| 21. |
- Päären, Aivar, et al.
(författare)
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Hypomania spectrum disorders from adolescence to adulthood : A 15-year follow-up of a community sample
- 2013
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Ingår i: Journal of Affective Disorders. - : Elsevier BV. - 0165-0327 .- 1573-2517. ; 145:2, s. 190-199
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Tidskriftsartikel (refereegranskat)abstract
- Background: There is a lack of scientific knowledge about the broader spectrum of hypomania in adolescence and the course over time. To investigate this, we used longitudinal data spanning from adolescence to age 31 years.Method: A community sample of adolescents (N=2300) was screened for depressive symptoms. Adolescents (16-17 years) with a positive screening and matched controls were interviewed with a structured diagnostic interview. A blinded follow-up assessment was conducted 15 years later, with a structured diagnostic interview covering the age span 19-31 years. Questions about treatment and family history were included.Results: Ninety adolescents (16-17 years) with a lifetime hypomania spectrum episode (3.9% of the total sample) were identified: 40 with fullsyndromal, 18 with brief-episode (<4 day), and 32 with subsyndromal (1-2 main symptoms and 1-2 additional symptoms) hypomania. The hypomania symptoms reported by the fullsyndromal and the brief-episode groups were similar, whereas the subsyndromal group per definition reported fewer symptoms. Of the 90 adolescents with a hypomania spectrum episode, 64 (71%) participated in the follow-up interview. Mania in adulthood was reported by 2 (3%), hypomania by an additional 4 (6%), and major depression by 38 (59%). Incidence of mood episodes in adulthood did not differ between the subgroups of hypomania spectrum.Limitations: 29% of the participants with hypomania spectrum were lost to follow-up.Conclusion: The results indicate that only a small proportion of adolescents with hypomania spectrum episodes continue to have (hypo)mania in adulthood. Thus, maintenance or prophylactic treatment does not seem warranted for this group.
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| 22. |
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| 23. |
- Ramklint, Mia, et al.
(författare)
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Child and adolescent psychiatric disorders predicting adult personality disorder : A follow-up study
- 2003
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Ingår i: Nordic Journal of Psychiatry. - 0803-9488 .- 1502-4725. ; 57:1, s. 23-28
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was to examine associations between childhood and adolescent psychiatric disorders and adult personality disorders in a group of former child psychiatric inpatients. One hundred and fifty-eight former inpatients with a mean age of 30.5 +/- 7.1 years at investigation had their childhood and adolescentAxis I disorders, obtained from their medical records, coded into DSM-IV diagnoses.Personality disorders in adulthood were assessed by means of the DSM-IV and ICD-10 Personality Questionnaire (DIP-Q). The predictive effects of child and adolescentAxis I disorders on adult personality disorders were examined with logistic regression analyses. The odds of adult schizoid, avoidant, dependent, borderline and schizotypalpersonality disorders increased by almost 10, five, four, three and three times, respectively, given a prior major depressive disorder. Those effects were independent of age, sex and other Axis I disorders. In addition, the odds of adult narcissistic and antisocial personality disorders increased by more than six and five times, respectively, given a prior disruptive disorder, and the odds of adult borderline, schizotypal, avoidant and paranoid personality disorders increased between two and three times given a prior substance-related disorder. The results illustrate an association between mental disorders in childhood and adolescence and adultpersonality disorders. Identification and successful treatment of childhood psychiatricdisorders may help to reduce the risk for subsequent development of an adultpersonality disorder.
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| 24. |
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| 25. |
- Ramklint, Mia, et al.
(författare)
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Conduct disorder and personality in a forensic psychiatric population
- 2001
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Ingår i: European Journal of Psychiatry. - 0213-6163 .- 2340-4469. ; 15:4, s. 245-254
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Tidskriftsartikel (refereegranskat)abstract
- The present study examined 61 men at forensic psychiatric investigation. We compared subjects with or without an assessed previous conduct disorder (CD versus non CD). The CD group showed more DSM-HI-R personality disorders, exhibited more repeated violent criminality and more mixed drug abuse. The CD group differed from the non CD group according to specific personality traits assessed by the Karolinska Scales of Personality (KSP) showing lower scores on the Social desirability and Socialization scale, and higher scores on the Impulsiveness, Monotony avoidance, Verbal aggression, Iritability and Suspicion scales. The CD group had higher psychopathy scores assessed by the Psychopathy Checklist-Revised (PCL-R). The results are in accordance with previous findings in juvenile conduct disordered men. They indicate that personality traits are detectable early in life and stable over time influencing behaviours such as criminality and drug abuse.
