↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Tyck till om SwePub Sök här!

Träfflista för sökning "WFRF:(Westerlund M.) "

Sökning: WFRF:(Westerlund M.)

Resultat 61-70 av 227

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
61.	Almaqwashi, A. A., et al. (författare) Resolving the DNA Binding Mode of a Rotationally Flexible Binuclear Ruthenium Complex 2015 Ingår i: Biophysical Journal. - 0006-3495 .- 1542-0086. ; 108:2, s. 396A-396A Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
62.	Almaqwashi, A. A., et al. (författare) Strong DNA deformation required for extremely slow DNA threading intercalation by a binuclear ruthenium complex 2014 Ingår i: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 42:18, s. 11634-11641 Tidskriftsartikel (refereegranskat)abstract DNA intercalation by threading is expected to yield high affinity and slow dissociation, properties desirable for DNA-targeted therapeutics. To measure these properties, we utilize single molecule DNA stretching to quantify both the binding affinity and the force-dependent threading intercalation kinetics of the binuclear ruthenium complex Delta, Delta-[mu-bidppz-(phen)(4)Ru-2]4(+) (Delta, Delta-P). We measure the DNA elongation at a range of constant stretching forces using optical tweezers, allowing direct characterization of the intercalation kinetics as well as the amount intercalated at equilibrium. Higher forces exponentially facilitate the intercalative binding, leading to a profound decrease in the binding site size that results in one ligand intercalated at almost every DNA base stack. The zero force Delta, Delta-P intercalation K-d is 44 nM, 25-fold stronger than the analogous mono-nuclear ligand (Delta-P). The force-dependent kinetics analysis reveals a mechanism that requires DNA elongation of 0.33 nm for association, relaxation to an equilibrium elongation of 0.19 nm, and an additional elongation of 0.14 nm from the equilibrium state for dissociation. In cells, a molecule with binding properties similar to Delta, Delta-P may rapidly bind DNA destabilized by enzymes during replication or transcription, but upon enzyme dissociation it is predicted to remain intercalated for several hours, thereby interfering with essential biological processes.
63.	Altai, M., et al. (författare) A novel method for conjugation of PNA to antibodies for radionuclide based pretargeting : proof of principal 2018 Ingår i: European Journal of Nuclear Medicine and Molecular Imaging. - : SPRINGER. - 1619-7070 .- 1619-7089. ; 45, s. S648-S648 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
64.	Altai, M., et al. (författare) Design and evaluation oflactosaminated cetuximabas a clearing agent for antibody-based PNA-mediated pretargeting 2020 Ingår i: European Journal of Nuclear Medicine and Molecular Imaging. - : SPRINGER. - 1619-7070 .- 1619-7089. ; 47:SUPPL 1, s. S343-S344 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
65.	Altria, KD, et al. (författare) Separation of a range of cations by nonaqueous capillary electrophoresis using indirect and direct detection 1998 Ingår i: J CHROMATOGRAPHY B. ; 714, s. 99- Tidskriftsartikel (refereegranskat)
66.	Andreeva, Elena, et al. (författare) Depressive symptoms as a cause and effect of job loss in men and women : evidence in the context of organisational downsizing from the Swedish Longitudinal Occupational Survey of Health 2015 Ingår i: BMC Public Health. - : Springer Science and Business Media LLC. - 1471-2458. ; 15 Tidskriftsartikel (refereegranskat)abstract Background: Few studies have examined depression as both a cause and effect of unemployment, but no prior work investigated these relationships in the context of organisational downsizing. We explored whether the exposure to downsizing is associated with subsequent depression (social causation), and whether pre-existing depression increases the risk of being laid off when organisations downsize (health selection). Methods: Two successive waves of the nationally representative Swedish Longitudinal Occupational Survey of Health represented the baseline (2008) and follow-up (2010) of this study. Analyses included 196 workers who lost their jobs through downsizing, 1462 layoff survivors remaining in downsized organisations and 1845 employees of non-downsized workplaces. The main outcomes were: (1) Depressive symptoms at follow-up, assessed with a brief subscale from the Symptom Checklist 90, categorised by severity levels (major depression, less severe symptoms and no depression) and analysed in relation to earlier downsizing exposure; (2) Job loss in persons with downsizing in relation to earlier depressive symptoms. The associations were assessed by means of multinomial logistic regression. Results: Job loss consistently predicted subsequent major depression among men and women, with a somewhat greater effect size in men. Surviving a layoff was significantly associated with subsequent major depression in women but not in men. Women with major depression have increased risks of exclusion from employment when organisations downsize, whereas job loss in men was not significantly influenced by their health. Conclusions: The evidence from this study suggests that the relative importance of social causation and health selection varies by gender in the context of organisational downsizing. Strategies for handling depression among employees should be sensitive to gender-specific risks during layoffs. Policies preventing social exclusion can be important for female workers at higher risk of depression.
67.	Anvret, A, et al. (författare) Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease 2012 Ingår i: Behavioural brain research. - : Elsevier BV. - 1872-7549 .- 0166-4328. ; 227:1, s. 252-257 Tidskriftsartikel (refereegranskat)
68.	Anvret, A, et al. (författare) Genetic Screening of the Mitochondrial Rho GTPases MIRO1 and MIRO2 in Parkinson's Disease 2012 Ingår i: The open neurology journal. - 1874-205X. ; 6, s. 1-5 Tidskriftsartikel (refereegranskat)
69.	Anvret, A, et al. (författare) Modeling Parkinson's Disease in Adh1 and Adh1/4 Knockout Mice 2010 Ingår i: MOVEMENT DISORDERS. - 0885-3185. ; 25, s. S632-S632 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
70.	Anvret, A, et al. (författare) Variations of the CAG trinucleotide repeat in DNA polymerase γ (POLG1) is associated with Parkinson's disease in Sweden 2010 Ingår i: Neuroscience letters. - : Elsevier BV. - 1872-7972 .- 0304-3940. ; 485:2, s. 117-120 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 61-70 av 227

