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  • Dagöö, Jesper, et al. (författare)
  • Cognitive behavior therapy versus interpersonal psychotherapy for social anxiety disorder delivered via smartphone and computer: : A randomized controlled trial
  • 2014
  • Ingår i: Journal of Anxiety Disorders. - Elsevier. - 0887-6185. ; 28:4, s. 410-417
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study, a previously evaluated guided Internet-based cognitive behavior therapy for social anxiety disorder (SAD) was adapted for mobile phone administration (mCBT). The treatment was compared with a guided self-help treatment based on interpersonal psychotherapy (mIPT). The treatment platform could be accessed through smartphones, tablet computers, and standard computers. A total of 52 participants were diagnosed with SAD and randomized to either mCBT (n = 27) or mIPT (n = 25). Measures were collected at pre-treatment, during the treatment, post-treatment and 3-month follow-up. On the primary outcome measure, the Liebowitz Social Anxiety Scale - self-rated, both groups showed statistically significant improvements. However, mCBT performed significantly better than mIPT (between group Cohens d = 0.64 in favor of mCBT). A larger proportion of the mCBT group was classified as responders at post-treatment (55.6% versus 8.0% in the mIPT group). We conclude that CBT for SAD can be delivered using modern information technology. IPT delivered as a guided self-help treatment may be less effective in this format.
  • Hulegardh, E., et al. (författare)
  • Outcome after HSCT in Philadelphia chromosome positive acute lymphoblastic leukemia in Sweden: : a population-based study
  • 2014
  • Ingår i: Medical Oncology. - Humana Press. - 1357-0560. ; 31:8, s. 66
  • Tidskriftsartikel (refereegranskat)abstract
    • Even in the tyrosine kinase inhibitor era, allogeneic hematopoietic stem cell transplantation (HSCT) is regarded as standard care for adult Philadelphia (Ph) positive acute lymphoblastic leukemia (ALL). In this retrospective national study, we have reviewed the outcome after HSCT in Sweden for adult Ph-positive ALL between 2000 and 2009. In total, 51 patients with median age 42 (range 20-66) years underwent HSCT. Mainly allogeneic HSCT was performed (24 related donor, 24 unrelated donor and one cord blood), and only two patients were treated with an autologous HSCT. The 5-year OS was 51 (37-64) %. The probabilities of morphological relapse and non-relapse mortality (NRM) at 5 years were 36 (23-49) and 18 (9-29) %, respectively. For the allogeneic transplanted, the 5-year OS was for patients less than40 years 70 (50-90) % and for patients greater than= 40 years 34 (16-52) %, p = 0.002. The 5-year probability of NRM was for patients less than40 years 10 (2-28) % compared to 25 (11-42) % for patients greater than= 40 years (p = 0.04). Patients with chronic graft-versus-host disease (GVHD) had a 5-year morphological relapse probability of 20 (6-40) % compared to 59 (35-77) % for patients without chronic GVHD (p = 0.03). Age greater than= 40 years and the absence of chronic GVHD were confirmed as independent negative prognostic factors for relapse and non-relapse mortality in a multivariate analysis although the impact of chronic GVHD was significant only in the older age cohort.
  • Olsson-Strömberg, Ulla, et al. (författare)
  • Successful mobilization of Ph-negative blood stem cells with intensive chemotherapy + G-CSF in patients with chronic myelogenous leukemia in first chronic phase
  • 2006
  • Ingår i: Leukemia and Lymphoma. - 1042-8194. ; 47:9, s. 1768-1773
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of the study was to investigate the feasibility of mobilizing Philadelphia chromosome negative (Ph-) blood stem cells (BSC) with intensive chemotherapy and lenograstim (G-CSF) in patients with CML in first chronic phase (CP1). During 1994-1999 12 centers included 37 patients <56 years. All patients received 6 months' IFN, stopping at median 36 (1-290) days prior to the mobilization chemotherapy. All received one cycle of daunorubicin 50 mg/m2 and 1 hour infusion on days 1-3, and cytarabine (ara-C) 200 mg/m2 24 hours' i.v. infusion on days 1-7 (DA) followed by G-CSF 526 microg s.c. once daily from day 8 after the start of chemotherapy. Leukaphereses were initiated when the number of CD 34+ cells was >5/microl blood. Patients mobilizing poorly could receive a 4-day cycle of chemotherapy with mitoxantrone 12 mg/m2/day and 1 hour i.v infusion, etoposide 100 mg/m2/day and 1 hour i.v. infusion and ara-C 1 g/m2/twice a day with 2 hours' i.v infusion (MEA) or a second DA, followed by G-CSF 526 microg s.c once daily from day 8 after the start of chemotherapy. Twenty-seven patients received one cycle of chemotherapy and G-CSF, whereas 10 were mobilized twice. Twenty-three patients (62%) were successfully (MNC >3.5 x 10(8)/kg, CFU-GM >1.0 x 10(4)/kg, CD34+ cells >2.0 x 10(6)/kg and no Ph+ cells in the apheresis product) [n = 16] or partially successfully (as defined above but 1-34% Ph+ cells in the apheresis product) [n = 7] mobilized. There was no mortality during the mobilization procedure. Twenty-one/23 patients subsequently underwent auto-SCT. The time with PMN <0.5 x 10(9)/l was 10 (range 7-49) and with platelets <20 x 10(9)/l was also 10 (2-173) days. There was no transplant related mortality. The estimated 5-year overall survival after auto-SCT was 68% (95% CI 47 - 90%), with a median follow-up time of 5.2 years.We conclude that in a significant proportion of patients with CML in CP 1, intensive chemotherapy combined with G-CSF mobilizes Ph- BSC sufficient for use in auto-SCT.