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| 26. |
- Ramklint, Mia, et al.
(författare)
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Personality disorders in former child psychiatric patients
- 2002
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Ingår i: European Child and Adolescent Psychiatry. - : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 11, s. 289-295
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Tidskriftsartikel (refereegranskat)abstract
- The present case-control study was undertaken in order to investigate the long-term outcome with respect to personality disorder (PD) symptomatology in former childpsychiatric in-patients as compared to matched controls from the general population. Altogether 359 former patients and 359 controls were invited to participate in the study. Of these, 164 (46%) former patients and 193 (54%) controls approved participation. From these, 137 age and sex-matched pairs with a mean age of 30.7 (SD = 6.8) years were constructed. Adult PD symptomatology was assessed by means of the DSM-IV and ICD-10 PersonalityQuestionnaire (DIP-Q). There were 52 former patients (38%) and 15 controls (10.9%) who fulfilled criteria for at least one DSM-IV self-reported PD. There was a significantly higher prevalence for all specific self-reported PDs in former patients compared to controls. The mean number of disorders was 1.7 (SD = 2.6) in former patients and 0.3 (SD = 0.8) incontrols. Moreover, former patients fulfilled more PD criteria than controls (23 vs. 11; median numbers). The former patients had significantly lower global functioning and more psychosocial problems than the controls. These problems were related to personalitypathology. The results of this study indicate that child psychiatric morbidity seems to increase the risk for adult PD symptomatology. However, the results may be biased by the low participation rate.
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| 27. |
- Ramklint, Mia, et al.
(författare)
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Triiodothyronine (T3) related to adolescent conduct disorder in a forensic psychiatric population
- 2000
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Ingår i: European Journal of Psychiatry. - 0213-6163 .- 2340-4469. ; 14:1, s. 33-41
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Tidskriftsartikel (refereegranskat)abstract
- he present study evaluates the relatioships between the thyroid hormones, triiodothyronine (T3) and thyroxine (FT4), in adult life and a history of conduct disorder in 61 men from a forensic psychiatric population. The study population was divided into four groups based on the presence or not of an assessed conduct disorder, as well as a previous child psychiatric contact. The highest T3 values were found in patients with both a previous conduct disorder and a previous child psychiatric contact. There was a positive relationship between conduct disorder and serum levels of FT4. These results may indicate that T3 is a biological marker of aggressive behaviour in children.
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| 28. |
- Ssegonja, Richard, et al.
(författare)
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Association of adolescent depression with subsequent prescriptions of anti-infectives and anti-inflammatories in adulthood : A longitudinal cohort study
- 2022
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Ingår i: Psychiatry Research. - : Elsevier. - 0165-1781 .- 1872-7123. ; 317
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Tidskriftsartikel (refereegranskat)abstract
- New insights into how depression is linked to physical health throughout the lifespan could potentially inform clinical decision making. The aim of this study was to explore the association of adolescent depression with subsequent prescriptions of anti-infectives and anti-inflammatories in adulthood. The study was based on the Uppsala Longitudinal Adolescent Depression Study (ULADS), a Swedish prospective cohort study initiated in 1991. Depressed (n = 321) and non-depressed (n = 218) adolescents were followed prospectively using patient registries. The associations of adolescent depression (age 16-17 years) with subsequent prescription of anti-infectives and anti-inflammatories (age 30-40 years), were analysed using generalized linear models. Sub -analyses explored the impact of diagnostic characteristics in adolescence and reception of anti-depressants prescriptions in adulthood. The results suggest that females with persistent depressive disorder in adolescence have a higher rate of future prescriptions than non-depressed peers, with adjusted incidence rate ratio of 1.42 (1.06 to 1.92) for anti-infectives and 1.72 (1.10 to 2.70) for anti-inflammatories. These associations were mainly driven by those who were also prescribed antidepressants during the same period. Associations were less robust for females with episodic or subsyndromal depression in adolescence and for males. These findings emphasize the importance of integrated mental health services at the primary healthcare level.
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| 29. |
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