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Sökning: WFRF:(Steen V)

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61.
  • Dey, D K, et al. (författare)
  • Body mass index, weight change and mortality in the elderly. A 15 y longitudinal population study of 70 y olds
  • 2024
  • Ingår i: European Journal of Clinical Nutrition. - : Nature Publishing Group. - 0954-3007 .- 1476-5640. ; 55:6, s. 482-492
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: To examine the relationship between body mass index (BMI) at age 70, weight change between age 70 and 75, and 15 y mortality. DESIGN: Cohort study of 70-y-olds. SETTING: Geriatric Medicine Department, Göteborg University, Sweden. SUBJECTS: A total of 2628 (1225 males and 1403 females) 70-y-olds examined in 1971--1981 in Gothenburg, Sweden. RESULTS: The relative risks (RRs) for 15 y mortality were highest in the lowest BMI quintiles of males 1.20 (95% CI 0.96--1.51) and females 1.49 (95% CI 1.14--1.96). In non-smoking males, no significant differences were observed across the quintiles for 5, 10 and 15 y mortality. In non-smoking females, the highest RR (1.58, 95% CI 1.15--2.16) for 15 y mortality was in the lowest quintile. After exclusion of first 5 y death, no excess risks were found in males for following 5 and 10 y mortality across the quintiles. In females, a U-shaped relation was observed after such exclusions. BMI ranges with lowest 15 y mortality were 27--29 and 25--27 kg/m(2) in non-smoking males and females, respectively. A weight loss of > or = 10% between age 70 and 75 meant a significantly higher risk for subsequent 5 and 10 y mortality in both sexes relative to individuals with 'stable' weights. CONCLUSION: Low BMI and weight loss are risk factors for mortality in the elderly and smoking habits did not significantly modify that relationship. The BMI ranges with lowest risks for 15 y mortality are relatively higher in elderly. Exclusion of early deaths from the analysis modified the weight-mortality relationship in elderly males but not in females.
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62.
  • Dey, D K, et al. (författare)
  • Height and body weight in the elderly. I. A 25-year longitudinal study of a population aged 70 to 95 years
  • 2024
  • Ingår i: European Journal of Clinical Nutrition. - : Nature Publishing Group. - 0954-3007 .- 1476-5640. ; 53:12, s. 905-914
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: To describe longitudinal changes in height and body weight between the ages of 70 and 95 y. DESIGN : Longitudinal cohort study with representative sample of 70-y-olds. SETTING: Department of Geriatric Medicine, Göteborg University, Sweden. SUBJECTS: 449 males and 524 females, aged 70 y, living in Göteborg were examined in 1971-72 and this study population participated on 11 occasions during a 25-year follow-up. RESULTS: Mean height decreased 4 and 4.9 cm in males and females respectively and the trend was significant between the ages of 70 and 95 y in both sexes. Between 70 and 75 y of age, a significant difference was found between quintiles of body height where in the highest quintile height was lowered by 0.4 and 0. 3 cm/y, in males and females respectively, and in the lowest quintile by 0.1 cm/y in both sexes. Mean body weight decreased 3.2 and 5.1 kg in males and females respectively, from age 70 to 95 y. The trend was significant over 22 and 20 y for males and females, respectively.Between the ages of 70 and 80 y, individuals in highest quintile of body weight decreased at a rate of 0.8 and 0.6 kg/y, three times higher than those in lowest quintile. Due to the decrease in both height and weight over time, body mass index (BMI) was less affected. CONCLUSION: Height, body weight and BMI decreased significantly in both sexes after age 70 y, and there was a gender difference in the trend. The results can be used as reference data for Swedish elderly and might be of importance to the understanding of anthropometry with the ageing process.
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63.
  • Dherbecourt, J. B., et al. (författare)
  • Design and pre-development of an airborne multi-species differential absorption Lidar system for water vapor and HDO isotope, carbon dioxide, and methane observation
  • 2021
  • Ingår i: Proceedings of SPIE - The International Society for Optical Engineering. - : SPIE-Intl Soc Optical Eng.
