| 21. |
- Han, Xue, et al.
(författare)
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Empirical analysis for Distributed Energy Resources' impact on future distribution network
- 2012
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Ingår i: Energy Conference and Exhibition (ENERGYCON), 2012 IEEE International. - : IEEE. - 9781467314541 ; , s. 731-737
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Konferensbidrag (refereegranskat)abstract
- There has been a large body of statements claiming that the large scale deployment of Distributed Energy Resources (DERs) will eventually reshape the future distribution grid operation in various ways. Thus, it is interesting to introduce a platform to interpret to what extent the power system operation will be alternated. In this paper, quantitative results in terms of how the future distribution grid will be changed by the deployment of distributed generation, active demand and electric vehicles, are presented. The analysis is based on the conditions for both a radial and a meshed distribution network. The input parameters are based on the current and envisioned DER deployment scenarios proposed for Sweden.
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| 22. |
- Han, Xue, et al.
(författare)
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Modelling Framework and the Quantitative Analysis of Distributed Energy Resources in Future Distribution Networks
- 2013
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Ingår i: International Journal of Emerging Electric Power Systems. - : De Gruyter. - 2194-5756 .- 1553-779X. ; 14:5, s. 421-431
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Tidskriftsartikel (refereegranskat)abstract
- There has been a large body of statements claiming that the large-scale deployment of Distributed Energy Resources (DERs) could eventually reshape the future distribution grid operation in numerous ways. Thus, it is necessary to introduce a framework to measure to what extent the power system operation will be changed by various parameters of DERs. This article proposed a modelling framework for an overview analysis on the correlation between DERs. Furthermore, to validate the framework, the authors described the reference models of different categories of DERs with their unique characteristics, comprising distributed generation, active demand and electric vehicles. Subsequently, quantitative analysis was made on the basis of the current and envisioned DER deployment scenarios proposed for Sweden. Simulations are performed in two typical distribution network models for four seasons. The simulation results show that in general the DER deployment brings in the possibilities to reduce the power losses and voltage drops by compensating power from the local generation and optimizing the local load profiles.
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| 23. |
- He, Shu, et al.
(författare)
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A global assay of haemostasis which uses recombinant tissue factor and tissue-type plasminogen activator to measure the rate of fibrin formation and fibrin degradation in plasma
- 2007
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Ingår i: Thrombosis and Haemostasis. - 0340-6245 .- 2567-689X. ; 98:4, s. 871-882
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Tidskriftsartikel (refereegranskat)abstract
- The global assay of Overall Haemostasis Potential we previously described has been refined. The coagulation cascade in platelet-poor plasma is triggered by adding a minimal dose of recombinant tissue factor together with purified phospholipids and calcium; fibrinolysis is initiated by adding recombinant tissue type-plasminogen activator in a concentration similar to what can be obtained during thrombolysis. Numerical differentials of optical densities reflecting rates of fibrin formation and degradation are calculated by a new software, and the Coagulation Profile (Cp) and the Fibrinolysis Profile (Fp) are determined. The combined effect of these counteractive systems is expressed as a ratio of Cp to Fp, called the Overall Haemostasis Index. Commercially available coagulant-deficient patient plasma samples and plasma with various amounts of added PAI-1 are examined; changes of fibrin turbidity demonstrate that this assay can determine Cp and Fp in a physiologically relevant way. Increased Cp and decreased Fp in prothrombotic patients, as well as expected effects of heparin or a thrombin inhibitor on Cp and Fp, suggest that our method can detect hypercoagulability and assist in monitoring antithrombotic treatment. Ongoing studies will show whether this simple assay can be of value in clinical routine.
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| 24. |
- Honeth, Nicholas, et al.
(författare)
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Decentralized topology inference of electrical distribution networks
- 2012
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Ingår i: 2012 IEEE PES Innovative Smart Grid Technologies, ISGT 2012. - : IEEE. - 9781457721588
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Konferensbidrag (refereegranskat)abstract
- Power system operation and control relies heavily on models for decision making. Topology is a critical part of producing these models and maintaining up-to-date topologies of electrical distribution networks is a resource consuming and challenging task. This paper proposes a methodology and system architecture for inference of electrical topology using process and model data from IEC 61850 compliant substation automation devices. A system of autonomous intelligent agents communicating via an overlay network is proposed where agents are capable of communicating on the IEC 61850 station bus. An algorithm for topology inference using structured exchange and comparison of process and model information is developed. The capabilities of structured information exchange and interfacing of substation automation devices enables plug-and-play operation of the topology inference requiring minimal prior knowledge of electrical network structure. Decentralized topology inference forms the basis for future work in operation and management of active distribution networks.
