| 51. |
- Sandlund, Marlene, 1972-, et al.
(författare)
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Using motion interactive games to promote physical activity and enhance motor performance in children with cerebral palsy
- 2011
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Ingår i: Developmental Neurorehabilitation. - : Taylor & Francis. - 1751-8423 .- 1751-8431. ; 14:1, s. 15-21
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To explore the feasibility of using low-cost motion interactive games as a home-based intervention for children with cerebral palsy (CP).Methods: Fourteen children with CP, 6–16 years old, practiced with the EyeToy for PlayStation2® in their homes during 4 weeks. Outcome measures were physical activity monitors, Movement Assessment Battery for Children-2 (mABC-2), Bruininks-Oseretsky Test of Motor Proficiency (sub-test 5 : 6), 1 Minute Walk Test and gaming diaries.Results: Motivation for practice and compliance of training were high. The children's physical activity increased during the intervention and activity monitors were feasible to use, although data loss may be a concern. According to mABC-2 the children's motor performance improved, but there were both floor and ceiling effects. The two additional motor tests showed only non-significant progress.Conclusion: It is highly feasible to use motion interactive games in home rehabilitation for children with CP. Specific motor effects need to be further explored.
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| 52. |
- Turcot, Valerie, et al.
(författare)
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
- 2018
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Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 50:1, s. 26-41
-
Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains challenging. Here we combined data from 718,734 individuals to discover rare and low-frequency (minor allele frequency (MAF) < 5%) coding variants associated with BMI. We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHE, RAPGEF3, RAB21, ZFHX3, ENTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in genes (MC4R and KSR2) previously observed to be mutated in extreme obesity and 2 variants were in GIPR. The effect sizes of rare variants are similar to 10 times larger than those of common variants, with the largest effect observed in carriers of an MC4R mutation introducing a stop codon (p.Tyr35Ter, MAF = 0.01%), who weighed similar to 7 kg more than non-carriers. Pathway analyses based on the variants associated with BMI confirm enrichment of neuronal genes and provide new evidence for adipocyte and energy expenditure biology, widening the potential of genetically supported therapeutic targets in obesity.
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| 53. |
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| 54. |
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| 55. |
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| 56. |
- Winge, Monica, et al.
(författare)
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A New Care Concept : Making Collaborative Home Care Work
- 2007
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Ingår i: Proceedings of the 6th International Conference on Perspectives in Business Information Research. - Tampere : Tampere University. - 9789514471216 ; , s. 158-169
-
Konferensbidrag (refereegranskat)abstract
- In this paper we discuss the fact that more and more patients are treated in their homes by a set of organizations, sometimes with different ownership, we explore how this poses new and heavy demands on health care and home service staff to communicate and to collaborate. We investigate the need for improved communication and collaboration on different managerial and operational levels. In particular we point to the need for managers in different organizations to agree on ways of communicating and collaborating between the operational level and the importance of this during procurement of home care services. As a result the paper suggests a number of methodological measures, strategies and IT solutions, to support organizational development, coordination and collaboration.
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| 57. |
- Winge, Monica, et al.
(författare)
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A New Care Concept : Making Collaborative Home Care Work
- 2007
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Ingår i: Proceedings from the 6th International Conference on Perspectives in Business Informatics Research. - Tampere : Department of Computer Science, University of Tampere. - 9789514471216 ; , s. 158-169
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Konferensbidrag (refereegranskat)
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| 58. |
- Winge, Monica, et al.
(författare)
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Co-Care : Collaborative health and social care
- 2008
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Ingår i: Proceedings of the 13th International Symposium for Health Information Management Research. - : Massey University. - 9780473141738 ; , s. 113-124
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Konferensbidrag (refereegranskat)
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| 59. |
- Winge, Monica, et al.
(författare)
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CO-CARE - Collaborative Health and Social Care
- 2008
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Ingår i: Proceedings of the 13th International Symposium for Health Information Management Research. - Palmerston North, New Zealand : Massey University. - 9780473141738 ; , s. 113-124
-
Konferensbidrag (refereegranskat)abstract
- In this paper we discuss the fact that more and more patients are treated in their homes by a set of organizations, sometimes with different ownership. We explore how this poses new and stronger demands on health care and home service staff, as well as on different managerial and operational levels, to improve their communication and collaboration. We emphasize the need for managers in different organizations to agree on ways and forms of communication and collaboration between the operational levels, and the particular importance of this during procurement of home care services. As a result a number of methodological measures, strategies and IT solutions to support organizational development, coordination and collaboration are suggested.
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| 60. |
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