| 31. |
- Faryna, Khrystyna, et al.
(författare)
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Towards embedding stain-invariance in convolutional neural networks for H&E-stained histopathology
- 2024
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Ingår i: DIGITAL AND COMPUTATIONAL PATHOLOGY, MEDICAL IMAGING 2024. - : SPIE-INT SOC OPTICAL ENGINEERING. - 9781510671713 - 9781510671706
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Konferensbidrag (refereegranskat)abstract
- Convolutional neural networks (CNNs) are known to fail if a difference exists in the data they are trained and tested on, known as domain shifts. This sensitivity is particularly problematic in computational pathology, where various factors, such as different staining protocols and stain providers, introduce domain shifts. Many solutions have been proposed in the literature to address this issue, with data augmentation being one of the most popular approaches. While data augmentation can significantly enhance the performance of a CNN in the presence of domain shifts, it does not guarantee robustness. Therefore, it would be advantageous to integrate generalization to specific sources of domain shift directly into the network's capabilities when known to be present in the real world. In this study, we draw inspiration from roto-translation equivariant CNNs and propose a customized layer to enhance domain generalization and the CNN's ability to handle variations in staining. To evaluate our approach, we conduct experiments on two publicly available, multi-institutional datasets: CAMELYON17 and MIDOG.
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| 32. |
- Fernández-Ochoa, Álvaro, et al.
(författare)
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A case report of switching from specific vendor-based to R-based pipelines for untargeted LC-MS metabolomics
- 2020
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Ingår i: Metabolites. - : MDPI AG. - 2218-1989 .- 2218-1989. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- Data pre-processing of the LC-MS data is a critical step in untargeted metabolomics studies in order to achieve correct biological interpretations. Several tools have been developed for pre-processing, and these can be classified into either commercial or open source software. This case report aims to compare two specific methodologies, Agilent Profinder vs. R pipeline, for a metabolomic study with a large number of samples. Specifically, 369 plasma samples were analyzed by HPLC-ESI-QTOF-MS. The collected data were pre-processed by both methodologies and later evaluated by several parameters (number of peaks, degree of missingness, quality of the peaks, degree of misalignments, and robustness in multivariate models). The vendor software was characterized by ease of use, friendly interface and good quality of the graphs. The open source methodology could more effectively correct the drifts due to between and within batch effects. In addition, the evaluated statistical methods achieved better classification results with higher parsimony for the open source methodology, indicating higher data quality. Although both methodologies have strengths and weaknesses, the open source methodology seems to be more appropriate for studies with a large number of samples mainly due to its higher capacity and versatility that allows combining different packages, functions, and methods in a single environment.
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| 33. |
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| 34. |
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| 35. |
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| 36. |
- Hambsch, F. -J, et al.
(författare)
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Investigation of the Fission Process at IRMM
- 2011
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Ingår i: Journal of the Korean Physical Society. - : Korean Physical Society. - 0374-4884 .- 1976-8524. ; 59:2, s. 1654-1659
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Tidskriftsartikel (refereegranskat)abstract
- The investigation of the fission process is and has been a major undertaking at IRMM. The most recent investigations concerned the reaction (234)U(n,f) and (238)U(n,f) around vibrational resonances at the barrier of the fission cross-section. Furthermore prompt neutron emission of (252)Cf(SF) has been investigated understanding for the first time the prompt neutron multiplicity as a function of total kinetic energy (TKE). Theoretical modelling of reaction cross sections as well as prompt neutron multiplicity and spectra has been performed using the experimental data as input parameters. Also instrument developments for correlation measurements of fission fragment properties has been pursued in recent years with the time-of-flight spectrometer VERDI and detectors for prompt fission gamma-ray.
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| 37. |
- Huvila, Isto, 1976-
(författare)
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Social aspects of the ecology of information work
- 2011
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Ingår i: Information ecology and libraries. - Bratislava : Comenius University of Bratislava. ; , s. 27-36
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The model of the ecology of information work (Huvila, 2006, 2009) describes the relation of knowledge organisation systems, or in broader sense, the relation of information infrastructures and human information work. The present paper discusses the social aspects of information work and their impact on the interplay of information infrastructures and hu- man activity. The theoretical underpinnings of the discussion build on the ecological approach of Gibson, infrastructural theory and social informa- tion theory. The concluding remarks summarise a reading of the earlier model that places a specific emphasis on foregrounding the social pro- cesses relating to the emergence of information infrastructures and their related information work patterns.
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| 38. |
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| 39. |
- Jayamani, Jayaraj, et al.
(författare)
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Globulization mechanism of the primary Al of Al−15Cu alloy during slurry preparation for rheoforming
- 2005
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Ingår i: Metals and Materials International. - 1598-9623 .- 2005-4149. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- Semisolid slurries of Al-15Cu alloy were produced for rheoforming by a low temperature pouring technique. To investigate the morphological change of the slurry in terms of the particle mean diameter and the roundness factor, samples were extracted during the continuous cooling and the isothermal holding stage of the slurry by a simple technique of interrupt quenching. Results demonstrated that the fine-grained equiaxed dendritic structure, which formed during low temperature pouring, is changed to a globular structure when held at a semisolid temperature for sufficiently long holding time. With regard to the globulization mechanism of the primary α-phase, local melting is considered to take place at the neck of equiaxed dendrites, leading to the separation of small new particles during continuous cooling. These newly formed particles eventually grow during isothermal holding in the semisolid temperature by obeying theD3=Kt kinetic law, which suggests coarsening by Ostwald ripening.
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| 40. |
- Jiang, Z. K, et al.
(författare)
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Studies on radiative lifetimes in the 4d10ns2S and 4d10nd2D sequences of neutral silver
- 1990
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Ingår i: Zeitschrift für Physik D Atoms, Molecules and Clusters. - 0178-7683. ; 17:1, s. 1-4
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Tidskriftsartikel (refereegranskat)abstract
- We have performed lifetime measurements in the sequences of2S1/2 and2D3/2 states for the alkali-like 4d10 ns,nd configurations of neutral silver. Selective stepwise excitations from the 4d10 5s2S1/2 ground state were performed using two pulsed dye lasers. Optical transients were recorded and evaluated with regard to the decay time. The lifetime results are compared with those of a theoretical study in which a model potential has been used to describe the polarisation of the 4d shell.
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