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| 25. |
- König, Johan, et al.
(författare)
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Mapping the Substation Configuration Language of IEC 61850 to ArchiMate
- 2010
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Ingår i: Proceedings - IEEE International Enterprise Distributed Object Computing Workshop, EDOC. - : IEEE. - 9780769541648 ; , s. 60-68
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Konferensbidrag (refereegranskat)abstract
- This paper presents a mapping between the Enterprise Architecture framework ArchiMate and the Substation Configuration Language (SCL) of IEC 61850. Enterprise Architecture (EA) is a discipline for managing an enterprise's information system portfolio in relation to the supported business. Metamodels, descriptive models on how to model and one of the core components of EA, can assist stakeholders in many ways, for example in decision-making. Moreover, the power industry is a domain with an augmented reliance on the support of information systems. IEC 61850 is a standard for the design of Substation Automation (SA) systems and provides a vendor independent framework for interoperability by defining communication networks and functions. The SCL is a descriptive language in IEC 61850 on the configuration of substation Intelligent Electronic Devices (IED) which describes the structure together with physical components and their relating functions. By using SCL, which models the architecture of SA systems, and mapping it to ArchiMate, stakeholders are assisted in understanding their SA system and its architecture. The mapping is intended to support the integration of SA systems applying IEC 61850 into the enterprise architecture. The mapping is demonstrated with an example applying the mapping to a SA configuration based on SCL.
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| 26. |
- Liu, Ching-Ti, et al.
(författare)
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Assessment of gene-by-sex interaction effect on bone mineral density
- 2012
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Ingår i: Journal of Bone and Mineral Research. - : Wiley. - 1523-4681 .- 0884-0431. ; 27:10, s. 2051-2064
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Tidskriftsartikel (refereegranskat)abstract
- Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects by sex, we examined gene-by-sex autosomal interactions genome-wide, and performed expression quantitative trait loci (eQTL) analysis and bioinformatics network analysis. We conducted an autosomal genome-wide meta-analysis of gene-by-sex interaction on lumbar spine (LS) and femoral neck (FN) BMD in 25,353 individuals from 8 cohorts. In a second stage, we followed up the 12 top single-nucleotide polymorphisms (SNPs; p?
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| 27. |
- Moayyeri, Alireza, et al.
(författare)
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Genetic determinants of heel bone properties : genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
- 2014
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Ingår i: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:11, s. 3054-3068
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Tidskriftsartikel (refereegranskat)abstract
- Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by X-ray (DXA), may be convenient alternatives for evaluating osteoporosis and fracture risk. We performed a meta-analysis of genome-wide association (GWA) studies to assess the genetic determinants of heel broadband ultrasound attenuation (BUA; n = 14 260), velocity of sound (VOS; n = 15 514) and BMD (n = 4566) in 13 discovery cohorts. Independent replication involved seven cohorts with GWA data (in silico n = 11 452) and new genotyping in 15 cohorts (de novo n = 24 902). In combined random effects, meta-analysis of the discovery and replication cohorts, nine single nucleotide polymorphisms (SNPs) had genome-wide significant (P < 5 x 10(-8)) associations with heel bone properties. Alongside SNPs within or near previously identified osteoporosis susceptibility genes including ESR1 (6q25.1: rs4869739, rs3020331, rs2982552), SPTBN1 (2p16.2: rs11898505), RSPO3 (6q22.33: rs7741021), WNT16 (7q31.31: rs2908007), DKK1 (10q21.1: rs7902708) and GPATCH1 (19q13.11: rs10416265), we identified a new locus on chromosome 11q14.2 (rs597319 close to TMEM135, a gene recently linked to osteoblastogenesis and longevity) significantly associated with both BUA and VOS (P < 8.23 x 10(-14)). In meta-analyses involving 25 cohorts with up to 14 985 fracture cases, six of 10 SNPs associated with heel bone properties at P < 5 x 10(-6) also had the expected direction of association with any fracture (P < 0.05), including three SNPs with P < 0.005: 6q22.33 (rs7741021), 7q31.31 (rs2908007) and 10q21.1 (rs7902708). In conclusion, this GWA study reveals the effect of several genes common to central DXA-derived BMD and heel ultrasound/DXA measures and points to a new genetic locus with potential implications for better understanding of osteoporosis pathophysiology.
