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Sökning: AMNE:(MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Annan klinisk medicin) > Södertörns högskola

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1.
  • Fagerström, Cecilia, Docent, 1973-, et al. (författare)
  • Everyday Health among Older People : A Comparison between Two Countries with Variant Life Conditions
  • 2017
  • Ingår i: Journal of Aging Research. - : Hindawi Limited. - 2090-2204 .- 2090-2212. ; 2017
  • Tidskriftsartikel (refereegranskat)abstract
    • This study described health factors of importance for everyday health, such as pain, tiredness, and sleeping problems, in a cross-national context. Data for persons 60+ years were obtained from the Poverty and Health in Aging study, Bangladesh, and the Swedish National Study on Aging and Care-Blekinge. The strongest associations with everyday health in Sweden were found for pain and tiredness, while in Bangladesh they were financial status, tiredness, and sleeping problems. As similarities were found regarding the associations of tiredness on everyday health, tiredness may be a universal predictor of everyday health in older adults irrespective of country context.
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2.
  • Sundén, Jenny, Professor, 1973- (författare)
  • Networked Intimacies : Pandemic Dis/Connections Between Anxiety, Joy, and Laughter
  • 2021
  • Ingår i: Disentangling. - Oxford : Oxford University Press. - 9780197571873 - 9780197571880 ; , s. 273-294
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • This chapter zooms in on transformations of intimacy and relational spaces in a time of a viral, global crisis. Set against the backdrop of “social distancing” practices, the chapter opens with a discussion of digital intimacy, focusing on the layering of anxiety and anticipation within networked connectivity. Secondly, it moves on to discuss how such anticipatory anxiety may become punctuated by pleasure and joy. Considering the dynamics between physical disconnection and digital intensity within pandemic hookup practices, it explores in particular instances of quarantine humor in queer hookup cultures. This humor stems from impossibly contradictory spaces of self-isolation, desire, and longing, in relation to which the swiftness of the swipe is transformed into a disconnect in the shape of a delay. The chapter ends with an example of Swedish, queer quarantine humor and a discussion of partial disconnections, or selective connectivity in difficult times in the interest of self-care.
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3.
  • Porseryd, Tove, et al. (författare)
  • Testis transcriptome alterations in zebrafish (Danio rerio) with reduced fertility due to developmental exposure to 17α-ethinyl estradiol
  • 2018
  • Ingår i: General and Comparative Endocrinology. - : Academic Press. - 0016-6480 .- 1095-6840. ; 262, s. 44-58
  • Tidskriftsartikel (refereegranskat)abstract
    • 17α-Ethinylestradiol (EE2) is a ubiquitous aquatic contaminant shown to decrease fish fertility at low concentrations, especially in fish exposed during development. The mechanisms of the decreased fertility are not fully understood. In this study, we perform transcriptome analysis by RNA sequencing of testes from zebrafish with previously reported lowered fertility due to exposure to low concentrations of EE2during development. Fish were exposed to 1.2 and 1.6 ng/L (measured concentration; nominal concentrations 3 and 10 ng/L) of EE2 from fertilization to 80 days of age, followed by 82 days of remediation in clean water. RNA sequencing analysis revealed 249 and 16 genes to be differentially expressed after exposure to 1.2 and 1.6 ng/L, respectively; a larger inter-sample variation was noted in the latter. Expression of 11 genes were altered by both exposures and in the same direction. The coding sequences most affected could be categorized to the putative functions cell signalling, proteolysis, protein metabolic transport and lipid metabolic process. Several homeobox transcription factors involved in development and differentiation showed increased expression in response to EE2 and differential expression of genes related to cell death, differentiation and proliferation was observed. In addition, several genes related to steroid synthesis, testis development and function were differentially expressed. A number of genes associated with spermatogenesis in zebrafish and/or mouse were also found to be differentially expressed. Further, differences in non-coding sequences were observed, among them several differentially expressed miRNA that might contribute to testis gene regulation at post-transcriptional level. This study has generated insights of changes in gene expression that accompany fertility alterations in zebrafish males that persist after developmental exposure to environmental relevant concentrations of EE2 that persist followed by clean water to adulthood. Hopefully, this will generate hypotheses to test in search for mechanistic explanations.
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4.
