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Numrering	Referens	Omslagsbild	Hitta
41.	Clark, DW, et al. (författare) Associations of autozygosity with a broad range of human phenotypes 2019 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4957- Tidskriftsartikel (refereegranskat)abstract In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding.
42.	Clements, MS, et al. (författare) Estimating prevalence of distant metastatic breast cancer: a means of filling a data gap 2012 Ingår i: Cancer causes & control : CCC. - : Springer Science and Business Media LLC. - 1573-7225 .- 0957-5243. ; 23:10, s. 1625-1634 Tidskriftsartikel (refereegranskat)
43.	Davis, L, et al. (författare) CHARACTERIZING AN INVERSE AXIS BETWEEN ORTHOGONAL SOURCES OF GENETIC RISK 2017 Ingår i: EUROPEAN NEUROPSYCHOPHARMACOLOGY. - 0924-977X. ; 27, s. S130-S131 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
44.	Davis, LK, et al. (författare) Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture 2013 Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 9:10, s. e1003864- Tidskriftsartikel (refereegranskat)
45.	de Las Fuentes, L, et al. (författare) Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci 2023 Ingår i: Frontiers in genetics. - : Frontiers Media S.A.. - 1664-8021. ; 14, s. 1235337- Tidskriftsartikel (refereegranskat)
46.	de las Fuentes, L, et al. (författare) Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci 2023 Ingår i: Frontiers in genetics. - : Frontiers Media S.A.. - 1664-8021. ; 14, s. 1235337- Tidskriftsartikel (refereegranskat)
47.	Deshpande, A, et al. (författare) Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 2020 Ingår i: The Lancet. Global health. - 2214-109X. ; 8:9, s. E1162-E1185 Tidskriftsartikel (refereegranskat)
48.	Dorison, CA, et al. (författare) In COVID-19 Health Messaging, Loss Framing Increases Anxiety with Little-to-No Concomitant Benefits: Experimental Evidence from 84 Countries 2022 Ingår i: Affective science. - : Springer Science and Business Media LLC. - 2662-205X .- 2662-2041. ; 3:3, s. 577-602 Tidskriftsartikel (refereegranskat)
49.	Dork, T, et al. (författare) Two truncating variants in FANCC and breast cancer risk 2019 Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1, s. 12524- Tidskriftsartikel (refereegranskat)abstract Fanconi anemia (FA) is a genetically heterogeneous disorder with 22 disease-causing genes reported to date. In some FA genes, monoallelic mutations have been found to be associated with breast cancer risk, while the risk associations of others remain unknown. The gene for FA type C, FANCC, has been proposed as a breast cancer susceptibility gene based on epidemiological and sequencing studies. We used the Oncoarray project to genotype two truncating FANCC variants (p.R185X and p.R548X) in 64,760 breast cancer cases and 49,793 controls of European descent. FANCC mutations were observed in 25 cases (14 with p.R185X, 11 with p.R548X) and 26 controls (18 with p.R185X, 8 with p.R548X). There was no evidence of an association with the risk of breast cancer, neither overall (odds ratio 0.77, 95%CI 0.44–1.33, p = 0.4) nor by histology, hormone receptor status, age or family history. We conclude that the breast cancer risk association of these two FANCC variants, if any, is much smaller than for BRCA1, BRCA2 or PALB2 mutations. If this applies to all truncating variants in FANCC it would suggest there are differences between FA genes in their roles on breast cancer risk and demonstrates the merit of large consortia for clarifying risk associations of rare variants.
50.	Feigin, VL, et al. (författare) Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015 2017 Ingår i: The Lancet. Neurology. - 1474-4465 .- 1474-4422. ; 16:11, s. 877-897 Tidskriftsartikel (refereegranskat)

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