  • Konferensbidrag (refereegranskat)abstract
    • We report on the current design and preliminary developments of the airborne Lidar Emitter and Multi-species greenhouse gases Observation iNstrument (LEMON), which is aiming at probing H2O and its isotope HDO at 1982 nm, CO2 at 2051 nm, and potentially CH4 at 2290 nm, with the Differential Absorption Lidar method (DIAL). The infrared emitter is based on the combination of two Nested Cavity OPOs (NesCOPOs) with a single optical parametric amplifier (OPA) line for high-energy pulse generation. This configuration is enabled by the use of high-aperture periodically poled KTP crystals (PPKTP), which provide efficient amplification in the spectral range of interest around 2 μm with slight temperature adjustments. The parametric stages are pumped with a Nd:YAG laser providing 200 mJ nanosecond double pulses at 75 Hz. According to parametric conversion simulations supported by current laboratory experiments, output energies in the 40 - 50 mJ range are expected in the extracted signal beam whilst maintaining a good beam quality (M2 < 2). The ruler for all the optical frequencies involved in the system is planned to be provided by a GPS referenced frequency comb with large mode spacing (1 GHz) against which the emitter output pulses can be heterodyned. The frequency precision measurement is expected to be better than 200 kHz for the optical frequencies of interest. The presentation will give an overview of the key elements of design and of preliminary experimental characterizations of sub-systems building blocks. 
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64.
  • Dherbecourt, J. B., et al. (författare)
  • Lidar Emitter and Multi-species greenhouse gases Observation iNstrument (LEMON) : advances on a multi-species differential absorption Lidar system
  • 2022
  • Ingår i: 73rd International Astronautical Congress, IAC 2022. - : International Astronautical Federation, IAF.
  • Konferensbidrag (refereegranskat)abstract
    • In the frame of LEMON project (Lidar Emitter and Multi-species greenhouse gases Observation iNstrument - European Union's Horizon 2020 research and innovation program, GA n°821868), we are developing a multi-species differential absorption Lidar (DIAL). The goal is to benefit from innovative technological developments in terms of optical emitter, spectral reference, to be able to address H2O and its isotope HDO at 1982 nm, CO2 at 2051 nm, and potentially CH4 at 2290 nm, for future ground-based range-resolved DIAL sensing, and with the prospect of future airborne integrated-path DIAL (IPDA). The infrared emitter is based on the combination of two specific, patented, no-seeder Nested Cavity OPOs (NesCOPOs) coupled to a single optical parametric amplifier (OPA) line for high energy pulses generation. Specific developments are also pursued on the frequency reference for the emitter, which is planned to be provided by a GPS referenced frequency comb against which the emitter output pulses can be heterodyned. Besides the instrument design, specific tests experiments have been carried out, covering a wide panel of activities: radiation testing of some critical components to assess the potential of some key components for future space applications, emitter and frequency reference testing, preliminary DIAL tests with laboratory test-beds and comparison with specific in-situ calibration instruments as well as additional innovative techniques evaluation for the emitter. The final instrument design was carried out and the sub-units are now being built.
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67.
  • Frenneaux, M, et al. (författare)
  • Hemodynamics of cardiac arrest.
  • 2007
  • Ingår i: Cardiac arrest. The science and practice of resuscitation medicine. - 9780521847001 ; , s. 347-368
  • Bokkapitel (refereegranskat)
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70.
  • Guðlaugsdóttir, H., et al. (författare)
  • The influence of volcanic eruptions on weather regimes over the North Atlantic simulated by ECHAM5/MPI-OM ensemble runs from 800 to 2000 CE
  • 2018
  • Ingår i: Atmospheric Research. - : Elsevier BV. - 0169-8095. ; 213, s. 211-223
  • Tidskriftsartikel (refereegranskat)abstract
    • The volcanic fingerprint on the winter North Atlantic atmospheric circulation and climate is analyzed in six ensemble runs of ECHAM5/MPI-OM covering 800–2000 CE, both for equatorial and Northern Hemisphere (NH) eruptions. Large volcanic eruptions influence climate on both annual and decadal time scales due to dynamic interactions of different climate components in the Earth's system. It is well known that the North Atlantic Oscillation (NAO) tends to shift towards its positive phase during winter in the first 1–2 years after large tropical volcanic eruptions, causing warming over Europe, but other North Atlantic weather regimes have received less attention. Here we investigate the four dominant weather regimes in the North Atlantic: The negative and positive phase of NAO as well as the Atlantic Ridge, Scandinavian blocking. The volcanic fingerprint is detected as a change in the frequency of occurrence and anomalies in the wind and temperature fields as well as in the sea ice cover. We observe a strong significant increase in the frequency of Atlantic Ridge in the second year after equatorial eruptions that precede the NAO+ detected in year 3–5 as a result of a strong zonal wind anomalies in year 1–2. Evidence for a stronger polar vortex is detected in years 12–14 where NAO+ is detected both as a frequency increase and in the wind and temperature fields. A short-term response is also detected 2–4 years after NH eruptions. The longterm signal after NH eruptions indicate a weak polar vortex around a decade after an eruption. Although the signal after NH eruptions is weaker our results stress the need for further studies. The simulated atmospheric response recorded in ECHAM5 after volcanic eruptions suggest a more dynamic response than previously thought. The methodology used can also be applied to other forcing scenario, for example for future climate projections where the aim is to search for a long-term climate signal.
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