  • Gunnarsson Payne, Jenny, 1976- (författare)
  • Reproduction in Transition : Cross-border egg donation, biodesirability and new reproductive subjectivities on the European fertility market
  • 2015
  • Ingår i: Gender, Place and Culture. - 0966-369X .- 1360-0524. ; 22:1, s. 107-122
  • Tidskriftsartikel (refereegranskat)abstract
    • Today, there should be little doubt that new reproductive technologies have ‘diversified, globalized, and denaturalized’ human reproduction (Inhorn and Birenbaum-Carmeli 2008). Not only have assisted reproductive technologies developed and spread throughout the world at a rapid pace, but this significant development has also given rise to a global market of cross-border reproductive care (CBRC). This article seeks to investigate CBRC between Sweden and the Baltic states, in which Swedish infertility patients travel to private fertility clinics as recipients of egg donation. This article argues that the restructuring of the European space (occurring in and through both the so-called ‘transition’ of the former Eastern Bloc and the expansion of the European Union) constitutes crucial conditions of emergence for the trans-European market of infertility care, which not only results in new modalities of reproductive mobility but also articulates a new set of interrelated European gendered reproductive subjectivities. Particular attention will be paid to the ways in which such ‘new reproductive subjectivities’ – here exemplified by a sample of cross-border donor egg recipients – are articulated in relation to notions of ‘choice’ and what I call ‘biodesirability’, and how such notions cannot be exempt from its specific post-socialist European context.
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6.
  • Finkel, Deborah, et al. (författare)
  • Functional Aging Index Complements Frailty in Prediction of Entry into Care and Mortality.
  • 2019
  • Ingår i: The journals of gerontology. Series A, Biological sciences and medical sciences. - : Oxford University Press. - 1079-5006 .- 1758-535X. ; 74:12, s. 1980-1986
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The aim was to develop a functional aging index (FAI) that taps four body systems: sensory (vision and hearing), pulmonary, strength (grip strength), and movement/balance (gait speed) and to test the predictive value of FAI for entry into care and mortality.METHOD: Growth curve models and cox regression models were applied to data from 1695 individuals from three Swedish longitudinal studies of aging. Participants were aged 45 to 93 at intake and data from up to 8 follow-up waves were available.RESULTS: The rate of change in FAI was twice as fast after age 75 as before, women demonstrated higher mean FAI, but no sex differences in rates of change with chronological age were identified. FAI predicted entry into care and mortality, even when chronological age and a frailty index were included in the models. Hazard ratios indicated FAI was a more important predictor of entry into care for men than women; whereas it was a stronger predictor of mortality for men than women.CONCLUSIONS: Measures of biological aging and functional aging differ in their predictive value for entry into care and mortality for men and women, suggesting that both are necessary for a complete picture of the aging process across genders.
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7.
  • Sternäng, Ola, et al. (författare)
  • Associations Between Functional Biological Age and Cognition Among Older Adults in Rural Bangladesh : Comparisons With Chronological Age
  • 2019
  • Ingår i: Journal of Aging and Health. - : SAGE Publications. - 0898-2643 .- 1552-6887. ; 31:5, s. 814-836
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives: We constructed a functional biological age (fBioAge) indicator by using four functional variables: grip strength, forced expiratory lung volume, visual acuity, and hearing. Our aim was to compare how chronological age (ChronAge) and fBioAge are related to cognitive abilities in older adults. Method: We used data from the Poverty and Health in Aging project, Bangladesh. Participants (N = 400) were 60+ years of age and diagnosed as nondemented. Examined cognitive abilities were four episodic memory measures (including recall and recognition), two verbal fluency indicators, two semantic knowledge, and two processing speed tasks. Results: fBioAge accounted for cognitive variance beyond that explained by ChronAge also after controlling for medical diagnoses and blood markers. Discussion: Compared with ChronAge, fBioAge was a stronger predictor of cognition during a broad part of the old adult span. fBioAge seems, in that respect, to have the potential to become a useful age indicator in future aging studies.
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8.
  • Ehrnberger, Karin, 1977-, et al. (författare)
  • The Androchair : Performing Gynaecology through the Practice of Gender Critical Design
  • 2017
  • Ingår i: The Design Journal. - Abingdon : Routledge. - 1460-6925 .- 1756-3062. ; 20:2, s. 181-198
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper highlights the important role that design plays when it comes to women's overall experiences of ther gynaecological examination. It exemplifies how the examination can become renegotiable through the practice of a critical design. We will reflect this in the design of the contemporary gynaecological examination chair (GEC). We used women's experiences as a starting point for the design of an Androchair (a conceptual male equivalent of the GEC), in order to make the experiences critically visible. Inspired by the view of the gynaecological examination as a performance where the Androchair is represented as a prop and was placed on a stage as a discussion object during a public seminar. The Androchair allowed for both critical and multiple readings of the GEC and through that, the gynaecology examination at large. Moreover, it stimulated a discussion about alternative ideas towards achieving a more positive experience. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
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9.
  • Olsen, Henrik, et al. (författare)
  • To the Editor
  • 2014
  • Ingår i: The Journal of clinical endocrinology and metabolism. - Stockholm : The Endocrine Society. - 1945-7197 .- 0021-972X. ; 99:11, s. 1-2:2, s. 7-15
  • Tidskriftsartikel (refereegranskat)
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10.
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