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Träfflista för sökning "AMNE:(MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmaceutical Sciences) ;lar1:(hig)"

Sökning: AMNE:(MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmaceutical Sciences) > Högskolan i Gävle

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1.
  • Rolfö, Linda, et al. (författare)
  • Predictors of Preference for the Activity-based Flexible Office
  • 2019
  • Ingår i: Human Systems Engineering and Design. - Cham : Springer. - 9783030020521 - 9783030020538 ; 876, s. 547-553
  • Konferensbidrag (refereegranskat)abstract
    • Activity-based Flexible Offices (A-FOs) are implemented with varying degree of success. Employees relocate from cell or open-plan offices, from different organizational backgrounds, varying design and implementation processes, and have different types of work tasks. This study aims at investigating whether preference for the A-FO correlate with these preconditions. The results from Chi-square tests and Spearman’s non-parametric correlation of post-relocation questionnaires distributed to 11 A-FO sites, showed that a high preference for the A-FO correlated strongest with an A-FO preference prior to relocation, being a former open-plan office occupier and with frequent performance of innovation. Low preference for the A-FO correlated with frequent performance of concentration demanding tasks. Working with tasks with high confidentiality did not predict the preference ratings.
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2.
  • Huttunen, Piritta, et al. (författare)
  • Leaf trichome production and responses to defoliation and drought in Arabidopsis lyrata (Brassicaceae)
  • 2010
  • Ingår i: Annales Botanici Fennici. - Helsinki : Finnish Zoological and Botanical Publishing Board. - 0003-3847 .- 1797-2442. ; 47:3, s. 199-207
  • Tidskriftsartikel (refereegranskat)abstract
    • Leaf trichomes can protect plants against herbivory and drought, but can be costly to produce. Theory suggests that selection for reduced costs of resistance may result in the evolution of inducible defences. We quantified variation in tolerance to drought and defoliation, and tested the hypotheses that (a) tolerance is associated with cost, (b) leaf trichome production increases tolerance to drought, and (c) trichome production is increased in response to defoliation and drought stress in Arabidopsis lyrata (Brassicaceae). Eight maternal half-sib families were exposed to two watering regimes and four defoliation treatments in a factorial design. Tolerance to drought varied among families and was inversely related to leaf size, but was not related to trichome density. Family mean performance in the low-watering treatment tended to correlate negatively with that in the control treatment. Trichome production was not induced by defoliation or drought stress. The results suggest that there is genetic variation in tolerance to drought in the study population, that tolerance to drought is associated with a cost, and that trichome production does not increase tolerance to drought in A. lyrata.
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3.
  • Thunander Sundbom, Lena, 1970-, et al. (författare)
  • Are men under-treated and women over-treated with antidepressants? : Findings from a cross-sectional survey in Sweden
  • 2017
  • Ingår i: BJPsych bulletin. - : Royal College of Psychiatrists. - 2056-4694 .- 2056-4708. ; 41:3, s. 145-150
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims and method: To examine gender differences in self-reported depression and prescribed antidepressants (ADs). The Hospital Anxiety and Depression Scale was used to assess depression, and information on prescribed ADs was obtained from the Swedish Prescribed Drug Register.Results: Depression was reported by 11.7% of the participants (12.3% men and 11.2% women). ADs were prescribed for 7.6% of the participants (5.3% men, 9.8% women). Among men, 1.8% reported depression and used ADs, 10.5% reported depression but did not use ADs, and 3.6% used ADs but did not report depression. The corresponding figures for women were 2.6%, 8.6% and 7.2%.Clinical implications: Men report depression to a greater extent than women but are prescribed ADs to a lesser extent, possibly a sign of under-treatment. Women are prescribed ADs without reporting depression more often than men, possibly a sign of over-treatment. Although the causes remain unclear, diagnostic and treatment guidelines should benefit from considering gender differences in these respects.
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4.
  • Grönbladh, Alfhild, et al. (författare)
  • GH (Growth hormone) improves spatial memory and reverses certain anabolic androgenic steroid-induced effects in intact rats
  • 2013
  • Ingår i: Journal of Endocrinology. - 0022-0795 .- 1479-6805. ; 216:1, s. 31-41
  • Tidskriftsartikel (refereegranskat)abstract
    • Growth hormone (GH) has previously been shown to promote cognitive functions in GH deficient rodents. In this study we report effects of GH on learning and memory in intact rats pretreated with the anabolic androgenic steroid nandrolone. Male Wistar rats received nandrolone decanoate (15 mg/kg) or peanut oil every third day for three weeks and were subsequently treated with recombinant human GH (1.0 IU/kg) or saline for ten consecutive days. During the GH/saline treatment spatial learning and memory were tested in the Morris water maze (MWM). Also, plasma levels of insulin-like growth factor 1 (IGF1) were assessed and the gene expression of the GH receptor, Igf1, and Igf2 in hippocampus and frontal cortex was analyzed. The results demonstrated a significant positive effect of GH on memory functions and increased gene expression of Igf1 in the hippocampus was found in the animals treated with GH. In addition, GH was demonstrated to increase the body weight gain and was able to attenuate the reduced body weight seen in nandrolone treated animals. In general, the rats treated with nandrolone alone did not exhibit any pronounced alteration in memory compared to controls in the MWM, and in many cases GH did not induce any alteration. Regarding target zone crossings, considered to be associated to spatial memory, the difference between GH and steroid treated animals was significant and administration of GH improved this parameter in the latter group. In conclusion, GH improves spatial memory in intact rats and can reverse certain effects induced by AAS (anabolic androgenic steroid).
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