| 11. |
- Granroth, Sari, et al.
(författare)
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Investigation of interface properties of Ni/Cu multilayers by high kinetic energy photoelectron spectroscopy
- 2009
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Ingår i: Physical Review B (Condensed Matter and Materials Physics). - 1098-0121 .- 1550-235X. ; 80:9
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Tidskriftsartikel (refereegranskat)abstract
- High kinetic-energy photoelectron spectroscopy (HIKE) or hard x-ray photoelectron spectroscopy has been used to investigate the alloying of Ni/Cu (100) multilayers. Relative intensities of the corelevels and their chemical shifts derived from binding energy changes are shown to give precise information on physicochemical properties and quality of the buried layers. Interface roughening, including kinetic properties such as the rate of alloying, and temperature effects on the processes can be analyzed quantitatively. Using HIKE, we have been able to precisely follow the deterioration of the multilayer structure at the atomic scale and observe the diffusion of the capping layer into the multilayer structure which in turn is found to lead to a segregation in the ternary system. This is of great importance for future research on multilayered systems of this kind. Our experimental data are supplemented by first-principles theoretical calculations of the core-level shifts for a ternary alloy to allow for modeling of the influence of capping materials on the chemical shifts.
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| 12. |
- Haberska, Karolina, et al.
(författare)
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Activity of lactoperoxidase when adsorbed on protein layers
- 2008
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Ingår i: Talanta. - : Elsevier. - 0039-9140 .- 1873-3573. ; 76:5, s. 1159-1164
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Tidskriftsartikel (refereegranskat)abstract
- Lactoperoxidase (LPO) is an enzyme, which is used as an antimicrobial agent in a number of applications, e.g., food technology. In the majority of applications LPO is added to a homogeneous product phase or immobilised on product surface. In the latter case, however, the measurements of LPO activity are seldom reported. In this paper we have assessed LPO enzymatic activity on bare and protein modified gold surfaces by means of electrochemistry. It was found that LPO rapidly adsorbs to bare gold surfaces resulting in an amount of LPO adsorbed of 2.9 mg/m2. A lower amount of adsorbed LPO is obtained if the gold surface is exposed to bovine serum albumin, bovine or human mucin prior to LPO adsorption. The enzymatic activity of the adsorbed enzyme is in general preserved at the experimental conditions and varies only moderately when comparing bare gold and gold surface pretreated with the selected proteins. The measurement of LPO specific activity, however, indicate that it is about 1.5 times higher if LPO is adsorbed on gold surfaces containing a small amount of preadsorbed mucin in comparison to the LPO directly adsorbed on bare gold.
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| 13. |
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| 14. |
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| 15. |
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| 16. |
- Jakobsson, Martin, et al.
(författare)
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Reconstructing the Younger Dryas ice dammed lake in the Baltic Basin: Bathymetry, area and volume
- 2007
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Ingår i: Global and Planetary Change. - : Elsevier BV. - 1872-6364 .- 0921-8181. ; 57:3-4, s. 355-370
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Tidskriftsartikel (refereegranskat)abstract
- A digital 3D-reconstruction of the Baltic Ice Lake's (BIL) configuration during the termination of the Younger Dryas cold phase (ca. 11700 cal. yr BP) was compiled using a combined bathymetric-topographic Digital Terrain Model (DTM), Scandinavian ice sheet limits, Baltic Sea Holocene bottom sediment thickness information, and a paleoshoreline database maintained at the Lund University. The bathymetric-topographic DTM, assembled from publicly available data sets, has a resolution of 500 X 500 m on Lambert Azimuthal Equal Area projection allowing area and volume calculations of the BIL to be made with an unprecedented accuracy. When the damming Scandinavian ice sheet margin eventually retreated north of Mount Billingen, the high point in terrain of Southern central Sweden bordering to lower terrain further to the north, the BIL was catastrophically drained resulting in a 25 m drop of the lake level. With our digital reconstruction, we estimate that approximately 7800 km(3) of water drained during this event and that the ice dammed lake area was reduced by ca. 18%. Building on previous results suggesting drainage over 1 to 2 years, our lake volume calculations imply that the freshwater flux to the contemporaneous sea in the west was between about 0.12 and 0.25 Sv. The BIL reconstruction provides new detailed information on the paleogeography in the area of southern Scandinavia, both before and after the drainage event, with implications for interpretations of geological records concerning the post-glacial environmental development. (c) 2007 Elsevier B.V All rights reserved.
