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Sökning: db:Swepub > Nilsson Peter

  • Resultat 1131-1140 av 2005
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  • Nilsson, Peter (författare)
  • Butler's stone and ultimate psychological hedonism
  • 2013
  • Ingår i: Philosophia. - : Springer Science and Business Media LLC. - 0048-3893 .- 1574-9274. ; 41:2, s. 545-553
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper discusses psychological hedonism with special reference to the writings of Bishop Butler, and Elliott Sober and David Sloan Wilson. Contrary to philosophical orthodoxy, Sober and Wilson have argued that Butler failed to refute psychological hedonism. In this paper it is argued: (1) that there is a difference between reductive and ultimate psychological hedonism; (2) that Butler failed to refute ultimate psychological hedonism, but that he succeeded in refuting reductive psychological hedonism; and, finally and more importantly, (3) that Butler's criticism of reductive hedonism can be used as a stepping-stone in another argument showing the implausibility of ultimate psychological hedonism as well.
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1135.
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1137.
  • Nilsson, Peter (författare)
  • Cardiovascular risk in the metabolic syndrome: fact or fiction?
  • 2007
  • Ingår i: Current Cardiology Reports. - 1534-3170. ; 9:6, s. 479-485
  • Tidskriftsartikel (refereegranskat)abstract
    • In population-based studies, a cluster of cardiovascular risk factors comprising the metabolic syndrome (MetS) has been documented as predictive of cardiovascular disease events and type 2 diabetes. Currently, there are several proposed definitions of the MetS, although data support some advantages of using the 2005 National Cholesterol Education Program Adult Treatment Panel III definition, which is considered superior to most others, including the one from the 2005 International Diabetes Federation study. One controversial issue is that some of the conventional cardiovascular risk factors included in the MetS cluster appear to be equally predictive of cardiovascular outcomes as the syndrome itself (eg, the influence of smoking habits). Further observational and intervention studies are needed to explore this issue and target the core problem of the syndrome, which is proposed to be insulin resistance. Useful therapies for the metabolic syndrome include lifestyle modification and drugs that lower conventional cardiovascular risk factors, such as metformin, the "glitazones," and evidence-based drugs.
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1138.
  • Nilsson, Peter, et al. (författare)
  • Chip and solution detection of DNA hybridization using a luminescent zwitterionic polythiophene derivative
  • 2003
  • Ingår i: Nature Materials. - : Springer Science and Business Media LLC. - 1476-1122 .- 1476-4660. ; 2:6, s. 419-424
  • Tidskriftsartikel (refereegranskat)abstract
    • Electronic polymers in aqueous media may offer bioelectronic detection of biospecific interactions. Here we report a fluorometric DNA hybridization detection method based on non-covalent coupling of DNA to a water-soluble zwitterionic polythiophene derivative. Introduction of a single-stranded oligonucleotide will induce a planar polymer and aggregation of the polymer chains, detected as a decrease of the intensity and a red-shift of the fluorescence. On addition of a complementary oligonucleotide, the intensity of the emitted light is increased and blue-shifted. The detection limit of this method is at present ~10−11 moles. The method is highly sequence specific, and a single-nucleotide mismatch can be detected within five minutes without using any denaturation steps. The interaction with DNA and the optical phenomena persists when the polymer is deposited and patterned on a surface. This offers a novel way to create DNA chips without using covalent attachment of the receptor or labelling of the analyte.
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1139.
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1140.
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