↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Severi G) "

Search: WFRF:(Severi G)

Result 11-20 of 178

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
11.	Weinmayr, G, et al. (author) Long-term exposure to several constituents and sources of PM2.5 is associated with incidence of upper aerodigestive tract cancers but not gastric cancer: Results from the large pooled European cohort of the ELAPSE project 2024 In: The Science of the total environment. - 1879-1026. ; 912, s. 168789- Journal article (peer-reviewed)
12.	Agarwal, D, et al. (author) FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium 2014 In: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 110:4, s. 1088-1100 Journal article (peer-reviewed)
13.	Ahmed, S, et al. (author) Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2 2009 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 41:5, s. 585-590 Journal article (peer-reviewed)
14.	Alpar, A, et al. (author) Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress 2018 In: The EMBO journal. - : EMBO. - 1460-2075 .- 0261-4189. ; 37:21 Journal article (peer-reviewed)
15.	Andersen, ZJ, et al. (author) Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study 2022 In: Environment international. - 1873-6750. ; 170, s. 107581- Journal article (peer-reviewed)
16.	Andersen, ZJ, et al. (author) Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study 2022 In: Environment international. - : Elsevier BV. - 1873-6750 .- 0160-4120. ; 170, s. 107581- Journal article (peer-reviewed)
17.	Bereziartua, A, et al. (author) Exposure to surrounding greenness and natural-cause and cause-specific mortality in the ELAPSE pooled cohort 2022 In: Environment international. - : Elsevier BV. - 1873-6750 .- 0160-4120. ; 166, s. 107341- Journal article (peer-reviewed)
18.	Chen, J, et al. (author) Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project 2022 In: British journal of cancer. - 1532-1827. Journal article (peer-reviewed)
19.	Duell, EJ, et al. (author) Plasma microRNAs as biomarkers of pancreatic cancer risk in a prospective cohort study 2017 In: International journal of cancer. - : Wiley. - 1097-0215 .- 0020-7136. ; 141:5, s. 905-915 Journal article (peer-reviewed)
20.	Garcia-Closas, Montserrat, et al. (author) Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics 2008 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 4:4, s. e1000054- Journal article (peer-reviewed)abstract A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9), mitogen-activated protein kinase 3 K1 (MAP3K1), 8q24, and lymphocyte-specific protein 1 (LSP1)) associated with breast cancer risk. We investigated whether the associations between these SNPs and breast cancer risk varied by clinically important tumor characteristics in up to 23,039 invasive breast cancer cases and 26,273 controls from 20 studies. We also evaluated their influence on overall survival in 13,527 cases from 13 studies. All participants were of European or Asian origin. rs2981582 in FGFR2 was more strongly related to ER-positive (per-allele OR (95%CI) = 1.31 (1.27-1.36)) than ER-negative (1.08 (1.03-1.14)) disease (P for heterogeneity = 10(-13)). This SNP was also more strongly related to PR-positive, low grade and node positive tumors (P = 10(-5), 10(-8), 0.013, respectively). The association for rs13281615 in 8q24 was stronger for ER-positive, PR-positive, and low grade tumors (P = 0.001, 0.011 and 10(-4), respectively). The differences in the associations between SNPs in FGFR2 and 8q24 and risk by ER and grade remained significant after permutation adjustment for multiple comparisons and after adjustment for other tumor characteristics. Three SNPs (rs2981582, rs3803662, and rs889312) showed weak but significant associations with ER-negative disease, the strongest association being for rs3803662 in TNRC9 (1.14 (1.09-1.21)). rs13281615 in 8q24 was associated with an improvement in survival after diagnosis (per-allele HR = 0.90 (0.83-0.97). The association was attenuated and non-significant after adjusting for known prognostic factors. Our findings show that common genetic variants influence the pathological subtype of breast cancer and provide further support for the hypothesis that ER-positive and ER-negative disease are biologically distinct. Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment.

Skapa referenser, mejla, bekava och länka

Permalink

Result 11-20 of 178

Refine your search

Type of publication: journal article (170); conference paper (7); research review (1)

Type of content: peer-reviewed (168); other academic/artistic (10)

Author/Editor: Severi, G (84); Severi, Gianluca (79); Giles, Graham G (57); Giles, GG (44); Easton, DF (41); Baglietto, L (40); show more...; Southey, MC (39); Hall, P (37); Chang-Claude, J (37); Albanes, Demetrius (36); Hopper, JL (36); Fasching, PA (35); Beckmann, MW (35); Garcia-Closas, M (33); Ekici, AB (32); Cox, A (32); Couch, FJ (32); Lissowska, J (32); Chenevix-Trench, G (32); Milne, RL (31); Nordestgaard, BG (31); Nevanlinna, H (31); Dunning, AM (30); Mannermaa, A (30); Kosma, VM (30); Czene, K (29); Anton-Culver, H (29); Chanock, Stephen J (29); Bojesen, SE (29); Kataja, V (29); Brauch, H (28); Pharoah, PDP (28); Johansson, Mattias (28); Benitez, J. (27); Riboli, Elio (27); Dork, T (27); Kraft, Peter (27); Le Marchand, Loïc (27); Lindblom, A (26); Schmidt, MK (26); Peto, J (26); Lambrechts, D (26); Margolin, S (25); Flesch-Janys, D (25); Chanock, SJ (25); Brenner, H (24); Blomqvist, C (24); Weiderpass, Elisabet ... (24); Zheng, Wei (24); Ziogas, A (24); show less...

University: Karolinska Institutet (128); Umeå University (77); Lund University (33); Uppsala University (27); University of Gothenburg (3); Stockholm University (3); show more...; Kristianstad University College (1); Linköping University (1); Stockholm School of Economics (1); Chalmers University of Technology (1); show less...

Language: English (177); Undefined language (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (89); Natural sciences (2); Engineering and Technology (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view