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| 2. |
- Javanshiri, Keivan, et al.
(författare)
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Kardiovaskulär sjukdom och diabetes typ II som riskfaktorer för kognitiv sjukdom
- 2020
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Ingår i: Neurologi i Sverige. - 2000-8538. ; 1:2020, s. 52-55
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Here we presented a review of our two articles presenting the prevalence of cardiovascular disease and diabetes in neurocognitive disorders; Alzheimer's disease, vascular dementia, mixed dementa and Lewy body disease. Cardiovascular disease and diabetes showed a significantly lower prevalence among cases with Alzheimer's disease and Lewy body disease, both neurodegenerative disorders, compared to cases with vascular dementia. These findings strongly argue against the suggestions of Alzheimer's disease and vascular dementia sharing risk factors. All neurocognitive disorders where confirmed through neuropathological examination.
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| 3. |
- Aghanavesi, Somayeh, et al.
(författare)
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Measuring temporal irregularity in spiral drawings of patients with Parkinson’s disease
- 2017
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Ingår i: Abstracts of the 21<sup>st</sup> International Congress of Parkinson's Disease and Movement Disorders. - : John Wiley & Sons. ; , s. s252-s252
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Konferensbidrag (populärvet., debatt m.m.)abstract
- Objective: The aim of this work is to evaluate clinimetric properties of a method for measuring Parkinson’s disease (PD) upper limb temporal irregularities during spiral drawing tasks.Background: Basal ganglia fluctuations of PD patients are associated with motor symptoms and relating them to objective sensor-based measures may facilitate the assessment of temporal irregularities, which could be difficult to be assessed visually. The present study investigated the upper limb temporal irregularity of patients at different stages of PD and medication time points.Methods: Nineteen PD patients and 22 healthy controls performed repeated spiral drawing tasks on a smartphone. Patients performed the tests before a single levodopa dose and at specific time intervals after the dose was given. Three movement disorder specialists rated the videos of patients' performance according to six items of UPDRS-III, dyskinesia (Dys), and Treatment Response Scale (TRS). A temporal irregularity score (TIS) was developed using approximate entropy (ApEn) method. Differences in mean TIS between two groups of patients and healthy subjects, and also across four subject groups: early, intermediate, advanced patients and, healthy subjects were assessed. The relative ability of TIS to detect changes from baseline (no medication) to later time points when patients were on medication was assessed. Correlations between TIS and clinical rating scales were assessed by Pearson correlation coefficients and test-retest reliability of TIS was measured by intra-class correlation coefficients (ICC).Results: The mean TIS was significantly different between healthy subjects and patients (P<0.0001). When assessing the changes in relation to treatment, clinical-based scores (TRS and Dys) had better responsiveness than TIS. However, the TIS was able to capture changes from Off to On, and the wearing off effects. Correlations between TIS and clinical scales were low indicating poor validity. Test-retest reliability correlation coefficient of the mean TIS was good (ICC=0.67).Conclusions: Our study found that TIS was able to differentiate spiral drawings drawn by patients from those drawn by healthy subjects. In addition, TIS could capture changes throughout the levodopa cycle.TIS was weakly correlated to clinical ratings indicating that TIS measures high frequency upper limb temporal irregularities that could be difficult to be detected during clinical observations.
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| 4. |
- Alstermark, Bror, et al.
(författare)
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Anders Lundberg (1920-2009)
- 2010
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Ingår i: Experimental Brain Research. - : Springer. - 0014-4819 .- 1432-1106. ; 200:3-4, s. 193-195
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Anders Lundberg was one of the founding editorial board members for EBR when it began its life in 1976 under the editorship of John Eccles. He was also one of the most prolific contributors to the journal with a total of 49 papers, including a series of 16 on the topic of "integration in descending motor pathways controlling the forelimb in the cat". He continued as an editor of the journal until volume 16 when he persuaded his younger colleague Hans Hultborn to take his place. Hans is one of the authors of the obituary. –John Rothwell
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| 5. |
- Fagius, Jan, et al.
(författare)
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Barnet, hjärnan, musiken och sången
- 2007
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Ingår i: Barn och sång. - Lund : Studentlitteratur. - 9789144019352
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Bokkapitel (populärvet., debatt m.m.)
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| 6. |
- Sandelin, Martin, et al.
(författare)
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Metastasis-associated S100A4 (Mts1) protein is expressed in subpopulations of sensory and autonomic neurons and in Schwann cells of the adult rat.
- 2004
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Ingår i: J Comp Neurol.. ; 473:2, s. 233-43
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- S100A4 (Mts1) is a member of a family of calcium-binding proteins of the EF-hand type, which are widely expressed in the nervous system, where they appear to be involved in the regulation of neuron survival, plasticity, and response to injury or disease. S100A4 has previously been demonstrated in astrocytes of the white matter and rostral migratory stream of the adult rat. After injury, S100A4 is markedly up-regulated in affected central nervous white matter areas as well as in the periventricular area and rostral migratory stream. Here, we show that S100A4 is expressed in a subpopulation of dorsal root, trigeminal, geniculate, and nodose ganglion cells; in a subpopulation of postganglionic sympathetic and parasympathetic neurons; in chromaffin cells of the adrenal medulla; and in satellite and Schwann cells. In dorsal root ganglia, S100A4-positive cells appear to constitute a subpopulation of small ganglion neurons, a few of which coexpressed calcitonin gene-related peptide (CGRP) and Griffonia simplicifolia agglutinin (GSA) isolectin B4 (B4). S100A4 protein appears to be transported from dorsal root ganglia to the spinal cord, where it is deposited in the tract of Lissauer. After peripheral nerve or dorsal root injury, a few S100A4-positive cells coexpress CGRP, GSA, or galanin. Peripheral nerve or dorsal root injury induces a marked up-regulation of S100A4 expression in satellite cells in the ganglion and in Schwann cells at the injury site and in the distal stump. This pattern of distribution partially overlaps that of the previously studied S100B and S100A6 proteins, indicating a possible functional cooperation between these proteins. The presence of S100A4 in sensory neurons, including their processes in the central nervous system, suggests that S100A4 is involved in propagation of sensory impulses in specific fiber types. J. Comp. Neurol. 473:233-243, 2004. © 2004 Wiley-Liss, Inc.
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| 7. |
- Taubner, Helena, 1977-
(författare)
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Afasilinjer på folkhögskola [video]
- 2022
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Annan publikation (film/video) (populärvet., debatt m.m.)abstract
- Helena Taubner är lektor i specialpedagogik vid Jönköping University. Här berättar hon om forskning kring personer med afasi som läser på folkhögskolans afasilinjer, både vad vi vet hittills och vad hon skulle vilja ta reda på.
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| 8. |
- Green, Dido
(författare)
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Translating evidence into practice
- 2014
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Ingår i: Developmental Medicine & Child Neurology. - : Blackwell Publishing Ltd. - 0012-1622 .- 1469-8749. ; 56:12, s. 1132-1133
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 9. |
- Jönsson, Ann-Cathrin, et al.
(författare)
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Neurologiska sjukdomar
- 2016. - 1
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Ingår i: Omvårdnad & medicin. - 9789144076645 ; , s. 155-190
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Bokkapitel (populärvet., debatt m.m.)
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| 10. |
- Ottosson, Johan, et al.
(författare)
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Frysningar vanligast inomhus
- 2012
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Ingår i: Parkinson Journalen. - 1104-2435. ; 3, s. 24-25
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Tidskriftsartikel (populärvet., debatt m.m.)
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