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Sökning: WFRF:(Yin G)

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741.
  • Yin, X., et al. (författare)
  • Towards efficient 100 Gb/s serial rate optical interconnects : A duobinary way
  • 2017
  • Ingår i: 6th IEEE Photonics Society Optical Interconnects Conference, OI 2017. - : Institute of Electrical and Electronics Engineers (IEEE). - 9781509050154 ; , s. 33-34
  • Konferensbidrag (refereegranskat)abstract
    • Recent advances in integrated opto-electronic devices and front end circuits have made it possible to efficiently transmit very high data rates over optical links for HPC/datacenter applications. This paper reviews our current progress towards serial 100-Gb/s optical interconnects, with emphasis on electrical duobinary (EDB) modulation.
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742.
  • Yin, Ying, 1983- (författare)
  • Environmental Integration in Sustainable Urban Planning from an Institutional Perspective : A Study of Swedish and Chinese Eco-City Development
  • 2014
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The continuously rising attention to and practice of eco-city development in Sweden and China, as well as the countries’ active cooperation has motivated this study and the exploration of eco-city development in these two countries. In eco-city development, diverse environmental issues may well be beyond the planning sector’s capacity and need to be resolved elsewhere by other authorities and agencies in such areas as energy, water and traffic. This may in practice require the reframing of certain institutions to ensure that relevant sector authorities, scientific institutions and actors have responsibilities for integrative tasks and can cooperate effectively.The study aims to investigate how institutional conditions affect environmental integration in urban planning. The approach used is the exploration of how different institutional conditions promote and/or hinder environmental integration by the examination of four examples of eco-city development in Sweden and China. Based on theories of institutions, Environmental Policy Integration (EPI) and sustainable urban planning, an analytical framework is used to describe institutional conditions related to formal rulemaking, informal rules and administrative management and organizations.Formal rules provide framework and legitimacy for guiding and enforcing actors in the practice of realizing environmental integration in urban planning. Meanwhile, informal rules; i.e. wills, interests, understanding and knowledge, could considerably affect the design of formal rules and how they are to be implemented. Administrative management and organization serve to realize environmental integration following the formal rules, but the informal institutional conditions of e.g. officials’ interests, understanding, knowledge and experience, as well as political support, affect the organizations’ performance and abilities for implementation, which in turn also largely depends on the specific organizational settings. All three need to be combined to achieve environmental integration in sustainable urban planning, since each one has its own strengths and weaknesses and they gradually affect each other in practices.
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743.
  • Yin, Y-G, et al. (författare)
  • Polymeric structure and solid NMR spectra of cadmuim (II) dialkyldithiophosphates (alkyl = propyl, butyl, isopropyl and isobutyl)
  • 2003
  • Ingår i: Chinese journal of chemistry. - : Wiley. - 1001-604X .- 1614-7065. ; 21:3, s. 291-295
  • Tidskriftsartikel (refereegranskat)abstract
    • By dropwise adding thio ligands to concentrated aqueous solutions of Cd(ClO4)26H2O, polymeric complexes, Cd(II) O,O′-dipropyl-dithiophosphate (1), O,O′-dibutyl- dithiophosphate (2), O,O′-diisopropyi-dithiophosphate (3) and O,O′-diisobutyl-dithiophosphate (4) were obtained. The structure of 4 was determined by X-ray diffraction analysis, showing that the metal ion sits in distorted tetrahedral sulphur coordination sphere and that the eight-membered bimetallic rings take the twist chair and boat conformations, alternately. Based on facts that the S(1)-Cd bond length [0.25099(12) nm] is shorter than the other S-Cd bond length [0.25399(12)-0.25701(18) nm] and that the S(1)-involving angles [113.45(4)°-118.43(5)°] are systematically larger than the normal angles of a tetrahedron, the ligands are hypothesized to be erratically functionalized to Cd(II). To certify the steric nonequivalence of ligands, the compounds were investigated by solid 13C, 31P and 113Cd NMR spectroscopy.
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744.
