| 381. |
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| 382. |
- Rubboli, Andrea, et al.
(författare)
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Esperienza iniziale sulluso di abciximab nel trattamento di salvataggio della trombosi coronarica acuta nel Laboratorio di Emodinamica [Initial experience with the use of abciximab in the salvage treatment of acute coronary thrombosis in the Hemodynamics Laboratory]
- 1998
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Ingår i: Cardiologia (Rome, Italy). - 0393-1978. ; 43:11, s. 1221-1229
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The optimal treatment of acute thrombotic complications in the Catheterization Laboratory has not been defined yet, due to the limited efficacy shown by various pharmacological regimens, even when associated to coronary angioplasty (PTCA). The aim of our study was therefore to evaluate the effects of abciximab (ReoPro), a new potent inhibitor of the platelet glycoprotein IIb/IIIa, when administered as a rescue treatment for acute thrombotic coronary occlusion during diagnostic or interventional procedures. Sixteen patients (12 males, 4 females, mean age 59.3 +/- 9.2 years, range 43-77 years), with unstable angina and consecutively treated with abciximab due to clinical instability attributable to coronary thrombosis angiographically proven during PTCA (9 cases) or diagnostic angiography (7 cases), were identified. The individual angiographic films and medical records were then reviewed in order to evaluate the effects of treatment on coronary flow, thrombus size and occurrence of in-hospital adverse events: death, non-fatal acute myocardial infarction (AMI), need for urgent myocardial revascularization and hemorrhage. The administration of abciximab, in association with PTCA (associated in turn with stent implantation in 8 cases), induced a significant increase of coronary TIMI flow grade (0.3 +/- 0.6 vs 2.4 +/- 0.9; p less than 0.05) and a significant decrease of thrombus score (size) 2.4 +/- 0.9 vs 1.3 +/- 0.6; p less than 0.01). No deaths nor need for urgent myocardial revascularization were observed; in 31% of cases (5 patients) evolution towards AMI occurred, while however 94% of cases (15 patients) had a coronary occlusion before treatment. No major hemorrhagic complications were observed, while in 12% of cases (2 patients) a groin hematoma associated with moderate hemoglobin drop, developed. In conclusion, the administration of abciximab, associated with the common rescue interventional procedures, in patients with acute thrombotic coronary occlusion in the Catheterization Laboratory, appears to be effective in restoring adequate coronary flow and reducing the thrombus size (limiting therefore the evolution towards AMI), and safe, not having been associated with significant hemorrhagic complications.
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| 383. |
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| 384. |
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| 385. |
- Sabatini, Serena, 1974
(författare)
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Mobilità e società nella Scandinavia meridionale dell’età del bronzo
- 2023
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Ingår i: Studi di Protostoria in memoria di Renato Peroni edited by P. Miranda. In: Universitätsforschungen zur prähistorischen Archäologie 394. - Bonn : Verlag Dr. Rudolf Habelt GMBH. - 9783774944176 ; , s. 327-340
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this contribution is, in the first place, to discuss issues of mobility in Bronze Age societies from Southern Scandinavia. Both trade and exchange of raw material and goods as well as individual and group mobility will be addressed. A number of studies from Scandinavia have shown that a significant amount of materials, such as metal, glass and textiles, reached northern Europe from distant sources during the Bronze Age. The evidence suggests that specialized centres of production and various networks, embracing the whole continent, were at work at the same time and powered a complex pattern of exchanges of raw supplies and/or finished products. While advances in ancient DNA and population genomics studies made it possible to prove the existence of significant prehistoric migrations, the study of individual mobility has also acquired completely new dimensions. Biomolecular and biogeochemical analyses on the female depositions found at Egtved and Skrydstrup, in present day Denmark, suggest for instance that some young Bronze Age women travelled conspicuous distances and died in areas where they did not spend their childhood. From an archaeological point of view the characteristics of their graves being – we could say – typical of the local Bronze Age, had not previously given any hint as to the possibility of such complex personal histories. Finally, it is argued that a number of studies initially focusing on the Scandinavian Bronze Age have now paved the way for a new understanding of the broader European context. The paper concludes with very brief reflections on the problems and challenges that the archaeosciences presents to the scientific community. It is argued for the necessity to elaborate renovated methodological and theoretical approaches for the interpretation of the new scientific evidence.
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| 386. |
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| 387. |
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| 388. |
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| 389. |
- Santoro, Stefano, et al.
(författare)
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Introduzione
- 2020
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Ingår i: Clio nei socialismi reali. - Milan : Edizioni Unicopli. - 9788840021096 ; , s. 7-17
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Per oltre quarant’anni, la scrittura della storia nei paesi dell’Europa orientaleè stata fortemente condizionata dagli imperativi ideologici e propagandisticidei regimi comunisti. La storia, più di ogni altra disciplina umanistica, offrivagiustifi cazioni, e quindi legittimità, al potere. Indagare il rapporto tra storia epotere in questo ambito signifi ca tanto addentrarsi nella storia dei socialismireali e dei loro obiettivi – strategie, tattiche, tra rotture con il passato e continuità– quanto approfondire il rapporto che storici ed istituzioni di ricercaintrattenevano con la politica.I saggi presentati in questo volume si concentrano su alcuni aspetti cruciali delrapporto tra Clio e dittature comuniste, dal signifi cato del mestiere di storicoall’interno di realtà che spingevano a cercare accomodamenti e compromessicon il regime – pena la marginalizzazione o la persecuzione –, all’analisidell’interazione delle storiografi e e della loro evoluzione in relazione ai rispettivicontesti istituzionali, all’uso pubblico della storia e dei miti storici da partedei regimi comunisti.
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| 390. |
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