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TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
- Chittani, Martina (author)
- Zaninello, Roberta (author)
- Lanzani, Chiara (author)
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- Frau, Francesca (author)
- Ortu, Maria F (author)
- Salvi, Erika (author)
- Fresu, Giovanni (author)
- Citterio, Lorena (author)
- Braga, Daniele (author)
- Piras, Daniela A (author)
- Carpini, Simona Delli (author)
- Velayutham, Dinesh (author)
- Simonini, Marco (author)
- Argiolas, Giuseppe (author)
- Pozzoli, Simona (author)
- Troffa, Chiara (author)
- Glorioso, Valeria (author)
- Kontula, Kimmo K (author)
- Hiltunen, Timo P (author)
- Donner, Kati M (author)
- Turner, Stephen T (author)
- Boerwinkle, Eric (author)
- Chapman, Arlene B (author)
- Padmanabhan, Sandosh (author)
- Dominiczak, Anna F (author)
- Johnson, Julie A (author)
- Cooper-Dehoff, Rhonda M (author)
- Gong, Yan (author)
- Condorelli, Gianluigi (author)
- Trimarco, Bruno (author)
- Manunta, Paolo (author)
- Cusi, Daniele (author)
- Glorioso, Nicola (author)
- Barlassina, Cristina (author)
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- (creator_code:org_t)
- 2015
- 2015
- English.
- In: Journal of Hypertension. - 1473-5598. ; 33:6, s. 1301-1309
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene variants involved in antihypertensive drug response, thus optimizing therapeutic advantages and minimizing side effects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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- art (subject category)
- ref (subject category)
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- Zaninello, Rober ...
- Lanzani, Chiara
- Frau, Francesca
- Ortu, Maria F
- Salvi, Erika
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- Fresu, Giovanni
- Citterio, Lorena
- Braga, Daniele
- Piras, Daniela A
- Carpini, Simona ...
- Velayutham, Dine ...
- Simonini, Marco
- Argiolas, Giusep ...
- Pozzoli, Simona
- Troffa, Chiara
- Glorioso, Valeri ...
- Kontula, Kimmo K
- Hiltunen, Timo P
- Donner, Kati M
- Turner, Stephen ...
- Boerwinkle, Eric
- Chapman, Arlene ...
- Padmanabhan, San ...
- Dominiczak, Anna ...
- Melander, Olle
- Johnson, Julie A
- Cooper-Dehoff, R ...
- Gong, Yan
- Rivera, Natalia ...
- Condorelli, Gian ...
- Trimarco, Bruno
- Manunta, Paolo
- Cusi, Daniele
- Glorioso, Nicola
- Barlassina, Cris ...
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- Karolinska Institutet
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