  • A Bird is Not a Stone : An Anthology of Contemporary Palestinian Poetry translated into the Languages of Scotland
  • 2014
  • Konstnärligt arbete (populärvet., debatt m.m.)abstract
    • A major collection of contemporary Palestinian poetry translated by 24 of Scotland's very best writers including Alasdair Gray, Liz Lochhead, James Robertson, Jackie Kay, William Letford, Aonghas MacNeacail, DM Black, Tom Pow, Ron Butlin and John Glenday. A Bird is not a Stone is a unique cultural exchange, giving both English and Arabic readers a unique insight into the political, social and emotional landscape of today's Palestine. Includes both established and emerging Palestinian poets. Foreword by Scotland's Mackar (Poet Laureate) Liz Lochhead.
  • Abdel-Khalek, Ahmed A., et al. (författare)
  • Chemical Studies on Uranium Extraction from Concentrated Phosphoric Acid by Using PC88A and DBBP Mixture.
  • 2011
  • Ingår i: Journal of Radioanalytical and Nuclear Chemistry. - Springer. - 0236-5731. ; 290, s. 353-359
  • Konstnärligt arbete (refereegranskat)abstract
    • Liquid–liquid extraction of U (VI) from concentrated phosphoric acid by using (2-ethyl hexyl) phosphonic acid, mono (2-ethyl hexyl) ester (PC88A) and di-butyl butyl phosphonate (DBBP) has been investigated. The effect of different factors affecting the extraction process (PC88A concentration, DBBP concentration, shaking time, aqueous/organic phase ratio, phosphoric acid concentration and effect of diluents) have been investigated. The obtained data of temperature on the extraction showed that the enthalpy change is −17.15 kJ mol−1. Uranium was extracted from the strip liquor by using di (2-ethylhexyl) phosphoric acid and tri-octyl phosphine oxide mixture and finally converted to a high purity UO3 product using precipitation with hydrogen peroxide and heat treatment at 365 °C.
  • Acuña, José, 1982-, et al. (författare)
  • Distributed thermal response tests on pipe-in-pipe borehole heat exchangers
  • 2013
  • Ingår i: Applied Energy. - 0306-2619. ; 109:SI, s. 312-320
  • Konstnärligt arbete (refereegranskat)abstract
    • Borehole Thermal Energy Storage systems typically use U-pipe Borehole Heat Exchangers (BHE) having borehole thermal resistances of at least 0.06 K m/W. Obviously, there is room for improvement in the U-pipe design to decrease these values. Additionally, there is a need for methods of getting more detailed knowledge about the performance of BHEs. Performing Distributed Thermal Response Tests (DTRT) on new proposed designs helps to fill this gap, as the ground thermal conductivity and thermal resistances in a BHE can be determined at many instances in the borehole thanks to distributed temperature measurements along the depth. In this paper, results from three heat injection DTRTs carried out on two coaxial pipe-in-pipe BHEs at different flow rates are presented for the first time. The tested pipe-in-pipe geometry consists of a central tube inserted into a larger external flexible pipe, forming an annular space between them. The external pipe is pressed to the borehole wall by applying a slight overpressure at the inside, resulting in good thermal contact and at the same time opening up for a novel method for measuring the borehole wall temperature in situ, by squeezing a fiber optic cable between the external pipe and the borehole wall. A reflection about how to calculate borehole thermal resistance in pipe-in-pipe BHEs is presented. Detailed fluid and borehole wall temperatures along the depth during the whole duration of the DTRTs allowed to calculate local and effective borehole thermal resistances and ground thermal conductivities. Local thermal resistances were found to be almost negligible as compared to U-pipe BHEs, and the effective borehole resistance equal to about 0.03 K m/W. The injected power was found to be almost evenly distributed along the depth.
  • Adamo, Nasrat, et al. (författare)
  • Climate Change: The Uncertain Future of Tigris River Tributaries’ Basins : Climate Change: The Uncertain Future of Tigris River Tributaries’ Basins
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - UK : Scienpress Ltd. - 1792-9040. ; 8:3, s. 75-93
  • Konstnärligt arbete (refereegranskat)abstract
    • Global warming is hitting all parts of the world for the last fifty years due to Global Climate Change and it is expected to continue in the future in an increasing trend unless the present mode of CO2 emission is limited or reversed. This is manifested in the rising temperature over land and the changes induced in the general weather circulation patterns over land and oceans. The Tigris River catchment as most of other parts in the world is suffering from increased temperatures and reduced precipitation contributing to reduced water resources elements all over it and reduction of the river stream flow itself. Studies using the soil and water assessment tool SWAT were performed on the five Tigris River tributaries basins in Iraq in order to assess these impacts. This paper summarizes the results of those studies, the characteristics of each of the five basins, and illustrates the application of SWAT as a tool for future predictions. Moreover, it explains in more details the work done on one of the basins as an example, summarizes the results of the five studies and then analyzes these results and discusses the expected future outcomes. The final conclusion which can be drawn is that severe shortage in all water resources elements will occur over the five basins and the Tigris River stream flow will suffer a considerable decline. This situation demands that policy makers in Iraq should take steps immediately to improve water and soil management practices to try and reduce as much as possible the expected damage that will hit all water using sectors.
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