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| 17. |
- Johansson, Erik, et al.
(författare)
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Valence Electronic Structure Of Ruthenium Based Complexes Probed By Photoelectron Spectroscopy At High Kinetic Energy (Hike) And Modeled By Dft Calculations
- 2008
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Ingår i: Chemical Physics Letters. - : Elsevier BV. - 0009-2614 .- 1873-4448. ; 464:4-6, s. 192-197
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Tidskriftsartikel (refereegranskat)abstract
- The valence electronic structure of a series of molecular films containing ruthenium polypyridine complexes has been investigated by photoelectron spectroscopy (PES) at high kinetic energy (HIKE) using hard X-ray. The experiment shows the possibility to experimentally probe the metal contribution to the valence spectra in a bulk sensitive mode. Specifically to directly follow the Ru 4d contribution to the highest occupied molecular orbitals of such complexes. The experimental spectra are accurately modeled by DFT calculations only if a crystal structure environment is taken into account showing the importance of intermolecular interaction for modeling the electronic structure of such complexes.
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| 18. |
- Jormfeldt, Henrika
(författare)
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Dimensions of Health among Patients in Mental Health Services
- 2007
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Empirical studies focusing on the subjective experience of health among patients in contact with the mental health services are rare and most questionnaires are based on a medical model that emphasizes objectively observed disease-oriented health indicators. In studies I and II perceptions of the concept of health among patients and nurses in mental health services were explored and described using a phenomenographic approach. The perceptions and description categories that emerged from these studies were transformed into a number of items forming a questionnaire intended to measure subjectively experienced health among patients in mental health services. In study III, a randomly selected sample was used to test the psychometric properties of the new Health Questionnaire. A factor analysis revealed three factors labelled Autonomy, Social Involvement and Comprehensibility. The purpose of study IV was to examine the construct validity of the Health Questionnaire. The hypothesis was that subjectively experienced health would be positively associated to self-esteem, empowerment and quality of life, and negatively associated to psychiatric symptoms, perceived stigmatization experiences and perceived attitudes of devaluation and discrimination. This hypothesis was mainly confirmed insofar that overall health was positively correlated to self-esteem, empowerment and quality of life and negatively correlated to symptoms, attitudes of devaluation and discrimination and rejection experiences. The results of this thesis show that health is more than just an absence of disease and support a focus on health promotion interventions in mental health care.
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| 19. |
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| 20. |
- Karlsson, Beatrice, et al.
(författare)
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Quasispecies dynamics and molecular evolution of human norovirus capsid P region during chronic infection
- 2009
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Ingår i: Journal of General Virology. - : Microbiology Society. - 0022-1317 .- 1465-2099. ; 90:2, s. 432-441
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Tidskriftsartikel (refereegranskat)abstract
- In this novel study, we have for the first time identified evolutionarily conserved capsid residues in an individual chronically infected with norovirus (GGII.3). From 2000 to 2003, a total of 147 P1-1 and P2 capsid sequences were sequenced and investigated for evolutionarily conserved and functionally important residues by the evolutionary trace (ET) algorithm. The ET algorithm revealed more absolutely conserved residues (ACR) in the P1-1 domain (47/53, 88 %) as compared with the P2 domain (86/133, 64 %). The capsid P1-1 and P2 domains evolved in time-dependent manner, with a distinct break point observed between autumn/winter of year 2000 (isolates P1, P3 and P5) and spring to autumn of year 2001 (isolates P11, P13 and P15), which presumably coincided with a change of clinical symptoms. Furthermore, the ET analysis revealed a similar receptor-binding pattern as reported for Norwalk and VA387 strains, with the CS-4 and CS-5 patch (Norwalk strain) including residues 329 and 377 and residues 306 and 310, respectively, all being ACR in all partitions. Most interesting was that residues 343, 344, 345, 374, 390 and 391 of the proposed receptor A and B trisaccharide binding site (VA387 strain) within the P2 domain remained ACR in all partitions, presumably because there was no selective advantage to alter the histo blood group antigens (HBGA) receptor binding specificity. In conclusion, this study provides novel insights to the evolutionary process of norovirus during chronic infection.
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