Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome.

• Eleven patients with disseminated midgut carcinoid tumour disease were subjected to hepatic artery embolisation. In six patients, lymphocytosis with a predominance of NK cells occurred and the cytotoxic activity of isolated lymphocytes increased. A relation between NK cell accumulation and subsequent radiological and biochemical response was observed, and it is suggested that anti-tumour mechanisms other than ischaemia may contribute to the therapeutic response in these patients.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Cytotoxicity

Immunologic

Embolization

Therapeutic

Hepatic Artery

Humans

Intestinal Neoplasms

pathology

therapy

Killer Cells

Natural

cytology

immunology

Liver Neoplasms

immunology

secondary

therapy

Lymphocytes

cytology

immunology

Malignant Carcinoid Syndrome

immunology

pathology

therapy

Phenotype

Publication and Content Type

ref (subject category)

art (subject category)