| 291. |
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| 292. |
- Wiklund, Martin, et al.
(författare)
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On-chip acoustic sample preparation for cell studies and diagnostics
- 2013
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Ingår i: Proceedings of Meetings on Acoustics. - : Acoustical Society of America (ASA). ; , s. 1-3
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Konferensbidrag (refereegranskat)abstract
- We describe a novel platform for acoustic sample preparation in microchannels and microplates. The utilized method is based on generating a multitude of acoustic resonances at a set of different frequencies in microstructures, in order to accurately control the migration and positioning of particles and cells suspended in fluid channels and chambers. The actuation frequencies range from 30 kHz to 7 MHz, which are applied simultaneously and/or in sweeps. We present two devices: A closed microfluidic chip designed for pre-alignment, size-based separation, isolation, up-concentration and lysis of cells, and an open multi-well microplate designed for parallel aggregation and positioning of cells. Both devices in the platform are compatible with high-resolution live-cell microscopy, which is used for fluorescence-based optical characterization. Two bioapplications are demonstrated for each of the devices: The first device is used for size-selective cell isolation and lysis for DNA-based diagnostics, and the second device is used for quantifying the heterogeneity in cytotoxic response of natural killer cells interacting with cancer cells.
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| 293. |
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| 294. |
- Wiklund, Martin, 1970-
(författare)
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På spaning efter den erfarenhet som flytt : Förlusten och återkomsten av historisk erfarenhet som underliggande mönster i 1900-talets historieteori
- 2021
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Ingår i: Moderniteten som framgång och tragedi. - Lund : Nordic Academic Press. - 9789189361027 ; , s. 257-270
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- This article aims to reveal an underlying pattern in the theory of history in the 20th century: the loss and revival of historical experience. While the dominant approach of the 19th century was characterized by historical perspectives, in the 20th century practical orientation was more often characterized by ahistorical approaches. This shift can be traced to the crisis of historicism and its crisis of the relevance of history for the present. The crisis gave rise to various ahistorical perspectives on society and values. But the experiences of the 20th century and the loss of experience also motivated some historians to develop new perspectives that could regain historical experience for practical orientation. This is illustrated with examples from three directions in historical research: Reinhart Koselleck, Hans-Ulrich Wehler's Gesellschaftsgeschichte and a concept of listening to the voices of the past in memory studies. A central trajectory for the theory of history in the 20th century can thus be formulated in terms of historical experience lost and regained.
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| 295. |
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| 296. |
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| 297. |
- Wiklund, Martin, 1970-
(författare)
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"Rüsen’s response to the crisis of historicism"
- 2017
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Ingår i: Intelligere, Revista de História Intelectual. - : Universidade de Sao Paulo, Agencia USP de Gestao da Informacao Academica (AGUIA). - 2447-9020. ; 3:2, s. 90-104
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Tidskriftsartikel (refereegranskat)abstract
- Although Rüsen only discusses the crisis of historicism explicitly in his work occasionally, his general perspective on historical knowledge can be interpreted as a response to the crisis. Different responses to the crisis of historicism correspond to different interpretations of its main problems. In order to specify Rüsen’s response, a number of aspects of his perspective are pointed out as solutions to such problems. Indirectly, the analysis discloses problems that any plausible attempt to come to terms with the crisis of historicism ought to handle. By identifying differences to other contemporary responses to the crisis of historicism, the continuing relevance of Rüsen’s approach is demonstrated.
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| 298. |
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| 299. |
- Wiklund, Martin, 1938-, et al.
(författare)
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The Concept of Value Activation - Wood Properties at Different Annual Ring Orientation in Pine (Pinus Silvestris L).
- 1998
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Ingår i: Timber and Wood Composites for the Next Century.
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Konferensbidrag (refereegranskat)abstract
- An integrated R&D program called "Value Activation" has been carried out for the past eight years at the Royal Institute of Technology, Div. of Wood Technology and Processing (KTH-Trä). The concept of Value Activation is focused on the basic understanding of wood, and the fact that there are properties that are not fully exploited in conventional wood manufacturing systems to date. The strategy is to activate these inherent properties by a better understanding of the fundamental behaviour of wood, combined with new applied process technology and the development of the required manufacturing systems.The Value Activation program has so far shown that there are great possibilities of utilizing the properties of wood in a better way than our conventional wood production concept can achieve. New wood products with desirable properties can be developed. Most of these products are expected to give a greater added value to the wood. The R&D program will continue with the further development of improved products and also with the development of cost-efficient production systems for implementing the ideas from our R&D in profitable production units.Within the Value Activation program the following properties, which were judged to be the most important ones for future wood products were chosen:Aesthetic and tactile factorsControlled moisture movementsAccuracy in size and geometryNo checks and splitsStrength and hardnessThese properties are all strongly influenced by the annual ring orientation in the cross section of the sawn timber. This paper describes the influence of the annual ring orientation on these properties and how they can be improved by using a new sawing pattern.
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| 300. |
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