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Sökning: WFRF:(Sullivan PF)

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61.
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62.
  • BULIK, CM, et al. (författare)
  • Temperament in eating disorders
  • 1995
  • Ingår i: The International journal of eating disorders. - 0276-3478. ; 17:3, s. 251-261
  • Tidskriftsartikel (refereegranskat)
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63.
  • Bulik, CM, et al. (författare)
  • The Eating Disorders Genetics Initiative (EDGI): study protocol
  • 2021
  • Ingår i: BMC psychiatry. - : Springer Science and Business Media LLC. - 1471-244X. ; 21:1, s. 234-
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundThe Eating Disorders Genetics Initiative (EDGI) is an international investigation exploring the role of genes and environment in anorexia nervosa, bulimia nervosa, and binge-eating disorder.MethodsA total of 14,500 individuals with eating disorders and 1500 controls will be included from the United States (US), Australia (AU), New Zealand (NZ), and Denmark (DK). In the US, AU, and NZ, participants will complete comprehensive online phenotyping and will submit a saliva sample for genotyping. In DK, individuals with eating disorders will be identified by the National Patient Register, and genotyping will occur using bloodspots archived from birth. A genome-wide association study will be conducted within EDGI and via meta-analysis with other data from the Eating Disorders Working Group of the Psychiatric Genomics Consortium (PGC-ED).DiscussionEDGI represents the largest genetic study of eating disorders ever to be conducted and is designed to rapidly advance the study of the genetics of the three major eating disorders (anorexia nervosa, bulimia nervosa, and binge-eating disorder). We will explicate the genetic architecture of eating disorders relative to each other and to other psychiatric and metabolic disorders and traits. Our goal is for EDGI to deliver “actionable” findings that can be transformed into clinically meaningful insights.Trial registrationEDGI is a registered clinical trial: clinicaltrials.govNCT04378101.
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64.
  • Bulik, CM, et al. (författare)
  • The genetics of anorexia nervosa
  • 2007
  • Ingår i: Annual review of nutrition. - : Annual Reviews. - 0199-9885 .- 1545-4312. ; 27, s. 263-275
  • Tidskriftsartikel (refereegranskat)abstract
    • Anorexia nervosa is a perplexing illness marked by low body weight and persistent fear of weight gain. Anorexia nervosa has the highest mortality rate of any psychiatric disease. Historically, anorexia nervosa was viewed as a disorder primarily influenced by sociocultural factors; however, over the past decade, this perception has been challenged. Family studies have consistently demonstrated that anorexia nervosa runs in families. Twin studies have underscored the contribution of additive genetic factors to the observed familial aggregation. With these bodies of literature as a starting point, we evaluate critically the current state of research on molecular genetic studies of anorexia nervosa and provide guidance for future research.
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  • Resultat 61-70 av 331

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