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Sökning: WFRF:(Terry P)

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  • Terry, P, et al. (författare)
  • Prospective study of major dietary patterns and colorectal cancer risk in women
  • 2001
  • Ingår i: American Journal of Epidemiology. - Karolinska Inst, Dept Med Epidemiol, S-10521 Stockholm, Sweden. Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA. Univ Connecticut, Ctr Hlth, Dept Community Med, Farmington, CT 06032 USA. : OXFORD UNIV PRESS INC. - 0002-9262 .- 1476-6256. ; 154:12, s. 1143-1149
  • Tidskriftsartikel (refereegranskat)abstract
    • A number of prospective cohort studies have examined the relations of individual dietary variables to risk of colorectal cancer. Few studies have addressed the broader eating patterns that reflect many dietary exposures working together. Using data from a prospective study of 61,463 women, with an average follow-up period of 9.6 years (between 1987 and 1998) and 460 incident cases of colorectal cancer, the authors conducted a factor analysis to identify and examine major dietary patterns in relation to colorectal cancer risk. Using proportional hazards regression to estimate relative risks, the authors found no clear association between a "Western," "healthy," or "drinker" dietary pattern and colorectal cancer risk. However, the data suggested that consuming low amounts of foods that constitute a "healthy" dietary pattern may be associated with increased risks of colon and rectal cancers. An inverse association with the "healthy" dietary pattern was found among women under age 50 years, although the number of cancers in this age group was limited and interpretation of this finding should be cautious. In this age group, relative risks for women in increasing quintiles of the "healthy" dietary pattern, compared with the lowest quintile, were 0.74 (95% confidence interval (Cl): 0.41, 1.31), 0.69 (95% Ci: 0.39, 1.24), 0.59 (95% Cl: 0.32, 1.07), and 0.45 (95% Cl: 0.23, 0.88) (p for trend = 0.03). The role of overall eating patterns in predicting colorectal cancer risk requires further investigation.
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  • Terry, P, et al. (författare)
  • [Reply: it can't be worse!]
  • 2000
  • Ingår i: Lakartidningen. ; 97
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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199.
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200.
  • Terry, P, et al. (författare)
  • Tea consumption and the risk of colorectal cancer in Sweden
  • 2001
  • Ingår i: Nutrition and Cancer. - Karolinska Inst, Dept Med Epidemiol, SE-17177 Stockholm, Sweden. : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. - 0163-5581 .- 1532-7914. ; 39:2, s. 176-179
  • Tidskriftsartikel (refereegranskat)abstract
    • The association between tea drinking and colorectal cancer risk remains unclear. The evidence for black tea is sparse but may indicate an increased risk with regular use. Because black tea is a common beverage in many populations, the significant twofold increased risk of colon cancer recently reported from a large prospective cohort of male Finnish smokers is disconcerting. Using Cox proportional hazards models to estimate relative risks, we examined this association in a large, population-based prospective cohort study in Sweden. During an average 9.6 years of follow-up of our cohort of 61,463 women (588,270 person yr), we observed 460 incident cases of colorectal cancer (291 colon, 159 rectal, and 10 with both colon and rectal cancer). We observed no association between tea consumption and combined colorectal cancers in age- or multivariate-adjusted models. With the use of collapsed exposure categories, the multivariate-adjusted relative risk for the highest exposure (greater than or equal to2 cups/day) compared with the lowest (never or seldom) was 0.97 (95% confidence interval = 0.63-1.48, p for trend = 0.34). Examining the association by cancer subsite, we observed no association between tea consumption and proximal, distal, or combined colon cancers. We did, however, observe a nonsignificant positive association with rectal cancers, which became stronger and statistically significant among women greater than or equal to 65 years of age at baseline. Our data do not support the strong, dose-dependent positive association with colon cancer found in the Finnish study.
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