  • Yin, Y. Y., et al. (författare)
  • Quantifying Water Scarcity in Northern China Within the Context of Climatic and Societal Changes and South-to-North Water Diversion
  • 2020
  • Ingår i: Earths Future. - : American Geophysical Union (AGU). - 2328-4277. ; 8:8
  • Tidskriftsartikel (refereegranskat)abstract
    • With the increasing pressure from population growth and economic development, northern China (NC) faces a grand challenge of water scarcity, which can be further exacerbated by climatic and societal changes. The South-to-North Water Diversion (SNWD) project is designed to mitigate the water scarcity in NC. However, few studies have quantified the impact of the SNWD on water scarcity within the context of climatic and societal changes and its potential effects on economic and agricultural food in the region. We used water supply stress index (WaSSI) to quantify water scarcity within the context of environmental change in NC and developed a method to estimate the economic and agricultural impacts of the SNWD. Focuses were put on alleviating the water supply shortage and economic and agricultural benefits for the water-receiving NC. We find that societal changes, especially economic growth, are the major contributors to water scarcity in NC during 2009-2099. To completely mitigate the water scarcity of NC, at least an additional water supply of 13 billion m(3)/year (comparable to the annual diversion water by SNWD Central Route) will be necessary. Although SNWD alone cannot provide the full solution to NC's water shortage in next few decades, it can significantly alleviate the water supply stress in NC (particularly Beijing), considerably increasing the agricultural production (more than 115 Tcal/year) and bringing economic benefits (more than 51 billion RMB/year) through supplying industrial and domestic water use. Additionally, the transfer project could have impacts on the ecological environment in the exporting regions.
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745.
  • Yin, Zhaojun, et al. (författare)
  • Antitumor Humoral and T Cell Responses by Mucin-1 Conjugates of Bacteriophage Qβ in Wild-type Mice
  • 2018
  • Ingår i: ACS Chemical Biology. - : American Chemical Society. - 1554-8929 .- 1554-8937. ; 13:6, s. 1668-1676
  • Tidskriftsartikel (refereegranskat)abstract
    • Mucin-1 (MUC1) is one of the top ranked tumor associated antigens. In order to generate effective anti-MUC1 immune responses as potential anticancer vaccines, MUC1 peptides and glycopeptides have been covalently conjugated to bacteriophage Qβ. Immunization of mice with these constructs led to highly potent antibody responses with IgG titers over one million, which are among the highest anti-MUC1 IgG titers reported to date. Furthermore, the high IgG antibody levels persisted for more than six months. The constructs also elicited MUC1 specific cytotoxic T cells, which can selectively kill MUC1 positive tumor cells. The unique abilities of Qβ-MUC1 conjugates to powerfully induce both antibody and cytotoxic T cell immunity targeting tumor cells bode well for future translation of the constructs as anticancer vaccines.
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746.
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747.
  • Yin, ZH, et al. (författare)
  • Isolation of mouse hepatocytes for transplantation: a comparison between antegrade and retrograde liver perfusion
  • 2007
  • Ingår i: Cell transplantation. - : SAGE Publications. - 0963-6897 .- 1555-3892. ; 16:8, s. 859-865
  • Tidskriftsartikel (refereegranskat)abstract
    • We compared antegrade with retrograde liver perfusion when isolating mouse hepatocytes for hepatocyte transplantation. Male mouse hepatocytes were isolated by different perfusion methods and transplanted into the spleen of congeneic female mice. Retrograde perfusion yielded a larger number of cells (4.90 × 107) than antegrade (4.09 × 107, p < 0.05), but hepatocytes obtained by antegrade perfusion gave higher engraftment efficiency (p < 0.05). More of the transplanted hepatocytes could be recovered from recipient liver with antegrade perfusion than with retrograde perfusion (p < 0.05). Our results indicate that hepatocytes isolated by antegrade perfusion gave a higher engraftment efficiency.
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748.
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749.
  • Zaidi, Syed H., et al. (författare)
  • Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival
  • 2020
  • Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 11:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Colorectal cancer (CRC) is a biologically heterogeneous disease. To characterize its mutational profile, we conduct targeted sequencing of 205 genes for 2,105 CRC cases with survival data. Our data shows several findings in addition to enhancing the existing knowledge of CRC. We identify PRKCI, SPZ1, MUTYH, MAP2K4, FETUB, and TGFBR2 as additional genes significantly mutated in CRC. We find that among hypermutated tumors, an increased mutation burden is associated with improved CRC-specific survival (HR=0.42, 95% CI: 0.21-0.82). Mutations in TP53 are associated with poorer CRC-specific survival, which is most pronounced in cases carrying TP53 mutations with predicted 0% transcriptional activity (HR=1.53, 95% CI: 1.21-1.94). Furthermore, we observe differences in mutational frequency of several genes and pathways by tumor location, stage, and sex. Overall, this large study provides deep insights into somatic mutations in CRC, and their potential relationships with survival and tumor features. Large scale sequencing study is of paramount importance to unravel the heterogeneity of colorectal cancer. Here, the authors sequenced 205 cancer genes in more than 2000 tumours and identified additional mutated driver genes, determined that mutational burden and specific mutations in TP53 are associated with survival odds.
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750.
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