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (186); konferensbidrag (32); forskningsöversikt (3); annan publikation (2); rapport (1); doktorsavhandling (1); visa fler...; bokkapitel (1); licentiatavhandling (1); visa färre...

Typ av innehåll: refereegranskat (176); övrigt vetenskapligt/konstnärligt (48); populärvet., debatt m.m. (3)

Författare/redaktör: Westerlund, M. (48); Westerlund, Fredrik, ... (34); Westerlund, Hugo (30); Galter, D. (21); Theorell, Töres (20); Westerholm, Peter J. ... (18); visa fler...; Nordin, Maria (17); Westerlund, Annie M. (17); Delemotte, Lucie (16); Vahtera, J. (16); Knutsson, Anders (16); Rouzina, I. (16); Belin, AC (15); Rugulies, Reiner (15); Pentti, Jaana (14); Vahtera, Jussi (14); Virtanen, Marianna (13); Kivimäki, Mika (13); Kivimäki, M (13); Lincoln, Per, 1958 (13); Madsen, Ida E. H. (13); Olson, L (12); Alfredsson, Lars (12); Oksanen, Tuula (12); Williams, M. C. (12); Westerlund, E (12); Dragano, Nico (12); Goldberg, M (11); Zins, M. (11); Westerlund, H. (11); Westerlund, D (11); Magnusson Hanson, Li ... (11); Singh-Manoux, Archan ... (11); Koskenvuo, Markku (11); Tenhunen, Hannu (10); Anvret, A. (10); Burr, Hermann (10); Borritz, Marianne (10); Nielsen, Martin L. (10); Pejtersen, Jan H. (10); Leineweber, Constanz ... (9); Sydow, O. (9); Head, J (9); Westerlund, Anna, 19 ... (9); Steptoe, Andrew (9); Hamer, Mark (9); Batty, G. David (9); Ferrie, Jane E (9); Salo, Paula (9); Bjorner, Jakob B. (9); visa färre...

Lärosäte: Karolinska Institutet (98); Uppsala universitet (54); Stockholms universitet (47); Chalmers tekniska högskola (37); Göteborgs universitet (36); Kungliga Tekniska Högskolan (35); visa fler...; Umeå universitet (21); Jönköping University (19); Mittuniversitetet (17); Lunds universitet (7); Linköpings universitet (3); Högskolan i Gävle (2); Högskolan i Skövde (2); Mälardalens universitet (1); Örebro universitet (1); Sveriges Lantbruksuniversitet (1); visa färre...

Språk: Engelska (224); Svenska (3)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (70); Naturvetenskap (60); Teknik (18); Samhällsvetenskap (12); Lantbruksvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy