose spiral scans can replace LRs for CT planning.
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  • Resultat 11-20 av 37

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