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| 28. |
- Nordström, Lars, et al.
(författare)
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A Multi-Disciplinary Course Portfolio on Computer Applications in Power Systems
- 2014
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Ingår i: IEEE Transactions on Power Systems. - 0885-8950 .- 1558-0679. ; 29:4, s. 1919-1927
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Tidskriftsartikel (refereegranskat)abstract
- As a response to the new requirements posed by the shift towards Smartgrids, there have been many initiatives worldwide to develop and update power engineering education curricula. This paper reports efforts to develop courses with the purpose to cross the gap between the disciplines of power engineering and information communication technology at KTH-the Royal Institute of Technology in Sweden. The course portfolio is engineered to complement several master programs offered by the university, and the intended audience are students and practitioners both with and without the power engineering background. This paper primarily focuses on details of a keystone course, Computer Applications in Power Systems, and its connection with the other courses in the portfolio. To prove the popularity and relevance of the reported course portfolio, increasingly positive feedback from students, recognition from industry partners, and accomplishments in terms of meeting several strategic goals in education set by the IEEE Power & Energy Society are also reported by this paper.
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| 29. |
- Nordström, Lars, et al.
(författare)
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Information and communication system architectures for wide-area monitoring and control applications
- 2011
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Konferensbidrag (refereegranskat)abstract
- This paper presents a review of work performed in the field of communication systems requirements for wide area monitoring and control applications. This includes studies performed both in the context of NASPI, the North American Syncrophasor Initiative, as well as other studies in the US and Europe. Presently a relatively large body of work has been done regarding the requirements on the communication infrastructure. Among the work included, are surveys among Transmission System Operators on the foreseen communication requirements, as well as other theoretical studies on acceptable delays and other performance characteristics, such as data loss, that Wide Area Control applications put on the Information and Communication System. Much of the above referenced work still needs verification either though experimental work or through simulations. It is especially important to simulate large scale communication infrastructures that consider background traffic under different operational conditions in the power system, such as under disturbances. The paper is concluded with some remarks on future direction of work within the field.
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| 30. |
- Oei, Ling, et al.
(författare)
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A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus
- 2014
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Ingår i: Journal of Medical Genetics. - : BMJ Publishing Group. - 0022-2593 .- 1468-6244. ; 51:2, s. 122-131
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Osteoporosis is a systemic skeletal disease characterised by reduced bone mineral density and increased susceptibility to fracture; these traits are highly heritable. Both common and rare copy number variants (CNVs) potentially affect the function of genes and may influence disease risk.AIM: To identify CNVs associated with osteoporotic bone fracture risk.METHOD: We performed a genome-wide CNV association study in 5178 individuals from a prospective cohort in the Netherlands, including 809 osteoporotic fracture cases, and performed in silico lookups and de novo genotyping to replicate in several independent studies.RESULTS: A rare (population prevalence 0.14%, 95% CI 0.03% to 0.24%) 210 kb deletion located on chromosome 6p25.1 was associated with the risk of fracture (OR 32.58, 95% CI 3.95 to 1488.89; p=8.69×10(-5)). We performed an in silico meta-analysis in four studies with CNV microarray data and the association with fracture risk was replicated (OR 3.11, 95% CI 1.01 to 8.22; p=0.02). The prevalence of this deletion showed geographic diversity, being absent in additional samples from Australia, Canada, Poland, Iceland, Denmark, and Sweden, but present in the Netherlands (0.34%), Spain (0.33%), USA (0.23%), England (0.15%), Scotland (0.10%), and Ireland (0.06%), with insufficient evidence for association with fracture risk.CONCLUSIONS: These results suggest that deletions in the 6p25.1 locus may predispose to higher risk of fracture in a subset of populations of European origin; larger and geographically restricted studies will be needed to confirm this regional association. This is a first step towards the evaluation of the role of rare CNVs in osteoporosis.
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