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A novel blood-based...
A novel blood-based biomarker for detection of autism spectrum disorders
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- Momeni, Naghi (författare)
- Linnéuniversitetet,Institutionen för naturvetenskap, NV,Bengt Persson,School of Natural Sciences, Linnaeus University, Kalmar, Sweden
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- Bergquist, Jonas (författare)
- Uppsala universitet,Analytisk kemi
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- Brudin, Lars (författare)
- Department of Clinical Physiology, Kalmar County Hospital, Kalmar, Sweden,School of Natural Sciences, Linnaeus University, Kalmar, Sweden
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- Behnia, Fatemeh (författare)
- Department of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
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- Sivberg, Bengt (författare)
- Lund University,Lunds universitet,Institutionen för hälsovetenskaper,Medicinska fakulteten,Hälsa i ett tvärvetenskapligt perspektiv,Forskargrupper vid Lunds universitet,Department of Health Sciences,Faculty of Medicine,Integrative Health Research,Lund University Research Groups,Department of Health Sciences, Lund University, Lund, Sweden
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- Joghataei, Mohammad (författare)
- Cellular and Molecular Research Centre, Tehran Medical University, Tehran, Iran
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- Persson, Bengt L., 1951- (författare)
- Linnéuniversitetet,Institutionen för naturvetenskap, NV,Bengt Persson
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(creator_code:org_t)
- 2012-03-13
- 2012
- Engelska.
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Ingår i: Translational Psychiatry. - : Nature Publishing Group. - 2158-3188. ; 2
- Relaterad länk:
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https://doi.org/10.1...
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https://www.nature.c...
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https://portal.resea... (primary) (free)
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http://www.ncbi.nlm.... (free)
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http://dx.doi.org/10... (free)
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Autism Spectrum Disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides which may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass charged (m/z) values of 2,020 ± 1, 1,864 ± 1, and 1,978 ± 1 Da in heparin plasma of children with ASD which were significantly changed as compared to the peptide pattern of the non-ASD control group are reported here. This novel set of biomarkers allows for a reliable blood based diagnostic tool that may be used in diagnosis and potentially, in prognosis of ASD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Nyckelord
- ASD
- autism spectrum disorders
- biomarker
- blood
- Biomedicinsk vetenskap
- Biomedical Sciences
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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