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Sökning: WFRF:(Zhang Li)

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2761.
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2762.
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2763.
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2764.
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2765.
  • Zhou, J., et al. (författare)
  • Self-excited piezoelectric microcantilever for gas detection
  • 2003
  • Ingår i: Microelectronic Engineering. - 0167-9317 .- 1873-5568. ; 69:1, s. 37-46
  • Tidskriftsartikel (refereegranskat)abstract
    • Design, fabrication and results from theoretical and experimental studies on the self-excited piezoelectric microcantilever are presented in this paper. Theoretical studies have been carried out to design the microcantilever and have been extended to harmonic analysis using the finite element technique. Silicon microfabrication has been successfully completed to create microcantilever devices. Experimental studies have been performed to obtain the resonance frequencies. Applied as a mass-sensitive sensor, the microcantilever has a sensitivity of - 0.0024%/ppm and a minimum mass loading of 3.5 x 10(-9) g with the help of a zeolite sensitive layer to freon.
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2766.
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2767.
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2768.
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2769.
  • Zhou, QJ, et al. (författare)
  • Seroprevalence of Cytomegalovirus and Associated Factors Among Preconception Women: A Cross-Sectional Nationwide Study in China
  • 2021
  • Ingår i: Frontiers in public health. - : Frontiers Media SA. - 2296-2565. ; 9, s. 631411-
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Cytomegalovirus seroconversion during pregnancy is common and has a substantial risk of congenital infection with longterm sequale. Screening during pregnancy or vaccination have not been shown to be effective for eliminating congenital infections. Preconception screening policy has not been evaluated adequately in a large scale. This nationwide study aimed to investigate epidemiological features of cytomegalovirus seropositivity and its geographic variation among Chinese women planning a pregnancy to gather epidemiological evidence as an essential for developing novel prevention strategies.Method: This cross-sectional sero-epidemiological survey enrolled women intending to become pregnant within 6 months in mainland China during 2010–2012. The primary outcomes in this study were cytomegalovirus Immunoglobulin G and M seropositivity. Secondary outcomes were the associations between Immunoglobulin G and Immunoglobulin M, with socio-demographic characteristics, including age, occupation, education level, place of residence, and ethnicity. The overall seropositivity and regional disparity was analyzed on the individual and regional level, respectively.Results: This study included data from 1,564,649 women from 31 provinces in mainland China. Among participants, 38.6% (n = 603,511) were cytomegalovirus immunoglobulin G+, 0.4% (n = 6,747) were immunoglobulin M+, and 0.2% (n = 2,879) were immunoglobulin M+ and immunoglobulin G+. On individual level, participant's age, ethnicity, and residing region were significantly associated with IgG+, IgM+, and IgM+IgG+ (P < 0.001), while occupation, education level, and place of residence were not statistically significant (P > 0.05). On regional level, cytomegalovirus immunoglobulin G and immunoglobulin M seropositivity was highest in the eastern region (49.5 and 0.5%, respectively), and lowest in the western region (26.9 and 0.4%, respectively). This geographic variation was also noted at the provincial level, characterized by higher provincial immunoglobulin M+ and immunoglobulin G+ rates associated with higher immunoglobulin G seropositivity. In the subgroup analysis of immunoglobulin G seropositivity, areas of higher immunoglobulin G positivity had a higher rate of immunoglobulin M+, indicating an expected increased risk of reinfection and primary infection.Conclusions: A substantial proportion of women (>60%) were susceptible to cytomegalovirus in preconception period in China, and immunoglobulin G seropositivity was seen at a low-medium level with substantial geographic variation. Integration of cytomegalovirus antibody testing in preconception screening program based on regional immunoglobulin G seropositivity, should be considered to promote strategies directed toward preventing sero-conversion during pregnancy to reduce the risk of this congenital infection.
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2770.
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